Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Research › peer-review
Air flow and precipitation of medicine aerosol droplets in the human bronchial tree. / Medvedev, A. E.; Gafurova, P. S.
International Conference on the Methods of Aerophysical Research, ICMAR 2020. ed. / Vasily M. Fomin; Alexander Shiplyuk. American Institute of Physics Inc., 2021. 030018 (AIP Conference Proceedings; Vol. 2351).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Research › peer-review
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TY - GEN
T1 - Air flow and precipitation of medicine aerosol droplets in the human bronchial tree
AU - Medvedev, A. E.
AU - Gafurova, P. S.
N1 - Funding Information: The study was supported by the Russian Foundation for Basic Research and the Subject of the Russian Federation (Novosibirsk Region) within the framework of the research project No. 19-41-540003 p_a. Publisher Copyright: © 2021 Author(s). Copyright: Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/5/24
Y1 - 2021/5/24
N2 - The work is devoted to the calculation of gas flow and modeling of droplet sedimentation of medicinal aerosols in human lungs. To solve this problem, a previously constructed three-dimensional model of a human bronchial tree was used. For calculation of gas flow in lungs and aerosol deposition the method of step-by-step calculation of the flow in bronchial tree was used. It allowed to calculate the air flow and aerosol droplets deposition in all bronchial branches up to alveolus. Human breathing was calculated using COVID-19 thermal helium-oxygen mixture treatment method. Breathing with a thermal helium-oxygen mixture requires less effort from the patient than breathing with air. Three-dimensional numerical calculations of air flow and aerosol droplets in human lungs have been performed. The characteristics of a serial medical nebulizer were used to calculate the deposition of aerosol droplets. It is shown that the number of past droplets depends (except for flow, droplet size) on the duration of breath. The nebulizer under consideration does not provide delivery of medicines to the lung alveolus.
AB - The work is devoted to the calculation of gas flow and modeling of droplet sedimentation of medicinal aerosols in human lungs. To solve this problem, a previously constructed three-dimensional model of a human bronchial tree was used. For calculation of gas flow in lungs and aerosol deposition the method of step-by-step calculation of the flow in bronchial tree was used. It allowed to calculate the air flow and aerosol droplets deposition in all bronchial branches up to alveolus. Human breathing was calculated using COVID-19 thermal helium-oxygen mixture treatment method. Breathing with a thermal helium-oxygen mixture requires less effort from the patient than breathing with air. Three-dimensional numerical calculations of air flow and aerosol droplets in human lungs have been performed. The characteristics of a serial medical nebulizer were used to calculate the deposition of aerosol droplets. It is shown that the number of past droplets depends (except for flow, droplet size) on the duration of breath. The nebulizer under consideration does not provide delivery of medicines to the lung alveolus.
UR - http://www.scopus.com/inward/record.url?scp=85107182271&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/db01b5c5-f09e-3c9d-8420-95d11bc34e36/
U2 - 10.1063/5.0051724
DO - 10.1063/5.0051724
M3 - Conference contribution
AN - SCOPUS:85107182271
SN - 9780735440999
T3 - AIP Conference Proceedings
BT - International Conference on the Methods of Aerophysical Research, ICMAR 2020
A2 - Fomin, Vasily M.
A2 - Shiplyuk, Alexander
PB - American Institute of Physics Inc.
T2 - 20th International Conference on the Methods of Aerophysical Research, ICMAR 2020
Y2 - 1 November 2020 through 7 November 2020
ER -
ID: 28876538