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Generation of two iPSC lines (IMGTi001-A and IMGTi001-B) from human skin fibroblasts with ring chromosome 22. / Nikitina, T. V.; Menzorov, A. G.; Kashevarova, A. A. et al.

In: Stem Cell Research, Vol. 31, 01.08.2018, p. 244-248.

Research output: Contribution to journal › Article › peer-review

Harvard

Nikitina, TV, Menzorov, AG, Kashevarova, AA, Gridina, MM, Khabarova, AA, Yakovleva, YS, Lopatkina, ME, Kizilova, EA, Vasilyev, SA, Serov, OL & Lebedev, IN 2018, 'Generation of two iPSC lines (IMGTi001-A and IMGTi001-B) from human skin fibroblasts with ring chromosome 22', Stem Cell Research, vol. 31, pp. 244-248. https://doi.org/10.1016/j.scr.2018.08.012

APA

Nikitina, T. V., Menzorov, A. G., Kashevarova, A. A., Gridina, M. M., Khabarova, A. A., Yakovleva, Y. S., Lopatkina, M. E., Kizilova, E. A., Vasilyev, S. A., Serov, O. L., & Lebedev, I. N. (2018). Generation of two iPSC lines (IMGTi001-A and IMGTi001-B) from human skin fibroblasts with ring chromosome 22. Stem Cell Research, 31, 244-248. https://doi.org/10.1016/j.scr.2018.08.012

Vancouver

Nikitina TV, Menzorov AG, Kashevarova AA, Gridina MM, Khabarova AA, Yakovleva YS et al. Generation of two iPSC lines (IMGTi001-A and IMGTi001-B) from human skin fibroblasts with ring chromosome 22. Stem Cell Research. 2018 Aug 1;31:244-248. doi: 10.1016/j.scr.2018.08.012

Author

Nikitina, T. V. ; Menzorov, A. G. ; Kashevarova, A. A. et al. / Generation of two iPSC lines (IMGTi001-A and IMGTi001-B) from human skin fibroblasts with ring chromosome 22. In: Stem Cell Research. 2018 ; Vol. 31. pp. 244-248.

BibTeX

@article{31d70373cbc34f7d9f3615322f4f146c,
title = "Generation of two iPSC lines (IMGTi001-A and IMGTi001-B) from human skin fibroblasts with ring chromosome 22",
abstract = "Skin fibroblasts from a patient with intellectual disability and ring chromosome 22 were reprogrammed into induced pluripotent stem cells (iPSCs) to establish a clonal stem cell lines, IMGTi001-A (iTAF5-29) and IMGTi001-B (iTAF5-32). Because of ring chromosome mitotic instability these cell lines show mosaic karyotypes with 46,XX,r(22) in >83% cells, 45,XX,-22 as minor class and sporadically cells with other karyotypes. Differentiation in derivatives of all three germ layers was shown in teratoma assay for IMGTi001-A, and in embryoid bodies for both cell lines. To our knowledge, human iPSC lines with ring chromosome are described for the first time.",
keywords = "Child, Preschool, Female, Fibroblasts/metabolism, Humans, Induced Pluripotent Stem Cells/metabolism, Ring Chromosomes, Skin/growth & development",
author = "Nikitina, {T. V.} and Menzorov, {A. G.} and Kashevarova, {A. A.} and Gridina, {M. M.} and Khabarova, {A. A.} and Yakovleva, {Yu S.} and Lopatkina, {M. E.} and Kizilova, {E. A.} and Vasilyev, {S. A.} and Serov, {O. L.} and Lebedev, {I. N.}",
note = "Publisher Copyright: {\textcopyright} 2018 The Authors",
year = "2018",
month = aug,
day = "1",
doi = "10.1016/j.scr.2018.08.012",
language = "English",
volume = "31",
pages = "244--248",
journal = "Stem Cell Research",
issn = "1873-5061",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Generation of two iPSC lines (IMGTi001-A and IMGTi001-B) from human skin fibroblasts with ring chromosome 22

AU - Nikitina, T. V.

AU - Menzorov, A. G.

AU - Kashevarova, A. A.

AU - Gridina, M. M.

AU - Khabarova, A. A.

AU - Yakovleva, Yu S.

AU - Lopatkina, M. E.

AU - Kizilova, E. A.

AU - Vasilyev, S. A.

AU - Serov, O. L.

AU - Lebedev, I. N.

N1 - Publisher Copyright: © 2018 The Authors

PY - 2018/8/1

Y1 - 2018/8/1

N2 - Skin fibroblasts from a patient with intellectual disability and ring chromosome 22 were reprogrammed into induced pluripotent stem cells (iPSCs) to establish a clonal stem cell lines, IMGTi001-A (iTAF5-29) and IMGTi001-B (iTAF5-32). Because of ring chromosome mitotic instability these cell lines show mosaic karyotypes with 46,XX,r(22) in >83% cells, 45,XX,-22 as minor class and sporadically cells with other karyotypes. Differentiation in derivatives of all three germ layers was shown in teratoma assay for IMGTi001-A, and in embryoid bodies for both cell lines. To our knowledge, human iPSC lines with ring chromosome are described for the first time.

AB - Skin fibroblasts from a patient with intellectual disability and ring chromosome 22 were reprogrammed into induced pluripotent stem cells (iPSCs) to establish a clonal stem cell lines, IMGTi001-A (iTAF5-29) and IMGTi001-B (iTAF5-32). Because of ring chromosome mitotic instability these cell lines show mosaic karyotypes with 46,XX,r(22) in >83% cells, 45,XX,-22 as minor class and sporadically cells with other karyotypes. Differentiation in derivatives of all three germ layers was shown in teratoma assay for IMGTi001-A, and in embryoid bodies for both cell lines. To our knowledge, human iPSC lines with ring chromosome are described for the first time.

KW - Child, Preschool

KW - Female

KW - Fibroblasts/metabolism

KW - Humans

KW - Induced Pluripotent Stem Cells/metabolism

KW - Ring Chromosomes

KW - Skin/growth & development

UR - http://www.scopus.com/inward/record.url?scp=85051820165&partnerID=8YFLogxK

U2 - 10.1016/j.scr.2018.08.012

DO - 10.1016/j.scr.2018.08.012

M3 - Article

C2 - 30144655

AN - SCOPUS:85051820165

VL - 31

SP - 244

EP - 248

JO - Stem Cell Research

JF - Stem Cell Research

SN - 1873-5061

ER -

ID: 16112257