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Germline-restricted chromosome (GRC) is widespread among songbirds. / Torgasheva, Anna A.; Malinovskaya, Lyubov P.; Zadesenets, Kira S. et al.

In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, No. 24, 11.06.2019, p. 11845-11850.

Research output: Contribution to journal › Article › peer-review

Harvard

Torgasheva, AA, Malinovskaya, LP, Zadesenets, KS, Karamysheva, TV, Kizilova, EA, Akberdina, EA, Pristyazhnyuk, IE, Shnaider, EP, Volodkina, VA, Saifitdinova, AF, Galkina, SA, Larkin, DM, Rubtsov, NB & Borodin, PM 2019, 'Germline-restricted chromosome (GRC) is widespread among songbirds', Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 24, pp. 11845-11850. https://doi.org/10.1073/pnas.1817373116

APA

Torgasheva, A. A., Malinovskaya, L. P., Zadesenets, K. S., Karamysheva, T. V., Kizilova, E. A., Akberdina, E. A., Pristyazhnyuk, I. E., Shnaider, E. P., Volodkina, V. A., Saifitdinova, A. F., Galkina, S. A., Larkin, D. M., Rubtsov, N. B., & Borodin, P. M. (2019). Germline-restricted chromosome (GRC) is widespread among songbirds. Proceedings of the National Academy of Sciences of the United States of America, 116(24), 11845-11850. https://doi.org/10.1073/pnas.1817373116

Vancouver

Torgasheva AA, Malinovskaya LP, Zadesenets KS, Karamysheva TV, Kizilova EA, Akberdina EA et al. Germline-restricted chromosome (GRC) is widespread among songbirds. Proceedings of the National Academy of Sciences of the United States of America. 2019 Jun 11;116(24):11845-11850. doi: 10.1073/pnas.1817373116

Author

Torgasheva, Anna A. ; Malinovskaya, Lyubov P. ; Zadesenets, Kira S. et al. / Germline-restricted chromosome (GRC) is widespread among songbirds. In: Proceedings of the National Academy of Sciences of the United States of America. 2019 ; Vol. 116, No. 24. pp. 11845-11850.

BibTeX

@article{88f425f133ca4405b1c62947d17e39b7,
title = "Germline-restricted chromosome (GRC) is widespread among songbirds",
abstract = "An unusual supernumerary chromosome has been reported for two related avian species, the zebra and Bengalese finches. This large, germline-restricted chromosome (GRC) is eliminated from somatic cells and spermatids and transmitted via oocytes only. Its origin, distribution among avian lineages, and function were mostly unknown so far. Using immunolocalization of key meiotic proteins, we found that GRCs of varying size and genetic content are present in all 16 songbird species investigated and absent from germline genomes of all eight examined bird species from other avian orders. Results of fluorescent in situ hybridization of microdissected GRC probes and their sequencing indicate that GRCs show little homology between songbird species and contain a variety of repetitive elements and unique sequences with paralogs in the somatic genome. Our data suggest that the GRC evolved in the common ancestor of all songbirds and underwent significant changes in the extant descendant lineages.",
keywords = "Avian genome, chromosome evolution, meiosis, Passeriformes, programmed DNA elimination",
author = "Torgasheva, {Anna A.} and Malinovskaya, {Lyubov P.} and Zadesenets, {Kira S.} and Karamysheva, {Tatyana V.} and Kizilova, {Elena A.} and Akberdina, {Ekaterina A.} and Pristyazhnyuk, {Inna E.} and Shnaider, {Elena P.} and Volodkina, {Valeria A.} and Saifitdinova, {Alsu F.} and Galkina, {Svetlana A.} and Larkin, {Denis M.} and Rubtsov, {Nikolai B.} and Borodin, {Pavel M.}",
year = "2019",
month = jun,
day = "11",
doi = "10.1073/pnas.1817373116",
language = "English",
volume = "116",
pages = "11845--11850",
journal = "Proceedings of the National Academy of Sciences of the United States of America",
issn = "0027-8424",
publisher = "National Academy of Sciences",
number = "24",

}

RIS

TY - JOUR

T1 - Germline-restricted chromosome (GRC) is widespread among songbirds

AU - Torgasheva, Anna A.

AU - Malinovskaya, Lyubov P.

AU - Zadesenets, Kira S.

AU - Karamysheva, Tatyana V.

AU - Kizilova, Elena A.

AU - Akberdina, Ekaterina A.

AU - Pristyazhnyuk, Inna E.

AU - Shnaider, Elena P.

AU - Volodkina, Valeria A.

AU - Saifitdinova, Alsu F.

AU - Galkina, Svetlana A.

AU - Larkin, Denis M.

AU - Rubtsov, Nikolai B.

AU - Borodin, Pavel M.

PY - 2019/6/11

Y1 - 2019/6/11

N2 - An unusual supernumerary chromosome has been reported for two related avian species, the zebra and Bengalese finches. This large, germline-restricted chromosome (GRC) is eliminated from somatic cells and spermatids and transmitted via oocytes only. Its origin, distribution among avian lineages, and function were mostly unknown so far. Using immunolocalization of key meiotic proteins, we found that GRCs of varying size and genetic content are present in all 16 songbird species investigated and absent from germline genomes of all eight examined bird species from other avian orders. Results of fluorescent in situ hybridization of microdissected GRC probes and their sequencing indicate that GRCs show little homology between songbird species and contain a variety of repetitive elements and unique sequences with paralogs in the somatic genome. Our data suggest that the GRC evolved in the common ancestor of all songbirds and underwent significant changes in the extant descendant lineages.

AB - An unusual supernumerary chromosome has been reported for two related avian species, the zebra and Bengalese finches. This large, germline-restricted chromosome (GRC) is eliminated from somatic cells and spermatids and transmitted via oocytes only. Its origin, distribution among avian lineages, and function were mostly unknown so far. Using immunolocalization of key meiotic proteins, we found that GRCs of varying size and genetic content are present in all 16 songbird species investigated and absent from germline genomes of all eight examined bird species from other avian orders. Results of fluorescent in situ hybridization of microdissected GRC probes and their sequencing indicate that GRCs show little homology between songbird species and contain a variety of repetitive elements and unique sequences with paralogs in the somatic genome. Our data suggest that the GRC evolved in the common ancestor of all songbirds and underwent significant changes in the extant descendant lineages.

KW - Avian genome

KW - chromosome evolution

KW - meiosis

KW - Passeriformes

KW - programmed DNA elimination

UR - http://www.scopus.com/inward/record.url?scp=85067075265&partnerID=8YFLogxK

U2 - 10.1073/pnas.1817373116

DO - 10.1073/pnas.1817373116

M3 - Article

C2 - 31036668

AN - SCOPUS:85067075265

VL - 116

SP - 11845

EP - 11850

JO - Proceedings of the National Academy of Sciences of the United States of America

JF - Proceedings of the National Academy of Sciences of the United States of America

SN - 0027-8424

IS - 24

ER -

ID: 20558498