TY - JOUR

T1 - Beam Shaping Assembly of the VITA Accelerator-Based Neutron Source

AU - Shein, T. V.

AU - Berendeev, E. A.

AU - Degtyarev, V. S.

AU - Koshkarev, A. M.

AU - Kuznetsov, A. S.

AU - Savinov, S. S.

AU - Taskaev, S. Yu

PY - 2025

Y1 - 2025

N2 - The VITA accelerator-based neutron source has been proposed and developed at the Budker Institute of Nuclear Physics (Novosibirsk, Russia) for boron neutron capture therapy (BNCT), which includes a vacuum-insulated tandem accelerator for proton beam production, a lithium target for neutron generation through the 7Li(p, n)7Be reaction, and a neutron beam shaping assembly (BSA) with MgF2 moderator for therapeutic beam generation. This paper presents a comparison of the results of numerical simulations of boron dose and γ-ray dose spatial distributions in a water phantom for three different neutron beam shaping assemblies. The investigations are carried out at the VITA accelerator-based neutron source in the Budker Institute of Nuclear Physics, Siberian branch, Russian Academy of Sciences, using a small neutron detector to measure these components of ionizing radiation. An agreement between the measured and simulated results is obtained. For the VITA accelerator neutron source that was manufactured and is being supplied to the Blokhin National Medical Research Center of Oncology in Moscow with the purpose of conducting clinical trials of the BNCT technique in Russia and the subsequent treatment of patients, the BSA is optimized by numerical simulation with consideration for the equipment, the presence of structural materials, and the wall separating the installation room from the irradiation room. The description of materials that make it possible to form a neutron beam that meets the requirements of the BNCT and the design of manufactured BSA is presented.

AB - The VITA accelerator-based neutron source has been proposed and developed at the Budker Institute of Nuclear Physics (Novosibirsk, Russia) for boron neutron capture therapy (BNCT), which includes a vacuum-insulated tandem accelerator for proton beam production, a lithium target for neutron generation through the 7Li(p, n)7Be reaction, and a neutron beam shaping assembly (BSA) with MgF2 moderator for therapeutic beam generation. This paper presents a comparison of the results of numerical simulations of boron dose and γ-ray dose spatial distributions in a water phantom for three different neutron beam shaping assemblies. The investigations are carried out at the VITA accelerator-based neutron source in the Budker Institute of Nuclear Physics, Siberian branch, Russian Academy of Sciences, using a small neutron detector to measure these components of ionizing radiation. An agreement between the measured and simulated results is obtained. For the VITA accelerator neutron source that was manufactured and is being supplied to the Blokhin National Medical Research Center of Oncology in Moscow with the purpose of conducting clinical trials of the BNCT technique in Russia and the subsequent treatment of patients, the BSA is optimized by numerical simulation with consideration for the equipment, the presence of structural materials, and the wall separating the installation room from the irradiation room. The description of materials that make it possible to form a neutron beam that meets the requirements of the BNCT and the design of manufactured BSA is presented.

UR - https://www.mendeley.com/catalogue/524c462b-3e85-30a4-8815-12b164659167/

UR - https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=105012971471&origin=inward

U2 - 10.1134/S1547477125700700

DO - 10.1134/S1547477125700700

M3 - Article

VL - 22

SP - 842

EP - 846

JO - Physics of Particles and Nuclei Letters

JF - Physics of Particles and Nuclei Letters

SN - 1547-4771

IS - 4

ER -