Modeling the drug withdrawal syndrome in zebrafish (Danio rerio). / Zabegalov, Konstantin N.; Galstyan, David S.; Kolesnikova, Tatyana O. et al.
In: Reviews on Clinical Pharmacology and Drug Therapy, Vol. 20, No. 2, 2022, p. 185-191.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Modeling the drug withdrawal syndrome in zebrafish (Danio rerio)
AU - Zabegalov, Konstantin N.
AU - Galstyan, David S.
AU - Kolesnikova, Tatyana O.
AU - Kositsyn, Yurii M.
AU - Gubaidullina, Mariya A.
AU - Maslov, Gleb O.
AU - Demin, Konstantin A.
AU - Khatsko, Sergey L.
AU - Kalueff, Allan V.
N1 - Публикация на корректировке.
PY - 2022
Y1 - 2022
N2 - The central pathological link in addictive states is the drug withdrawal syndrome. Usually, severe manifestations of the withdrawal syndrome are associated with reduced sensitivity of postsynaptic receptors (desensitization), lower den-sity of receptors and impaired transport of neurotransmitters, and the rebound effect. Zebrafish is an effective tool in the study of classic withdrawal symptoms and special cases of withdrawal of other selected psychoactive drugs.
AB - The central pathological link in addictive states is the drug withdrawal syndrome. Usually, severe manifestations of the withdrawal syndrome are associated with reduced sensitivity of postsynaptic receptors (desensitization), lower den-sity of receptors and impaired transport of neurotransmitters, and the rebound effect. Zebrafish is an effective tool in the study of classic withdrawal symptoms and special cases of withdrawal of other selected psychoactive drugs.
KW - addiction
KW - ethanol
KW - morphine
KW - withdrawal syndrome
KW - zebrafish
UR - https://www.mendeley.com/catalogue/211aa837-37d4-31d7-b049-b6a30354ba32/
U2 - 10.17816/RCF202185-191
DO - 10.17816/RCF202185-191
M3 - Article
VL - 20
SP - 185
EP - 191
JO - Reviews on Clinical Pharmacology and Drug Therapy
JF - Reviews on Clinical Pharmacology and Drug Therapy
SN - 2542-1875
IS - 2
ER -
ID: 55698415