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  1. 2020

  2. PARPs’ impact on base excision DNA repair

    Lavrik, O. I., Sept 2020, In: DNA Repair. 93, 6 p., 102911.

    Research output: Contribution to journal › Review article › peer-review

  3. Usnic Acid Conjugates with Monoterpenoids as Potent Tyrosyl-DNA Phosphodiesterase 1 Inhibitors

    Luzina, O., Filimonov, A., Zakharenko, A., Chepanova, A., Zakharova, O., Ilina, E., Dyrkheeva, N., Likhatskaya, G., Salakhutdinov, N. & Lavrik, O., 28 Aug 2020, In: Journal of Natural Products. 83, 8, p. 2320-2329 10 p.

    Research output: Contribution to journal › Article › peer-review

  4. Inhibition of tyrosyl-DNA phosphodiesterase 1 by lipophilic pyrimidine nucleosides

    Zakharenko, A. L., Drenichev, M. S., Dyrkheeva, N. S., Ivanov, G. A., Oslovsky, V. E., Ilina, E. S., Chernyshova, I. A., Lavrik, O. I. & Mikhailov, S. N., 13 Aug 2020, In: Molecules. 25, 16, 13 p., 3694.

    Research output: Contribution to journal › Article › peer-review

  5. Design, Synthesis, and Biological Investigation of Novel Classes of 3-Carene-Derived Potent Inhibitors of TDP1

    Il'ina, I. V., Dyrkheeva, N. S., Zakharenko, A. L., Sidorenko, A. Y., Li-Zhulanov, N. S., Korchagina, D. V., Chand, R., Ayine-Tora, D. M., Chepanova, A. A., Zakharova, O. D., Ilina, E. S., Reynisson, J., Malakhova, A. A., Medvedev, S. P., Zakian, S. M., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., Aug 2020, In: Molecules (Basel, Switzerland). 25, 15, 22 p., 3496.

    Research output: Contribution to journal › Article › peer-review

  6. Characterization of the Altai Maral Chymosin Gene, Production of a Chymosin Recombinant Analog in the Prokaryotic Expression System, and Analysis of Its Several Biochemical Properties

    Belenkaya, S. V., Bondar, A. A., Kurgina, T. A., Elchaninov, V. V., Bakulina, A. Y., Rukhlova, E. A., Lavrik, O. I., Ilyichev, A. A. & Shcherbakov, D. N., 1 Jul 2020, In: Biochemistry (Moscow). 85, 7, p. 781-791 11 p.

    Research output: Contribution to journal › Article › peer-review

  7. 1,1’-(Гексан-1,6-диил)бис(3-(((1R,4aS,10aR)-7-изопропил-1,4a-диметил-1,2,3,4,4a,9,10,10a-октагидрофенантрен-1-ил)метил)мочевина, проявляющая ингибирующее действие в отношении фермента тирозил-ДНК-фосфодиэстеразы 1 человека и увеличивающая активность темозоломида в отношении клеток глиобластомы

    Ковалева, К. С., Олешко, О. С., Яровая, О. И., Мамонтова, Е. М., Захаренко, А. Л., Захарова, О. Д., Чересиз, С. В., Покровский, А. Г., Лаврик, О. И. & Салахутдинов, Н. Ф., 26 Jun 2020, IPC No. C07C275/24, A61K31/17, A61P35/00, Роспатент - Федеральная служба по интеллектуальной собственности, Patent No. 2724882, Priority date 28 Nov 2019, Priority No. 2019138671

    Research output: Patent › Patent for invention

  8. Non-canonical interaction of DNA repair proteins with intact and cleaved AP sites

    Khodyreva, S. & Lavrik, O., 1 Jun 2020, In: DNA Repair. 90, 15 p., 102847.

    Research output: Contribution to journal › Review article › peer-review

  9. Impact of PARP1, PARP2 & PARP3 on the Base Excision Repair of Nucleosomal DNA

    Kutuzov, M. M., Belousova, E. A., Ilina, E. S. & Lavrik, O. I., 8 May 2020, Mechanisms of Genome Protection and Repair. Zharkov, D. O. (ed.). Springer, Vol. 1241. p. 47-57 11 p. (Advances in experimental medicine and biology).

    Research output: Chapter in Book/Report/Conference proceeding › Chapter › Research › peer-review

  10. Functional role of N-terminal extension of human ap endonuclease 1 in coordination of base excision dna repair via protein–protein interactions

    Moor, N., Vasil’eva, I. & Lavrik, O., 28 Apr 2020, In: International Journal of Molecular Sciences. 21, 9, 18 p., 3122.

    Research output: Contribution to journal › Article › peer-review

  11. Effect of Human XRCC1 Protein Oxidation on the Functional Activity of Its Complexes with the Key Enzymes of DNA Base Excision Repair

    Vasil’eva, I. A., Moor, N. A. & Lavrik, O. I., 22 Mar 2020, In: Biochemistry (Moscow). 85, 3, p. 288-299 12 p.

    Research output: Contribution to journal › Article › peer-review

  12. Photoreactive DNA as a Tool to Study Replication Protein A Functioning in DNA Replication and Repair

    Rechkunova, N. I. & Lavrik, O. I., 1 Mar 2020, In: Photochemistry and Photobiology. 96, 2, p. 440-449 10 p.

    Research output: Contribution to journal › Review article › peer-review

  13. Molecular mechanisms of PARP-1 inhibitor 7-methylguanine

    Nilov, D., Maluchenko, N., Kurgina, T., Pushkarev, S., Lys, A., Kutuzov, M., Gerasimova, N., Feofanov, A., Švedas, V., Lavrik, O. & Studitsky, V. M., Mar 2020, In: International Journal of Molecular Sciences. 21, 6, 11 p., 2159.

    Research output: Contribution to journal › Article › peer-review

  14. Design, Synthesis and Molecular Modeling Study of Conjugates of ADP and Morpholino Nucleosides as A Novel Class of Inhibitors of PARP-1, PARP-2 and PARP-3

    Sherstyuk, Y. V., Ivanisenko, N. V., Zakharenko, A. L., Sukhanova, M. V., Peshkov, R. Y., Eltsov, I. V., Kutuzov, M. M., Kurgina, T. A., Belousova, E. A., Ivanisenko, V. A., Lavrik, O. I., Silnikov, V. N. & Abramova, T. V., 1 Jan 2020, In: International Journal of Molecular Sciences. 21, 1, 25 p., 214.

    Research output: Contribution to journal › Article › peer-review

  15. Identification of novel inhibitors for the tyrosyl-DNA-phosphodiesterase 1 (Tdp1) mutant SCAN1 using virtual screening

    Mamontova, E. M., Zakharenko, A. L., Zakharova, O. D., Dyrkheeva, N. S., Volcho, K. P., Reynisson, J., Arabshahi, H. J., Salakhutdinov, N. F. & Lavrik, O. I., 1 Jan 2020, In: Bioorganic and Medicinal Chemistry. 28, 1, 11 p., 115234.

    Research output: Contribution to journal › Article › peer-review

  16. Promising new inhibitors of tyrosyl-DNA phosphodiesterase I (Tdp 1) combining 4- arylcoumarin and monoterpenoid moieties as components of complex antitumor therapy

    Khomenko, T. M., Zakharenko, A. L., Chepanova, A. A., Ilina, E. S., Zakharova, O. D., Kaledin, V. I., Nikolin, V. P., Popova, N. A., Korchagina, D. V., Reynisson, J., Chand, R., Ayine-tora, D. M., Patel, J., Leung, I. K. H., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., 1 Jan 2020, In: International Journal of Molecular Sciences. 21, 1, 21 p., 126.

    Research output: Contribution to journal › Article › peer-review

  17. Naked mole rat cells display more efficient DNA excision repair and higher resistance to toxic impacts than mouse cells

    Evdokimov, A., Petruseva, I., Popov, A., Koval, O. & Lavrik, O., 2020, INTERNATIONAL CONFERENCE LONGEVITY INTERVENTIONS 2020 (ICLI 2020). Kovtun, O. & Bazarnyi (eds.). University of Lueneburg, Department of Economics and Social Sciences, Research Institute on Professions, 6 p. 01017. (BIO Web of Conferences; vol. 22).

    Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › Research › peer-review

  18. 2019

  19. Effective Inhibitors of Tyrosyl-DNA Phosphodiesterase 1 Based on Monoterpenoids as Potential Agents for Antitumor Therapy

    Chepanova, A. A., Li-Zhulanov, N. S., Sukhikh, A. S., Zafar, A., Reynisson, J., Zakharenko, A. L., Zakharova, O. D., Korchagina, D. V., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., 1 Nov 2019, In: Russian Journal of Bioorganic Chemistry. 45, 6, p. 647-655 9 p.

    Research output: Contribution to journal › Article › peer-review

  20. New hydrazinothiazole derivatives of usnic acid as potent TDP1 inhibitors

    Filimonov, A. S., Chepanova, A. A., Luzina, O. A., Zakharenko, A. L., Zakharova, O. D., Ilina, E. S., Dyrkheeva, N. S., Kuprushkin, M. S., Kolotaev, A. V., Khachatryan, D. S., Patel, J., Leung, I. K. H., Chand, R., Ayine-Tora, D. M., Reynisson, J., Volcho, K. P., Salakhutdinov, N. F. & Lavrik, O. I., 15 Oct 2019, In: Molecules. 24, 20, 3711.

    Research output: Contribution to journal › Article › peer-review

  21. Double-Stranded DNA Fragments Bearing Unrepairable Lesions and Their Internalization into Mouse Krebs-2 Carcinoma Cells

    Dolgova, E. V., Evdokimov, A. N., Proskurina, A. S., Efremov, Y. R., Bayborodin, S. I., Potter, E. A., Popov, A. A., Petruseva, I. O., Lavrik, O. I. & Bogachev, S. S., 1 Oct 2019, In: Nucleic Acid Therapeutics. 29, 5, p. 278-290 13 p.

    Research output: Contribution to journal › Article › peer-review

  22. Dehydroabietylamine Ureas and Thioureas as Tyrosyl-DNA Phosphodiesterase 1 Inhibitors That Enhance the Antitumor Effect of Temozolomide on Glioblastoma Cells

    Kovaleva, K., Oleshko, O., Mamontova, E., Yarovaya, O., Zakharova, O., Zakharenko, A., Kononova, A., Dyrkheeva, N., Cheresiz, S., Pokrovsky, A., Lavrik, O. & Salakhutdinov, N., 27 Sept 2019, In: Journal of Natural Products. 82, 9, p. 2443-2450 8 p.

    Research output: Contribution to journal › Article › peer-review

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