Research output: Contribution to journal › Article › peer-review
2,6-Disubstituted 4-azidopyrimidines : synthesis, kinetic and thermodynamic studies of azide-tetrazole rearrangement by NMR spectroscopy. / Pleshkova, N. V.; Nikolaenkova, E. B.; Krivopalov, V. P. et al.
In: Russian Chemical Bulletin, Vol. 66, No. 11, 01.11.2017, p. 2095-2102.Research output: Contribution to journal › Article › peer-review
}
TY - JOUR
T1 - 2,6-Disubstituted 4-azidopyrimidines
T2 - synthesis, kinetic and thermodynamic studies of azide-tetrazole rearrangement by NMR spectroscopy
AU - Pleshkova, N. V.
AU - Nikolaenkova, E. B.
AU - Krivopalov, V. P.
AU - Mamatyuk, V. I.
N1 - Publisher Copyright: © 2017, Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2017/11/1
Y1 - 2017/11/1
N2 - Thermodynamic and kinetic parameters of the tautomeric tetrazole-azide rearrangement for a series of 2,6-disubstituted 4-azidopyrimidines are determined by NOESY/EXSY and DNMR: ΔH = 15—28 kJ mol–1; ΔS = 47—65 J mol–1 К–1; Еa = 93—117 kJ mol–1; lgA = 15.1—18.9. They are dependent on electronic properties of the substituents and the polarity of solvent.
AB - Thermodynamic and kinetic parameters of the tautomeric tetrazole-azide rearrangement for a series of 2,6-disubstituted 4-azidopyrimidines are determined by NOESY/EXSY and DNMR: ΔH = 15—28 kJ mol–1; ΔS = 47—65 J mol–1 К–1; Еa = 93—117 kJ mol–1; lgA = 15.1—18.9. They are dependent on electronic properties of the substituents and the polarity of solvent.
KW - 4-azidopyrimidine
KW - Arrhenius equation
KW - azide-tetrazole equilibrium
KW - DNMR
KW - enthalpy
KW - entropy
KW - NMR
KW - NOESY/EXSY
KW - rate constant
KW - tetrazolo[c]pyrimidines
KW - SERIES
KW - 2-AZIDOPYRIMIDINES
KW - ISOMERIZATION
KW - H-1-N-15
KW - COUPLING-CONSTANTS
KW - AROMATICITY
KW - HETEROCYCLES
KW - SYSTEMS
KW - TAUTOMERISM
KW - AZIDE/TETRAZOLE EQUILIBRIUM
UR - http://www.scopus.com/inward/record.url?scp=85043980194&partnerID=8YFLogxK
U2 - 10.1007/s11172-017-1986-2
DO - 10.1007/s11172-017-1986-2
M3 - Article
AN - SCOPUS:85043980194
VL - 66
SP - 2095
EP - 2102
JO - Russian Chemical Bulletin
JF - Russian Chemical Bulletin
SN - 1066-5285
IS - 11
ER -
ID: 12179254