Research output: Contribution to journal › Article › peer-review
Amperometric glucose biosensing performance of a novel graphene nanoplatelets-iron phthalocyanine incorporated conducting hydrogel. / Al-Sagur, H.; Shanmuga sundaram, Komathi; Kaya, E. N. et al.
In: Biosensors and Bioelectronics, Vol. 139, 111323, 15.08.2019, p. 111323.Research output: Contribution to journal › Article › peer-review
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TY - JOUR
T1 - Amperometric glucose biosensing performance of a novel graphene nanoplatelets-iron phthalocyanine incorporated conducting hydrogel
AU - Al-Sagur, H.
AU - Shanmuga sundaram, Komathi
AU - Kaya, E. N.
AU - Durmuş, M.
AU - Basova, T. V.
AU - Hassan, A.
N1 - Publisher Copyright: © 2019 Elsevier B.V.
PY - 2019/8/15
Y1 - 2019/8/15
N2 - Herein, a novel one step synthesis of multicomponent three dimensional polyacrylic acid (PAA) based conducting hydrogel (CH) incorporated with iron phthalocyanine functionalised graphene nanoplatelets (GPL-FePc) is reported. An amperometric glucose biosensor was fabricated by the immobilization of glucose oxidase (GOx) onto the synthesised PAA-VS-PANI/GPL-FePc-CH (where VS-PANI is vinyl substituted polyaniline). Scanning electron microscopy reveals the presence of three dimensional microporous structure with estimated pore size of 19 μm. The 5-(trifluoromethyl)-2-mercaptopyridine substitution onto FePc enabled the solubility of FePc in water and controls the aggregation of GPL-FePc in the synthesised CH. A sharp peak around 699 nm in UV–visible spectra confirms the presence of incorporated GPL-FePc into CH. Cyclic voltammogram of the synthesised CH biosensor exhibited well defined redox peaks with a ΔE p value of 0.26 V in Fe(CN) 6 3-/4- bench mark solution. The fabricated PAA-VS-PANI/GPL-FePc/GO x -CH amperometric biosensor resulted in remarkable detection sensitivity of 18.11 μA mM −1 cm −2 with an average response time of ∼1 s, linearity from 1 to 20 mM, and low detection limit of 6.4 μM for the determination of glucose.
AB - Herein, a novel one step synthesis of multicomponent three dimensional polyacrylic acid (PAA) based conducting hydrogel (CH) incorporated with iron phthalocyanine functionalised graphene nanoplatelets (GPL-FePc) is reported. An amperometric glucose biosensor was fabricated by the immobilization of glucose oxidase (GOx) onto the synthesised PAA-VS-PANI/GPL-FePc-CH (where VS-PANI is vinyl substituted polyaniline). Scanning electron microscopy reveals the presence of three dimensional microporous structure with estimated pore size of 19 μm. The 5-(trifluoromethyl)-2-mercaptopyridine substitution onto FePc enabled the solubility of FePc in water and controls the aggregation of GPL-FePc in the synthesised CH. A sharp peak around 699 nm in UV–visible spectra confirms the presence of incorporated GPL-FePc into CH. Cyclic voltammogram of the synthesised CH biosensor exhibited well defined redox peaks with a ΔE p value of 0.26 V in Fe(CN) 6 3-/4- bench mark solution. The fabricated PAA-VS-PANI/GPL-FePc/GO x -CH amperometric biosensor resulted in remarkable detection sensitivity of 18.11 μA mM −1 cm −2 with an average response time of ∼1 s, linearity from 1 to 20 mM, and low detection limit of 6.4 μM for the determination of glucose.
KW - Conducting hydrogel
KW - Glucose biosensor
KW - Graphene nanoplatelets (GPL)
KW - Water-soluble iron phthalocyanine
KW - MODIFIED ELECTRODES
KW - COBALT PHTHALOCYANINE
KW - SENSOR
KW - SENSING PLATFORM
KW - WALLED CARBON NANOTUBES
KW - MECHANICAL-PROPERTIES
KW - IMMOBILIZATION
KW - ELECTROCHEMICAL DETECTION
KW - OXIDASE
KW - FABRICATION
UR - http://www.scopus.com/inward/record.url?scp=85065791835&partnerID=8YFLogxK
U2 - 10.1016/j.bios.2019.111323
DO - 10.1016/j.bios.2019.111323
M3 - Article
C2 - 31121437
AN - SCOPUS:85065791835
VL - 139
SP - 111323
JO - Biosensors and Bioelectronics
JF - Biosensors and Bioelectronics
SN - 0956-5663
M1 - 111323
ER -
ID: 20045410