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Exploring CNS Effects of American Traditional Medicines using Zebrafish Models. / de Abreu, Murilo S.; Costa, Fabiano; Giacomini, Ana C.V.V. et al.

In: Current Neuropharmacology, Vol. 20, No. 3, 03.2022, p. 550-559.

Research output: Contribution to journal › Review article › peer-review

Harvard

de Abreu, MS, Costa, F, Giacomini, ACVV, Demin, KA, Petersen, EV, Rosemberg, DB & Kalueff, AV 2022, 'Exploring CNS Effects of American Traditional Medicines using Zebrafish Models', Current Neuropharmacology, vol. 20, no. 3, pp. 550-559. https://doi.org/10.2174/1570159X19666210712153329

APA

de Abreu, M. S., Costa, F., Giacomini, A. C. V. V., Demin, K. A., Petersen, E. V., Rosemberg, D. B., & Kalueff, A. V. (2022). Exploring CNS Effects of American Traditional Medicines using Zebrafish Models. Current Neuropharmacology, 20(3), 550-559. https://doi.org/10.2174/1570159X19666210712153329

Vancouver

de Abreu MS, Costa F, Giacomini ACVV, Demin KA, Petersen EV, Rosemberg DB et al. Exploring CNS Effects of American Traditional Medicines using Zebrafish Models. Current Neuropharmacology. 2022 Mar;20(3):550-559. doi: 10.2174/1570159X19666210712153329

Author

de Abreu, Murilo S. ; Costa, Fabiano ; Giacomini, Ana C.V.V. et al. / Exploring CNS Effects of American Traditional Medicines using Zebrafish Models. In: Current Neuropharmacology. 2022 ; Vol. 20, No. 3. pp. 550-559.

BibTeX

@article{273567e5cd834b60a666a095b006beb1,
title = "Exploring CNS Effects of American Traditional Medicines using Zebrafish Models",
abstract = "Although American traditional medicine (ATM) has been practiced for millennia, its complex multi-target mechanisms of therapeutic action remain poorly understood. Animal models are widely used to elucidate the therapeutic effects of various ATMs, including their modulation of brain and behavior. Complementing rodent models, the zebrafish (Danio rerio) is a promising novel organism in translational neuroscience and neuropharmacology research. Here, we emphasize the growing value of zebrafish for testing neurotropic effects of ATMs and outline future directions of research in this field. We also demonstrate the developing utility of zebrafish as complementary models for probing CNS mechanisms of ATM action and their potential to treat brain disorders.",
keywords = "American traditional medicine, Animal models, Behavior, Brain effects, Drug screening, Zebrafish, Neurosciences, Animals, Neuropharmacology, Medicine, Traditional, Disease Models, Animal",
author = "{de Abreu}, {Murilo S.} and Fabiano Costa and Giacomini, {Ana C.V.V.} and Demin, {Konstantin A.} and Petersen, {Elena V.} and Rosemberg, {Denis B.} and Kalueff, {Allan V.}",
note = "Funding Information: The study is supported by the Southwest University Zebrafish Platform Construction Funds (Chongqing, China). AVK is the Chair of the International Zebrafish Neurosci-ence Research Consortium (ZNRC) that coordinated this collaborative project. DBR receives the CNPq research productivity grant (process 305051/2018-0) and the FAPERGS {"}Gaucho{"} Researcher Program - PQG fellowship grant (process 19/2551-0001764-2). ACVVG is supported by the FAPERGS research fellowships 19/2551-0001-669-7. The study is partly supported by Sirius University (Sochi, Russia). Research collaboration here is supported by the Russian Science Foundation (RSF) grant 20-65-46006 to Prof. T.G. Amstislavskaya. The funders had no role in the design, analyses, and interpretation of the submitted study or the decision to publish. The study used the facilities and equipment of the Resource Fund of Applied Genetics MIPT (support grant 075-15-2021-684). Publisher Copyright: {\textcopyright} 2022 Bentham Science Publishers.",
year = "2022",
month = mar,
doi = "10.2174/1570159X19666210712153329",
language = "English",
volume = "20",
pages = "550--559",
journal = "Current Neuropharmacology",
issn = "1570-159X",
publisher = "Bentham Science Publishers B.V.",
number = "3",

}

RIS

TY - JOUR

T1 - Exploring CNS Effects of American Traditional Medicines using Zebrafish Models

AU - de Abreu, Murilo S.

AU - Costa, Fabiano

AU - Giacomini, Ana C.V.V.

AU - Demin, Konstantin A.

AU - Petersen, Elena V.

AU - Rosemberg, Denis B.

AU - Kalueff, Allan V.

N1 - Funding Information: The study is supported by the Southwest University Zebrafish Platform Construction Funds (Chongqing, China). AVK is the Chair of the International Zebrafish Neurosci-ence Research Consortium (ZNRC) that coordinated this collaborative project. DBR receives the CNPq research productivity grant (process 305051/2018-0) and the FAPERGS "Gaucho" Researcher Program - PQG fellowship grant (process 19/2551-0001764-2). ACVVG is supported by the FAPERGS research fellowships 19/2551-0001-669-7. The study is partly supported by Sirius University (Sochi, Russia). Research collaboration here is supported by the Russian Science Foundation (RSF) grant 20-65-46006 to Prof. T.G. Amstislavskaya. The funders had no role in the design, analyses, and interpretation of the submitted study or the decision to publish. The study used the facilities and equipment of the Resource Fund of Applied Genetics MIPT (support grant 075-15-2021-684). Publisher Copyright: © 2022 Bentham Science Publishers.

PY - 2022/3

Y1 - 2022/3

N2 - Although American traditional medicine (ATM) has been practiced for millennia, its complex multi-target mechanisms of therapeutic action remain poorly understood. Animal models are widely used to elucidate the therapeutic effects of various ATMs, including their modulation of brain and behavior. Complementing rodent models, the zebrafish (Danio rerio) is a promising novel organism in translational neuroscience and neuropharmacology research. Here, we emphasize the growing value of zebrafish for testing neurotropic effects of ATMs and outline future directions of research in this field. We also demonstrate the developing utility of zebrafish as complementary models for probing CNS mechanisms of ATM action and their potential to treat brain disorders.

AB - Although American traditional medicine (ATM) has been practiced for millennia, its complex multi-target mechanisms of therapeutic action remain poorly understood. Animal models are widely used to elucidate the therapeutic effects of various ATMs, including their modulation of brain and behavior. Complementing rodent models, the zebrafish (Danio rerio) is a promising novel organism in translational neuroscience and neuropharmacology research. Here, we emphasize the growing value of zebrafish for testing neurotropic effects of ATMs and outline future directions of research in this field. We also demonstrate the developing utility of zebrafish as complementary models for probing CNS mechanisms of ATM action and their potential to treat brain disorders.

KW - American traditional medicine

KW - Animal models

KW - Behavior

KW - Brain effects

KW - Drug screening

KW - Zebrafish

KW - Neurosciences

KW - Animals

KW - Neuropharmacology

KW - Medicine, Traditional

KW - Disease Models, Animal

UR - http://www.scopus.com/inward/record.url?scp=85126830478&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/6edb8426-9246-3eeb-a62a-5425988476b1/

U2 - 10.2174/1570159X19666210712153329

DO - 10.2174/1570159X19666210712153329

M3 - Review article

C2 - 34254921

AN - SCOPUS:85126830478

VL - 20

SP - 550

EP - 559

JO - Current Neuropharmacology

JF - Current Neuropharmacology

SN - 1570-159X

IS - 3

ER -

ID: 35770059