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H3K9 and H4K20 methyltransferases are directly involved in the heterochromatinization of the paternal chromosomes in male Planococcus citri embryos. / Osipov, Yakov A; Posukh, Olga V; Kalashnikova, Darya A et al.

In: Chromosoma, Vol. 132, No. 4, 11.2023, p. 317-328.

Research output: Contribution to journal › Article › peer-review

Harvard

Osipov, YA, Posukh, OV, Kalashnikova, DA, Antoshina, PA, Laktionov, PP, Skrypnik, PA, Belyakin, SN & Singh, PB 2023, 'H3K9 and H4K20 methyltransferases are directly involved in the heterochromatinization of the paternal chromosomes in male Planococcus citri embryos', Chromosoma, vol. 132, no. 4, pp. 317-328. https://doi.org/10.1007/s00412-023-00809-3

APA

Osipov, Y. A., Posukh, O. V., Kalashnikova, D. A., Antoshina, P. A., Laktionov, P. P., Skrypnik, P. A., Belyakin, S. N., & Singh, P. B. (2023). H3K9 and H4K20 methyltransferases are directly involved in the heterochromatinization of the paternal chromosomes in male Planococcus citri embryos. Chromosoma, 132(4), 317-328. https://doi.org/10.1007/s00412-023-00809-3

Vancouver

Osipov YA, Posukh OV, Kalashnikova DA, Antoshina PA, Laktionov PP, Skrypnik PA et al. H3K9 and H4K20 methyltransferases are directly involved in the heterochromatinization of the paternal chromosomes in male Planococcus citri embryos. Chromosoma. 2023 Nov;132(4):317-328. doi: 10.1007/s00412-023-00809-3

Author

Osipov, Yakov A ; Posukh, Olga V ; Kalashnikova, Darya A et al. / H3K9 and H4K20 methyltransferases are directly involved in the heterochromatinization of the paternal chromosomes in male Planococcus citri embryos. In: Chromosoma. 2023 ; Vol. 132, No. 4. pp. 317-328.

BibTeX

@article{225b99aa9bdd4005b29e26823b34524f,
title = "H3K9 and H4K20 methyltransferases are directly involved in the heterochromatinization of the paternal chromosomes in male Planococcus citri embryos",
abstract = "Using a new method for bulk preparation of early stage embryos, we have investigated the role played by putative Planococcus citri H3K9 and H4K20 histone methyl transferases (HMTases) in regulating heterochromatinization of the imprinted paternal chromosomal set in male embryos. We found that H3K9 and H420 HMTases are required for heterochromatinization of the paternal chromosomes. We present evidence that both HMTases maintain the paternal {"}imprint{"} during the cleavage divisions when both parental chromosome sets are euchromatic. A testable model that accommodates our findings is proposed.",
keywords = "Epigenetics, Genomic imprinting, H3K9me3:HP1:H4K20me3 pathway, Heterochromatin, Heterochromatin/genetics, Humans, Male, Methyltransferases/genetics, Histones/genetics",
author = "Osipov, {Yakov A} and Posukh, {Olga V} and Kalashnikova, {Darya A} and Antoshina, {Polina A} and Laktionov, {Petr P} and Skrypnik, {Polina A} and Belyakin, {Stepan N} and Singh, {Prim B}",
note = "This work was funded by a grant from the Ministry of Education and Science of Russian Federation #14.Y26.31.0024 and Nazarbayev University Faculty Development Grant 021220FD2451 awarded to PBS. It was partially supported by the Russian Fundamental Scientific Research Project: FWGZ-2021–0017. {\textcopyright} 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.",
year = "2023",
month = nov,
doi = "10.1007/s00412-023-00809-3",
language = "English",
volume = "132",
pages = "317--328",
journal = "Chromosoma",
issn = "0009-5915",
publisher = "Springer Science and Business Media Deutschland GmbH",
number = "4",

}

RIS

TY - JOUR

T1 - H3K9 and H4K20 methyltransferases are directly involved in the heterochromatinization of the paternal chromosomes in male Planococcus citri embryos

AU - Osipov, Yakov A

AU - Posukh, Olga V

AU - Kalashnikova, Darya A

AU - Antoshina, Polina A

AU - Laktionov, Petr P

AU - Skrypnik, Polina A

AU - Belyakin, Stepan N

AU - Singh, Prim B

N1 - This work was funded by a grant from the Ministry of Education and Science of Russian Federation #14.Y26.31.0024 and Nazarbayev University Faculty Development Grant 021220FD2451 awarded to PBS. It was partially supported by the Russian Fundamental Scientific Research Project: FWGZ-2021–0017. © 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

PY - 2023/11

Y1 - 2023/11

N2 - Using a new method for bulk preparation of early stage embryos, we have investigated the role played by putative Planococcus citri H3K9 and H4K20 histone methyl transferases (HMTases) in regulating heterochromatinization of the imprinted paternal chromosomal set in male embryos. We found that H3K9 and H420 HMTases are required for heterochromatinization of the paternal chromosomes. We present evidence that both HMTases maintain the paternal "imprint" during the cleavage divisions when both parental chromosome sets are euchromatic. A testable model that accommodates our findings is proposed.

AB - Using a new method for bulk preparation of early stage embryos, we have investigated the role played by putative Planococcus citri H3K9 and H4K20 histone methyl transferases (HMTases) in regulating heterochromatinization of the imprinted paternal chromosomal set in male embryos. We found that H3K9 and H420 HMTases are required for heterochromatinization of the paternal chromosomes. We present evidence that both HMTases maintain the paternal "imprint" during the cleavage divisions when both parental chromosome sets are euchromatic. A testable model that accommodates our findings is proposed.

KW - Epigenetics

KW - Genomic imprinting

KW - H3K9me3:HP1:H4K20me3 pathway

KW - Heterochromatin

KW - Heterochromatin/genetics

KW - Humans

KW - Male

KW - Methyltransferases/genetics

KW - Histones/genetics

UR - https://www.scopus.com/record/display.uri?eid=2-s2.0-85171192535&origin=inward&txGid=6dd8143f6fc560a134cdfb1eab0196e1

UR - https://www.mendeley.com/catalogue/f3737645-2877-367a-a4a9-6c294e501d2b/

U2 - 10.1007/s00412-023-00809-3

DO - 10.1007/s00412-023-00809-3

M3 - Article

C2 - 37700063

VL - 132

SP - 317

EP - 328

JO - Chromosoma

JF - Chromosoma

SN - 0009-5915

IS - 4

ER -

ID: 55300235