Research output: Contribution to journal › Article › peer-review
Generation of two iPSC lines, (ICGi015-A and ICGi015-B), by reprogramming peripheral blood mononuclear cells from a patient with Parkinson's disease. / Sharipova, D. V.; Kovalenko, V. R.; Bairamova, E. M. et al.
In: Stem Cell Research, Vol. 41, 101652, 01.12.2019.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Generation of two iPSC lines, (ICGi015-A and ICGi015-B), by reprogramming peripheral blood mononuclear cells from a patient with Parkinson's disease
AU - Sharipova, D. V.
AU - Kovalenko, V. R.
AU - Bairamova, E. M.
AU - Vartanova, V. A.
AU - Grigor'eva, E. V.
AU - Vyatkin, Y. V.
AU - Khabarova, E. A.
AU - Rzaev, D. A.
AU - Zakian, S. M.
AU - Medvedev, S. P.
N1 - Publisher Copyright: © 2019 The Author(s) Copyright: Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2019/12/1
Y1 - 2019/12/1
N2 - Studying Parkinson's disease (PD), one of the most common neurodegenerative disorders worldwide, requires different model systems, including patient-specific induced pluripotent stem cell lines. With the help of non-integrating episomal vectors the iPSC lines ICGi015-A and ICGi015-B were generated from blood mononuclear cells of PD patient, carrying three SNPs, associated with PD development. The obtained iPSC lines express pluripotency markers and demonstrate the ability to in vitro differentiate into the three germ layers. These cell lines may be useful for studying molecular mechanisms of PD and for drug screening.
AB - Studying Parkinson's disease (PD), one of the most common neurodegenerative disorders worldwide, requires different model systems, including patient-specific induced pluripotent stem cell lines. With the help of non-integrating episomal vectors the iPSC lines ICGi015-A and ICGi015-B were generated from blood mononuclear cells of PD patient, carrying three SNPs, associated with PD development. The obtained iPSC lines express pluripotency markers and demonstrate the ability to in vitro differentiate into the three germ layers. These cell lines may be useful for studying molecular mechanisms of PD and for drug screening.
UR - http://www.scopus.com/inward/record.url?scp=85074781227&partnerID=8YFLogxK
U2 - 10.1016/j.scr.2019.101652
DO - 10.1016/j.scr.2019.101652
M3 - Article
C2 - 31733442
AN - SCOPUS:85074781227
VL - 41
JO - Stem Cell Research
JF - Stem Cell Research
SN - 1873-5061
M1 - 101652
ER -
ID: 22322979