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Fast changes in default and control network activity underlying intraindividual response time variability in childhood: Does age and sex matter? / Privodnova, Evgeniya Yu; Slobodskaya, Helena R; Savostyanov, Alexander N et al.

In: Developmental Psychobiology, Vol. 65, No. 4, e22382, 05.2023.

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@article{9d16ba45e2fd4b0dbe2ce45b4d32aea4,
title = "Fast changes in default and control network activity underlying intraindividual response time variability in childhood: Does age and sex matter?",
abstract = "Intraindividual response time variability (RTV) is considered as a general marker of neurological health. In adults, the central executive and salience networks (task-positive networks, TPN) and the default mode network (DMN) are critical for RTV. Given that RTV decreases with growing up, and that boys are likely somewhat behind girls with respect to the network development, we aimed to clarify age and sex effects. Electroencephalogram was recorded during Stroop-like test performance in 124 typically developing children aged 5-12 years. Network fluctuations were calculated as changes of current source density (CSD) in regions of interest (ROIs) from pretest to 1-s test interval. In boys, TPN activation (CSD increase in ROIs included in the TPN) was associated with lower RTV, suggesting a greater engagement of attentional control. In children younger than 9.5 years, higher response stability was associated with the predominance of TPN activation over DMN activation (CSD increase in ROIs included in the TPN > that in the DMN); this predominance increased with age, suggesting that variability among younger children may be due to network immaturity. These findings suggest that the TPN and DMN may play different roles within the network mechanisms of RTV in boys and girls and at different developmental stages.",
keywords = "Adult, Male, Female, Child, Humans, Reaction Time, Attention/physiology, Magnetic Resonance Imaging/methods, Brain, Nerve Net, Brain Mapping, default network, intraindividual response time variability, children, control networks, sex differences",
author = "Privodnova, {Evgeniya Yu} and Slobodskaya, {Helena R} and Savostyanov, {Alexander N} and Bocharov, {Andrey V} and Saprigyn, {Alexander E} and Knyazev, {Gennady G}",
note = "Funding information: Budgetary funding of SRINM for basic research theme, Grant/Award Number: 122042700001-9; Budget project of ICG SB RAS, Grant/Award Number: FWNR-2022-0020; Russian Science Foundation, Grant/Award Number: 16-18-00003; computational resources of the Central Control Committee {"}Bioinformatics{"}. {\textcopyright} 2023 Wiley Periodicals LLC.",
year = "2023",
month = may,
doi = "10.1002/dev.22382",
language = "English",
volume = "65",
journal = "Developmental Psychobiology",
issn = "0012-1630",
publisher = "John Wiley and Sons Inc.",
number = "4",

}

RIS

TY - JOUR

T1 - Fast changes in default and control network activity underlying intraindividual response time variability in childhood: Does age and sex matter?

AU - Privodnova, Evgeniya Yu

AU - Slobodskaya, Helena R

AU - Savostyanov, Alexander N

AU - Bocharov, Andrey V

AU - Saprigyn, Alexander E

AU - Knyazev, Gennady G

N1 - Funding information: Budgetary funding of SRINM for basic research theme, Grant/Award Number: 122042700001-9; Budget project of ICG SB RAS, Grant/Award Number: FWNR-2022-0020; Russian Science Foundation, Grant/Award Number: 16-18-00003; computational resources of the Central Control Committee "Bioinformatics". © 2023 Wiley Periodicals LLC.

PY - 2023/5

Y1 - 2023/5

N2 - Intraindividual response time variability (RTV) is considered as a general marker of neurological health. In adults, the central executive and salience networks (task-positive networks, TPN) and the default mode network (DMN) are critical for RTV. Given that RTV decreases with growing up, and that boys are likely somewhat behind girls with respect to the network development, we aimed to clarify age and sex effects. Electroencephalogram was recorded during Stroop-like test performance in 124 typically developing children aged 5-12 years. Network fluctuations were calculated as changes of current source density (CSD) in regions of interest (ROIs) from pretest to 1-s test interval. In boys, TPN activation (CSD increase in ROIs included in the TPN) was associated with lower RTV, suggesting a greater engagement of attentional control. In children younger than 9.5 years, higher response stability was associated with the predominance of TPN activation over DMN activation (CSD increase in ROIs included in the TPN > that in the DMN); this predominance increased with age, suggesting that variability among younger children may be due to network immaturity. These findings suggest that the TPN and DMN may play different roles within the network mechanisms of RTV in boys and girls and at different developmental stages.

AB - Intraindividual response time variability (RTV) is considered as a general marker of neurological health. In adults, the central executive and salience networks (task-positive networks, TPN) and the default mode network (DMN) are critical for RTV. Given that RTV decreases with growing up, and that boys are likely somewhat behind girls with respect to the network development, we aimed to clarify age and sex effects. Electroencephalogram was recorded during Stroop-like test performance in 124 typically developing children aged 5-12 years. Network fluctuations were calculated as changes of current source density (CSD) in regions of interest (ROIs) from pretest to 1-s test interval. In boys, TPN activation (CSD increase in ROIs included in the TPN) was associated with lower RTV, suggesting a greater engagement of attentional control. In children younger than 9.5 years, higher response stability was associated with the predominance of TPN activation over DMN activation (CSD increase in ROIs included in the TPN > that in the DMN); this predominance increased with age, suggesting that variability among younger children may be due to network immaturity. These findings suggest that the TPN and DMN may play different roles within the network mechanisms of RTV in boys and girls and at different developmental stages.

KW - Adult

KW - Male

KW - Female

KW - Child

KW - Humans

KW - Reaction Time

KW - Attention/physiology

KW - Magnetic Resonance Imaging/methods

KW - Brain

KW - Nerve Net

KW - Brain Mapping

KW - default network

KW - intraindividual response time variability

KW - children

KW - control networks

KW - sex differences

UR - https://www.scopus.com/record/display.uri?eid=2-s2.0-85152863681&origin=inward&txGid=d4371cba49326e18ee0f397c9ff9f420

UR - https://www.mendeley.com/catalogue/d4bfc6fd-9475-375c-9101-28b9dabd4061/

U2 - 10.1002/dev.22382

DO - 10.1002/dev.22382

M3 - Article

C2 - 37073590

VL - 65

JO - Developmental Psychobiology

JF - Developmental Psychobiology

SN - 0012-1630

IS - 4

M1 - e22382

ER -

ID: 48689298