Standard

Cellular imaging by green luminescence of Tb(III)-doped aminomodified silica nanoparticles. / Fedorenko, Svetlana V.; Mustafina, Asiya R.; Mukhametshina, Alsu R. et al.

In: Materials Science and Engineering C, Vol. 76, 01.07.2017, p. 551-558.

Research output: Contribution to journal › Article › peer-review

Harvard

Fedorenko, SV, Mustafina, AR, Mukhametshina, AR, Jilkin, ME, Mukhametzyanov, TA, Solovieva, AO, Pozmogova, TN, Shestopalova, LV, Shestopalov, MA, Kholin, KV, Osin, YN & Sinyashin, OG 2017, 'Cellular imaging by green luminescence of Tb(III)-doped aminomodified silica nanoparticles', Materials Science and Engineering C, vol. 76, pp. 551-558. https://doi.org/10.1016/j.msec.2017.03.106

APA

Fedorenko, S. V., Mustafina, A. R., Mukhametshina, A. R., Jilkin, M. E., Mukhametzyanov, T. A., Solovieva, A. O., Pozmogova, T. N., Shestopalova, L. V., Shestopalov, M. A., Kholin, K. V., Osin, Y. N., & Sinyashin, O. G. (2017). Cellular imaging by green luminescence of Tb(III)-doped aminomodified silica nanoparticles. Materials Science and Engineering C, 76, 551-558. https://doi.org/10.1016/j.msec.2017.03.106

Vancouver

Fedorenko SV, Mustafina AR, Mukhametshina AR, Jilkin ME, Mukhametzyanov TA, Solovieva AO et al. Cellular imaging by green luminescence of Tb(III)-doped aminomodified silica nanoparticles. Materials Science and Engineering C. 2017 Jul 1;76:551-558. doi: 10.1016/j.msec.2017.03.106

Author

Fedorenko, Svetlana V. ; Mustafina, Asiya R. ; Mukhametshina, Alsu R. et al. / Cellular imaging by green luminescence of Tb(III)-doped aminomodified silica nanoparticles. In: Materials Science and Engineering C. 2017 ; Vol. 76. pp. 551-558.

BibTeX

@article{2443406c6bc94684b6a5e0396678859c,
title = "Cellular imaging by green luminescence of Tb(III)-doped aminomodified silica nanoparticles",
abstract = "The work introduces Tb(III)-centered luminescence of amino-modified silica nanoparticles doped with Tb(III) complexes for cellular imaging. For these purposes water-in-oil procedure was optimized for synthesis of 20 and 35 nm luminescent nanoparticles with amino-groups embedded on the surface. The obtained results indicate an impact of the nanoparticle size in decoration, aggregation behavior and luminescent properties of the nanoparticles in protein-based buffer solutions. Formation of a protein-based corona on the nanoparticles surface was revealed through the effect of the nanoparticles on helical superstructure of BSA. This effect is evident from CD spectral data, while no any size impact on the adsorption of BSA onto aminomodified silica surface was observed. Cellular uptake of the nanoparticles studied by confocal and TEM microscopy methods indicates greater cellular uptake for the smaller nanoparticles. Cytotoxicity of the nanoparticles was found to agree well with their cellular uptake behavior, which in turn was found to be greater for the smaller nanoparticles.",
keywords = "Cellular uptake, Cytotoxicity, Lanthanide complex, Luminescence, Protein-corona, Silica nanoparticles, Size-effect, CELLS, SURFACE FUNCTIONALIZATION, SIZE, NANOMATERIALS, IONS, COLLOIDAL STABILITY, INTERNALIZATION, ENERGY-TRANSFER, CYTOTOXICITY, METAL-COMPLEXES, Water, Silicon Dioxide, Metal Nanoparticles",
author = "Fedorenko, {Svetlana V.} and Mustafina, {Asiya R.} and Mukhametshina, {Alsu R.} and Jilkin, {Michail E.} and Mukhametzyanov, {Timur A.} and Solovieva, {Anastasiya O.} and Pozmogova, {Tatiana N.} and Shestopalova, {Lidiya V.} and Shestopalov, {Michael A.} and Kholin, {Kirill V.} and Osin, {Yury N.} and Sinyashin, {Oleg G.}",
note = "Publisher Copyright: {\textcopyright} 2017 Elsevier B.V.",
year = "2017",
month = jul,
day = "1",
doi = "10.1016/j.msec.2017.03.106",
language = "English",
volume = "76",
pages = "551--558",
journal = "Materials Science and Engineering C",
issn = "0928-4931",
publisher = "Elsevier",

}

RIS

TY - JOUR

T1 - Cellular imaging by green luminescence of Tb(III)-doped aminomodified silica nanoparticles

AU - Fedorenko, Svetlana V.

AU - Mustafina, Asiya R.

AU - Mukhametshina, Alsu R.

AU - Jilkin, Michail E.

AU - Mukhametzyanov, Timur A.

AU - Solovieva, Anastasiya O.

AU - Pozmogova, Tatiana N.

AU - Shestopalova, Lidiya V.

AU - Shestopalov, Michael A.

AU - Kholin, Kirill V.

AU - Osin, Yury N.

AU - Sinyashin, Oleg G.

N1 - Publisher Copyright: © 2017 Elsevier B.V.

PY - 2017/7/1

Y1 - 2017/7/1

N2 - The work introduces Tb(III)-centered luminescence of amino-modified silica nanoparticles doped with Tb(III) complexes for cellular imaging. For these purposes water-in-oil procedure was optimized for synthesis of 20 and 35 nm luminescent nanoparticles with amino-groups embedded on the surface. The obtained results indicate an impact of the nanoparticle size in decoration, aggregation behavior and luminescent properties of the nanoparticles in protein-based buffer solutions. Formation of a protein-based corona on the nanoparticles surface was revealed through the effect of the nanoparticles on helical superstructure of BSA. This effect is evident from CD spectral data, while no any size impact on the adsorption of BSA onto aminomodified silica surface was observed. Cellular uptake of the nanoparticles studied by confocal and TEM microscopy methods indicates greater cellular uptake for the smaller nanoparticles. Cytotoxicity of the nanoparticles was found to agree well with their cellular uptake behavior, which in turn was found to be greater for the smaller nanoparticles.

AB - The work introduces Tb(III)-centered luminescence of amino-modified silica nanoparticles doped with Tb(III) complexes for cellular imaging. For these purposes water-in-oil procedure was optimized for synthesis of 20 and 35 nm luminescent nanoparticles with amino-groups embedded on the surface. The obtained results indicate an impact of the nanoparticle size in decoration, aggregation behavior and luminescent properties of the nanoparticles in protein-based buffer solutions. Formation of a protein-based corona on the nanoparticles surface was revealed through the effect of the nanoparticles on helical superstructure of BSA. This effect is evident from CD spectral data, while no any size impact on the adsorption of BSA onto aminomodified silica surface was observed. Cellular uptake of the nanoparticles studied by confocal and TEM microscopy methods indicates greater cellular uptake for the smaller nanoparticles. Cytotoxicity of the nanoparticles was found to agree well with their cellular uptake behavior, which in turn was found to be greater for the smaller nanoparticles.

KW - Cellular uptake

KW - Cytotoxicity

KW - Lanthanide complex

KW - Luminescence

KW - Protein-corona

KW - Silica nanoparticles

KW - Size-effect

KW - CELLS

KW - SURFACE FUNCTIONALIZATION

KW - SIZE

KW - NANOMATERIALS

KW - IONS

KW - COLLOIDAL STABILITY

KW - INTERNALIZATION

KW - ENERGY-TRANSFER

KW - CYTOTOXICITY

KW - METAL-COMPLEXES

KW - Water

KW - Silicon Dioxide

KW - Metal Nanoparticles

UR - http://www.scopus.com/inward/record.url?scp=85015770728&partnerID=8YFLogxK

U2 - 10.1016/j.msec.2017.03.106

DO - 10.1016/j.msec.2017.03.106

M3 - Article

C2 - 28482563

AN - SCOPUS:85015770728

VL - 76

SP - 551

EP - 558

JO - Materials Science and Engineering C

JF - Materials Science and Engineering C

SN - 0928-4931

ER -

ID: 9029412