Research output: Contribution to journal › Article › peer-review
Ant13 Encodes Regulatory Factor WD40 Controlling Anthocyanin and Proanthocyanidin Synthesis in Barley (Hordeum vulgare L.). / Shoeva, Olesya Yu; Mukhanova, Marina A; Zakhrabekova, Shakhira et al.
In: Journal of agricultural and food chemistry, Vol. 71, No. 18, 10.05.2023, p. 6967-6977.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Ant13 Encodes Regulatory Factor WD40 Controlling Anthocyanin and Proanthocyanidin Synthesis in Barley (Hordeum vulgare L.)
AU - Shoeva, Olesya Yu
AU - Mukhanova, Marina A
AU - Zakhrabekova, Shakhira
AU - Hansson, Mats
N1 - Funding: The study was partially supported by ICG (project FWNR2022-0017), the Kurchatov Center for Genomic Research at the Institute of Cytology and Genetics (project no. 075-15-2019-1662), the Swedish Institute Visby Programme (25896/ 2018), the Swedish Research Council (VR 2018-05117), the Swedish Research Council for Environment, Agricultural Sciences, and Spatial Planning (FORMAS 2018-01026), the Erik Philip-Sörensen Foundation, and the Royal Physiographic Society in Lund.
PY - 2023/5/10
Y1 - 2023/5/10
N2 - Flavonoid compounds like anthocyanins and proanthocyanidins are important plant secondary metabolites having wide biological activities for humans. In this study, the molecular function of the Ant13 locus, which is one of the key loci governing flavonoid synthesis in barley, was determined. It was found that Ant13 encodes a WD40-type regulatory protein, which is required for transcriptional activation of a set of structural genes encoding enzymes of flavonoid biosynthesis at the leaf sheath base (colored by anthocyanins) and in grains (which accumulate proanthocyanidins). Besides its role in flavonoid biosynthesis, pleiotropic effects of this gene in plant growth were revealed. The mutants deficient in the Ant13 locus showed similar germination rates but a decreased rate of root and shoot growth and yield-related parameters in comparison to the parental cultivars. This is the seventh Ant locus (among 30) for which molecular functions in flavonoid biosynthesis regulation have been determined.
AB - Flavonoid compounds like anthocyanins and proanthocyanidins are important plant secondary metabolites having wide biological activities for humans. In this study, the molecular function of the Ant13 locus, which is one of the key loci governing flavonoid synthesis in barley, was determined. It was found that Ant13 encodes a WD40-type regulatory protein, which is required for transcriptional activation of a set of structural genes encoding enzymes of flavonoid biosynthesis at the leaf sheath base (colored by anthocyanins) and in grains (which accumulate proanthocyanidins). Besides its role in flavonoid biosynthesis, pleiotropic effects of this gene in plant growth were revealed. The mutants deficient in the Ant13 locus showed similar germination rates but a decreased rate of root and shoot growth and yield-related parameters in comparison to the parental cultivars. This is the seventh Ant locus (among 30) for which molecular functions in flavonoid biosynthesis regulation have been determined.
KW - anthocyanin-less
KW - condensed tannin
KW - flavonoid
KW - haze
KW - malt
KW - regulatory gene
KW - Proanthocyanidins/metabolism
KW - Humans
KW - Transcription Factors/genetics
KW - Hordeum/genetics
KW - Plant Proteins/genetics
KW - Flavonoids/metabolism
KW - Gene Expression Regulation, Plant
KW - Anthocyanins/metabolism
UR - https://www.scopus.com/record/display.uri?eid=2-s2.0-85156274033&origin=inward&txGid=1c47623a5b6b2e831a699a26d34ef0aa
UR - https://www.mendeley.com/catalogue/1efb4022-d8ce-3319-b2bc-4830f44a7202/
U2 - 10.1021/acs.jafc.2c09051
DO - 10.1021/acs.jafc.2c09051
M3 - Article
C2 - 37104658
VL - 71
SP - 6967
EP - 6977
JO - Journal of agricultural and food chemistry
JF - Journal of agricultural and food chemistry
SN - 0021-8561
IS - 18
ER -
ID: 48879667