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Mechanical properties and biological behavior of 3D matrices produced by electrospinning from protein-enriched polyurethane. / Chernonosova, Vera S.; Gostev, Alexander A.; Gao, Yun et al.

In: BioMed Research International, Vol. 2018, 1380606, 01.01.2018, p. 1380606.

Research output: Contribution to journal › Article › peer-review

Harvard

Chernonosova, VS, Gostev, AA, Gao, Y, Chesalov, YA, Shutov, AV, Pokushalov, EA, Karpenko, AA & Laktionov, PP 2018, 'Mechanical properties and biological behavior of 3D matrices produced by electrospinning from protein-enriched polyurethane', BioMed Research International, vol. 2018, 1380606, pp. 1380606. https://doi.org/10.1155/2018/1380606

APA

Chernonosova, V. S., Gostev, A. A., Gao, Y., Chesalov, Y. A., Shutov, A. V., Pokushalov, E. A., Karpenko, A. A., & Laktionov, P. P. (2018). Mechanical properties and biological behavior of 3D matrices produced by electrospinning from protein-enriched polyurethane. BioMed Research International, 2018, 1380606. [1380606]. https://doi.org/10.1155/2018/1380606

Vancouver

Chernonosova VS, Gostev AA, Gao Y, Chesalov YA, Shutov AV, Pokushalov EA et al. Mechanical properties and biological behavior of 3D matrices produced by electrospinning from protein-enriched polyurethane. BioMed Research International. 2018 Jan 1;2018:1380606. 1380606. doi: 10.1155/2018/1380606

Author

Chernonosova, Vera S. ; Gostev, Alexander A. ; Gao, Yun et al. / Mechanical properties and biological behavior of 3D matrices produced by electrospinning from protein-enriched polyurethane. In: BioMed Research International. 2018 ; Vol. 2018. pp. 1380606.

BibTeX

@article{462c2633a7eb486abce3a3ecd6052941,
title = "Mechanical properties and biological behavior of 3D matrices produced by electrospinning from protein-enriched polyurethane",
abstract = "Properties of matrices manufactured by electrospinning from solutions of polyurethane Tecoflex EG-80A with gelatin in 1,1,1,3,3,3-hexafluoroisopropanol were studied. The concentration of gelatin added to the electrospinning solution was shown to influence the mechanical properties of matrices: the dependence of matrix tensile strength on protein concentration is described by a bell-shaped curve and an increase in gelatin concentration added to the elasticity of the samples. SEM, FTIR spectroscopy, and mechanical testing demonstrate that incubation of matrices in phosphate buffer changes the structure of the fibers and alters the polyurethane-gelatin interactions, increasing matrix durability. The ability of the matrices to maintain adhesion and proliferation of human endothelial cells was studied. The results suggest that matrices made of 3% polyurethane solution with 15% gelatin (wt/wt) and treated with glutaraldehyde are the optimal variant for cultivation of endothelial cells.",
keywords = "Elasticity, Endothelial Cells, Gelatin, Humans, Polyurethanes/chemistry, Tensile Strength, Tissue Engineering, GELATIN, TECOPHILIC/GELATIN NANOFIBERS, VASCULAR GRAFT, RELEASE, SURFACE-ROUGHNESS, HUMAN ENDOTHELIAL-CELLS, IN-VITRO, TISSUE ENGINEERING APPLICATIONS, DEGRADATION, SCAFFOLDS",
author = "Chernonosova, {Vera S.} and Gostev, {Alexander A.} and Yun Gao and Chesalov, {Yuriy A.} and Shutov, {Alexey V.} and Pokushalov, {Evgeniy A.} and Karpenko, {Andrey A.} and Laktionov, {Pavel P.}",
note = "Publisher Copyright: {\textcopyright} 2018 Vera S. Chernonosova et al.",
year = "2018",
month = jan,
day = "1",
doi = "10.1155/2018/1380606",
language = "English",
volume = "2018",
pages = "1380606",
journal = "BioMed Research International",
issn = "2314-6133",
publisher = "Hindawi Publishing Corporation",

}

RIS

TY - JOUR

T1 - Mechanical properties and biological behavior of 3D matrices produced by electrospinning from protein-enriched polyurethane

AU - Chernonosova, Vera S.

AU - Gostev, Alexander A.

AU - Gao, Yun

AU - Chesalov, Yuriy A.

AU - Shutov, Alexey V.

AU - Pokushalov, Evgeniy A.

AU - Karpenko, Andrey A.

AU - Laktionov, Pavel P.

N1 - Publisher Copyright: © 2018 Vera S. Chernonosova et al.

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Properties of matrices manufactured by electrospinning from solutions of polyurethane Tecoflex EG-80A with gelatin in 1,1,1,3,3,3-hexafluoroisopropanol were studied. The concentration of gelatin added to the electrospinning solution was shown to influence the mechanical properties of matrices: the dependence of matrix tensile strength on protein concentration is described by a bell-shaped curve and an increase in gelatin concentration added to the elasticity of the samples. SEM, FTIR spectroscopy, and mechanical testing demonstrate that incubation of matrices in phosphate buffer changes the structure of the fibers and alters the polyurethane-gelatin interactions, increasing matrix durability. The ability of the matrices to maintain adhesion and proliferation of human endothelial cells was studied. The results suggest that matrices made of 3% polyurethane solution with 15% gelatin (wt/wt) and treated with glutaraldehyde are the optimal variant for cultivation of endothelial cells.

AB - Properties of matrices manufactured by electrospinning from solutions of polyurethane Tecoflex EG-80A with gelatin in 1,1,1,3,3,3-hexafluoroisopropanol were studied. The concentration of gelatin added to the electrospinning solution was shown to influence the mechanical properties of matrices: the dependence of matrix tensile strength on protein concentration is described by a bell-shaped curve and an increase in gelatin concentration added to the elasticity of the samples. SEM, FTIR spectroscopy, and mechanical testing demonstrate that incubation of matrices in phosphate buffer changes the structure of the fibers and alters the polyurethane-gelatin interactions, increasing matrix durability. The ability of the matrices to maintain adhesion and proliferation of human endothelial cells was studied. The results suggest that matrices made of 3% polyurethane solution with 15% gelatin (wt/wt) and treated with glutaraldehyde are the optimal variant for cultivation of endothelial cells.

KW - Elasticity

KW - Endothelial Cells

KW - Gelatin

KW - Humans

KW - Polyurethanes/chemistry

KW - Tensile Strength

KW - Tissue Engineering

KW - GELATIN

KW - TECOPHILIC/GELATIN NANOFIBERS

KW - VASCULAR GRAFT

KW - RELEASE

KW - SURFACE-ROUGHNESS

KW - HUMAN ENDOTHELIAL-CELLS

KW - IN-VITRO

KW - TISSUE ENGINEERING APPLICATIONS

KW - DEGRADATION

KW - SCAFFOLDS

UR - http://www.scopus.com/inward/record.url?scp=85049830964&partnerID=8YFLogxK

U2 - 10.1155/2018/1380606

DO - 10.1155/2018/1380606

M3 - Article

C2 - 30046587

AN - SCOPUS:85049830964

VL - 2018

SP - 1380606

JO - BioMed Research International

JF - BioMed Research International

SN - 2314-6133

M1 - 1380606

ER -

ID: 14883008