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Diverse developmental strategies of x chromosome dosage compensation in eutherian mammals. / Shevchenko, Alexander I.; Dementyeva, Elena V.; Zakharova, Irina S. et al.

In: International Journal of Developmental Biology, Vol. 63, No. 3-5, 01.01.2019, p. 223-233.

Research output: Contribution to journal › Article › peer-review

Harvard

Shevchenko, AI, Dementyeva, EV, Zakharova, IS & Zakian, SM 2019, 'Diverse developmental strategies of x chromosome dosage compensation in eutherian mammals', International Journal of Developmental Biology, vol. 63, no. 3-5, pp. 223-233. https://doi.org/10.1387/ijdb.180376as

APA

Shevchenko, A. I., Dementyeva, E. V., Zakharova, I. S., & Zakian, S. M. (2019). Diverse developmental strategies of x chromosome dosage compensation in eutherian mammals. International Journal of Developmental Biology, 63(3-5), 223-233. https://doi.org/10.1387/ijdb.180376as

Vancouver

Shevchenko AI, Dementyeva EV, Zakharova IS, Zakian SM. Diverse developmental strategies of x chromosome dosage compensation in eutherian mammals. International Journal of Developmental Biology. 2019 Jan 1;63(3-5):223-233. doi: 10.1387/ijdb.180376as

Author

Shevchenko, Alexander I. ; Dementyeva, Elena V. ; Zakharova, Irina S. et al. / Diverse developmental strategies of x chromosome dosage compensation in eutherian mammals. In: International Journal of Developmental Biology. 2019 ; Vol. 63, No. 3-5. pp. 223-233.

BibTeX

@article{53c421b7fd93418da8c9c8247a317434,
title = "Diverse developmental strategies of x chromosome dosage compensation in eutherian mammals",
abstract = "In eutherian mammals, dosage compensation arose to balance X-linked gene expression between sexes and relatively to autosomal gene expression in the evolution of sex chromosomes. Dosage compensation occurs in early mammalian development and comprises X chromosome upregulation and inactivation that are tightly coordinated epigenetic processes. Despite a uniform principle of dosage compensation, mechanisms of X chromosome inactivation and upregulation demonstrate a significant variability depending on sex, developmental stage, cell type, individual, and mammalian species.The review focuses on relationships between X chromosome inactivation and upregulation in mammalian early development.",
keywords = "Dosage compensation, Mammal, X chromosome inactivation, X chromosome upregulation, Xist, MOUSE, LINKED GENES, dosage compensation, ACTIVE X, PLURIPOTENT STEM-CELLS, FACULTATIVE HETEROCHROMATIN, NONCODING RNA, INACTIVATION, mammal, XIST RNA, GENE-EXPRESSION, UP-REGULATION, Pluripotent Stem Cells/cytology, Genomic Imprinting, Epigenesis, Genetic, Male, RNA, Long Noncoding/genetics, Female, Rodentia/embryology, Gene Silencing, Animals, X Chromosome, Up-Regulation/genetics, X Chromosome Inactivation/genetics",
author = "Shevchenko, {Alexander I.} and Dementyeva, {Elena V.} and Zakharova, {Irina S.} and Zakian, {Suren M.}",
year = "2019",
month = jan,
day = "1",
doi = "10.1387/ijdb.180376as",
language = "English",
volume = "63",
pages = "223--233",
journal = "International Journal of Developmental Biology",
issn = "0214-6282",
publisher = "University of the Basque Country Press",
number = "3-5",

}

RIS

TY - JOUR

T1 - Diverse developmental strategies of x chromosome dosage compensation in eutherian mammals

AU - Shevchenko, Alexander I.

AU - Dementyeva, Elena V.

AU - Zakharova, Irina S.

AU - Zakian, Suren M.

PY - 2019/1/1

Y1 - 2019/1/1

N2 - In eutherian mammals, dosage compensation arose to balance X-linked gene expression between sexes and relatively to autosomal gene expression in the evolution of sex chromosomes. Dosage compensation occurs in early mammalian development and comprises X chromosome upregulation and inactivation that are tightly coordinated epigenetic processes. Despite a uniform principle of dosage compensation, mechanisms of X chromosome inactivation and upregulation demonstrate a significant variability depending on sex, developmental stage, cell type, individual, and mammalian species.The review focuses on relationships between X chromosome inactivation and upregulation in mammalian early development.

AB - In eutherian mammals, dosage compensation arose to balance X-linked gene expression between sexes and relatively to autosomal gene expression in the evolution of sex chromosomes. Dosage compensation occurs in early mammalian development and comprises X chromosome upregulation and inactivation that are tightly coordinated epigenetic processes. Despite a uniform principle of dosage compensation, mechanisms of X chromosome inactivation and upregulation demonstrate a significant variability depending on sex, developmental stage, cell type, individual, and mammalian species.The review focuses on relationships between X chromosome inactivation and upregulation in mammalian early development.

KW - Dosage compensation

KW - Mammal

KW - X chromosome inactivation

KW - X chromosome upregulation

KW - Xist

KW - MOUSE

KW - LINKED GENES

KW - dosage compensation

KW - ACTIVE X

KW - PLURIPOTENT STEM-CELLS

KW - FACULTATIVE HETEROCHROMATIN

KW - NONCODING RNA

KW - INACTIVATION

KW - mammal

KW - XIST RNA

KW - GENE-EXPRESSION

KW - UP-REGULATION

KW - Pluripotent Stem Cells/cytology

KW - Genomic Imprinting

KW - Epigenesis, Genetic

KW - Male

KW - RNA, Long Noncoding/genetics

KW - Female

KW - Rodentia/embryology

KW - Gene Silencing

KW - Animals

KW - X Chromosome

KW - Up-Regulation/genetics

KW - X Chromosome Inactivation/genetics

UR - http://www.scopus.com/inward/record.url?scp=85065640174&partnerID=8YFLogxK

U2 - 10.1387/ijdb.180376as

DO - 10.1387/ijdb.180376as

M3 - Article

C2 - 31058299

AN - SCOPUS:85065640174

VL - 63

SP - 223

EP - 233

JO - International Journal of Developmental Biology

JF - International Journal of Developmental Biology

SN - 0214-6282

IS - 3-5

ER -

ID: 20040377