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Frequency of 3’ VNTR polymorphism in the dopamine transporter gene SLC6A3 in humans predisposed to antisocial behavior. / Cherepkova, E. V.; Aftanas, L. I.; Maksimov, V. N. et al.

In: Bulletin of Experimental Biology and Medicine, Vol. 162, No. 1, 01.11.2016, p. 82-85.

Research output: Contribution to journal › Article › peer-review

Harvard

Cherepkova, EV, Aftanas, LI, Maksimov, VN & Menshanov, PN 2016, 'Frequency of 3’ VNTR polymorphism in the dopamine transporter gene SLC6A3 in humans predisposed to antisocial behavior', Bulletin of Experimental Biology and Medicine, vol. 162, no. 1, pp. 82-85. https://doi.org/10.1007/s10517-016-3551-7

APA

Cherepkova, E. V., Aftanas, L. I., Maksimov, V. N., & Menshanov, P. N. (2016). Frequency of 3’ VNTR polymorphism in the dopamine transporter gene SLC6A3 in humans predisposed to antisocial behavior. Bulletin of Experimental Biology and Medicine, 162(1), 82-85. https://doi.org/10.1007/s10517-016-3551-7

Vancouver

Cherepkova EV, Aftanas LI, Maksimov VN, Menshanov PN. Frequency of 3’ VNTR polymorphism in the dopamine transporter gene SLC6A3 in humans predisposed to antisocial behavior. Bulletin of Experimental Biology and Medicine. 2016 Nov 1;162(1):82-85. doi: 10.1007/s10517-016-3551-7

Author

Cherepkova, E. V. ; Aftanas, L. I. ; Maksimov, V. N. et al. / Frequency of 3’ VNTR polymorphism in the dopamine transporter gene SLC6A3 in humans predisposed to antisocial behavior. In: Bulletin of Experimental Biology and Medicine. 2016 ; Vol. 162, No. 1. pp. 82-85.

BibTeX

@article{c7c6ba13696c458e83e2c4da79f7a599,
title = "Frequency of 3{\textquoteright} VNTR polymorphism in the dopamine transporter gene SLC6A3 in humans predisposed to antisocial behavior",
abstract = "Predisposition to antisocial behavior can be related to the presence of certain polymorphic variants of genes encoding dopaminergic system proteins. We studied the frequencies of allele variants and genotypes of variable number tandem repeat polymorphism in 3' untranslated region (3' VTNR) of the dopaminergic transporter SLC6A3 gene in Caucasian men committed socially dangerous violent and non-violent crimes. Alleles with 9 and 10 repeats were most frequent in both the control group and group of men predisposed to antisocial behavior. At the same time, the 10/10 genotype was more frequently observed in the group of men prone to antisocial non-violent behavior. Hence, the presence of certain variants of 3' VTNR polymorphism of SLC6A3 gene in men is associated with predisposition to certain forms of antisocial behavior.",
keywords = "3{\textquoteleft}VNTR polymorphism, Antisocial behavior, Case-control study, Dopamine transporter, SLC6A3",
author = "Cherepkova, {E. V.} and Aftanas, {L. I.} and Maksimov, {V. N.} and Menshanov, {P. N.}",
year = "2016",
month = nov,
day = "1",
doi = "10.1007/s10517-016-3551-7",
language = "English",
volume = "162",
pages = "82--85",
journal = "Bulletin of Experimental Biology and Medicine",
issn = "0007-4888",
publisher = "Springer New York",
number = "1",

}

RIS

TY - JOUR

T1 - Frequency of 3’ VNTR polymorphism in the dopamine transporter gene SLC6A3 in humans predisposed to antisocial behavior

AU - Cherepkova, E. V.

AU - Aftanas, L. I.

AU - Maksimov, V. N.

AU - Menshanov, P. N.

PY - 2016/11/1

Y1 - 2016/11/1

N2 - Predisposition to antisocial behavior can be related to the presence of certain polymorphic variants of genes encoding dopaminergic system proteins. We studied the frequencies of allele variants and genotypes of variable number tandem repeat polymorphism in 3' untranslated region (3' VTNR) of the dopaminergic transporter SLC6A3 gene in Caucasian men committed socially dangerous violent and non-violent crimes. Alleles with 9 and 10 repeats were most frequent in both the control group and group of men predisposed to antisocial behavior. At the same time, the 10/10 genotype was more frequently observed in the group of men prone to antisocial non-violent behavior. Hence, the presence of certain variants of 3' VTNR polymorphism of SLC6A3 gene in men is associated with predisposition to certain forms of antisocial behavior.

AB - Predisposition to antisocial behavior can be related to the presence of certain polymorphic variants of genes encoding dopaminergic system proteins. We studied the frequencies of allele variants and genotypes of variable number tandem repeat polymorphism in 3' untranslated region (3' VTNR) of the dopaminergic transporter SLC6A3 gene in Caucasian men committed socially dangerous violent and non-violent crimes. Alleles with 9 and 10 repeats were most frequent in both the control group and group of men predisposed to antisocial behavior. At the same time, the 10/10 genotype was more frequently observed in the group of men prone to antisocial non-violent behavior. Hence, the presence of certain variants of 3' VTNR polymorphism of SLC6A3 gene in men is associated with predisposition to certain forms of antisocial behavior.

KW - 3‘VNTR polymorphism

KW - Antisocial behavior

KW - Case-control study

KW - Dopamine transporter

KW - SLC6A3

UR - http://www.scopus.com/inward/record.url?scp=84996848806&partnerID=8YFLogxK

U2 - 10.1007/s10517-016-3551-7

DO - 10.1007/s10517-016-3551-7

M3 - Article

C2 - 27882466

AN - SCOPUS:84996848806

VL - 162

SP - 82

EP - 85

JO - Bulletin of Experimental Biology and Medicine

JF - Bulletin of Experimental Biology and Medicine

SN - 0007-4888

IS - 1

ER -

ID: 8715734