Research output: Contribution to journal › Article › peer-review
Cytokine levels and lipid peroxidation status in blood, follicular fluid, and saliva in women with infertility. / Spirina, L. V.; Romanova, E. A.; Petrov, I. A. et al.
In: Medical News of North Caucasus, Vol. 20, No. 3, 1, 2025, p. 204-209.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - Cytokine levels and lipid peroxidation status in blood, follicular fluid, and saliva in women with infertility
AU - Spirina, L. V.
AU - Romanova, E. A.
AU - Petrov, I. A.
AU - Samoylova, Yu G.
AU - Merkulov, E. D.
N1 - Spirina L. V., Romanova E. A., Petrov I. A., Samoylova Yu. G., Merkulov E. D. Cytokine levels and lipid peroxidation status in blood, follicular fluid, and saliva in women with infertility. Medical News of North Caucasus. 2025;20(3):204-209. DOI – https://doi.org/10.14300/mnnc.2025.20046 (In Russ.)
PY - 2025
Y1 - 2025
N2 - The study focused on the cytokine profile and the lipid peroxidation affecting the embryo quality and the outcome of assisted reproductive technologies. The study involved 32 females diagnosed with infertility who underwent in vitro fertilization treatment (IVF). In order to assess the impact of embryo quality on the outcome, the patients were divided into two groups based on the number of high-quality embryos: Group 1 - less than 3 good and excellent embryos; Group 2 - more than 3 good and excellent embryos. In women with a negative IVF outcome, an increased level of pro-inflammatory cytokines contained in the follicular fluid leads to an increase in the number of good-quality embryos. The accumulation of malondialdehyde in the blood serum women after the involvement of assisted reproductive technologies points at a favorable IVF outcome, this confirming the positive role that oxidative processes have in the embryo development.
AB - The study focused on the cytokine profile and the lipid peroxidation affecting the embryo quality and the outcome of assisted reproductive technologies. The study involved 32 females diagnosed with infertility who underwent in vitro fertilization treatment (IVF). In order to assess the impact of embryo quality on the outcome, the patients were divided into two groups based on the number of high-quality embryos: Group 1 - less than 3 good and excellent embryos; Group 2 - more than 3 good and excellent embryos. In women with a negative IVF outcome, an increased level of pro-inflammatory cytokines contained in the follicular fluid leads to an increase in the number of good-quality embryos. The accumulation of malondialdehyde in the blood serum women after the involvement of assisted reproductive technologies points at a favorable IVF outcome, this confirming the positive role that oxidative processes have in the embryo development.
KW - cytokines
KW - embryo quality
KW - lipid peroxidation
KW - ЦИТОКИНЫ
KW - ПЕРЕКИСНОЕ ОКИСЛЕНИЕ ЛИПИДОВ
KW - КАЧЕСТВО ЭМБРИОНОВ
UR - https://www.scopus.com/pages/publications/105027449112
UR - https://www.elibrary.ru/item.asp?id=84777582
UR - https://www.mendeley.com/catalogue/7693f8a5-55a4-3c69-ac26-a9e59122f82e/
U2 - 10.14300/mnnc.2025.20046
DO - 10.14300/mnnc.2025.20046
M3 - Article
VL - 20
SP - 204
EP - 209
JO - Медицинский вестник Северного Кавказа
JF - Медицинский вестник Северного Кавказа
SN - 2073-8137
IS - 3
M1 - 1
ER -
ID: 74325195