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  1. 2024

  2. Sulfide, Sulfoxide, and Sulfone Derivatives of Usnic Acid as Inhibitors of Human TDP1 and TDP2 Enzymes

    Filimonov, A. S., Mikhailova, M. A., Dyrkheeva, N. S., Chernyshova, I. A., Kornienko, T. E., Naumenko, K. A., Anarbaev, R. O., Nefedov, A. A., Achara, C., Curtis, A. D. M., Luzina, O. A., Volcho, K. P., Salakhutdinov, N. F., Lavrik, O. I. & Reynisson, J., 17 Dec 2024, In: Chemistry (Switzerland). 6, 6, p. 1658-1679 22 p.

    Research output: Contribution to journal › Article › peer-review

  3. Proteins Associated with Neurodegenerative Diseases: Link to DNA Repair

    Khodyreva, S. N., Dyrkheeva, N. S. & Lavrik, O. I., 11 Dec 2024, In: Biomedicines. 12, 12, 2808.

    Research output: Contribution to journal › Article › peer-review

  4. Apurinic/apyrimidinic endonuclease 1 has major impact in prevention of suicidal covalent DNA–protein crosslink with apurinic/apyrimidinic site in cellular extracts

    Lebedeva, N. A., Dyrkheeva, N. S., Rechkunova, N. I. & Lavrik, O. I., Nov 2024, In: IUBMB Life. 76, 11, p. 987-996 10 p.

    Research output: Contribution to journal › Article › peer-review

  5. Novel Peptide–Drug Conjugates with Dual Anticancer Activity

    O’Flaherty, S., Luzina, O. A., Dyrkheeva, N. S., Krier, Y., Leprince, J., Zakharenko, A. L., Pokrovsky, M. A., Pokrovsky, A. G., Lavrik, O. I., Salakhutdinov, N. F., Varbanov, M., Devocelle, M. & Volcho, K. P., Nov 2024, In: International Journal of Molecular Sciences. 25, 22, 12411.

    Research output: Contribution to journal › Article › peer-review

  6. A Knockout of Poly(ADP-Ribose) Polymerase 1 in a Human Cell Line: An Influence on Base Excision Repair Reactions in Cellular Extracts

    Khodyreva, S. N., Ilina, E. S., Dyrkheeva, N. S., Kochetkova, A. S., Yamskikh, A. A., Maltseva, E. A., Malakhova, A. A., Medvedev, S. P., Zakian, S. M. & Lavrik, O. I., Feb 2024, In: Cells. 13, 4, 302.

    Research output: Contribution to journal › Article › peer-review

  7. 2023

  8. Pharmacokinetic study of Tdp1 inhibitor resulted in a significant increase in antitumor effect in the treatment of Lewis lung carcinoma in mice by its combination with topotecan

    Okhina, A. A., Kornienko, T. E., Rogachev, A. D., Luzina, O. A., Popova, N. A., Nikolin, V. P., Zakharenko, A. L., Dyrkheeva, N. S., Pokrovsky, A. G., Salakhutdinov, N. F. & Lavrik, O. I., 30 Nov 2023, In: Journal of Pharmaceutical and Biomedical Analysis. 236, 9 p., 115731.

    Research output: Contribution to journal › Article › peer-review

  9. Cas9 is mostly orthogonal to human systems of DNA break sensing and repair

    Maltseva, E. A., Vasil'eva, I. A., Moor, N. A., Kim, D. V., Dyrkheeva, N. S., Kutuzov, M. M., Vokhtantsev, I. P., Kulishova, L. M., Zharkov, D. O. & Lavrik, O. I., 29 Nov 2023, In: PLoS ONE. 18, 11, 26 p., e0294683.

    Research output: Contribution to journal › Article › peer-review

  10. Effect of Usnic Acid-Derived Tyrosyl-DNA Phosphodiesterase 1 Inhibitor Used as Monotherapy or in Combination with Olaparib on Transplanted Tumors In Vivo

    Kornienko, T. E., Zakharenko, A. L., Ilina, E. S., Chepanova, A. A., Zakharova, O. D., Dyrkheeva, N. S., Popova, N. A., Nikolin, V. P., Filimonov, A. S., Luzina, O. A., Salakhutdinov, N. F. & Lavrik, O. I., Apr 2023, In: Molecular Biology. 57, 2, p. 214-224 11 p.

    Research output: Contribution to journal › Article › peer-review

  11. Transcriptomic Analysis of CRISPR/Cas9-Mediated PARP1-Knockout Cells under the Influence of Topotecan and TDP1 Inhibitor

    Dyrkheeva, N. S., Malakhova, A. A., Zakharenko, A. L., Okorokova, L. S., Shtokalo, D. N., Pavlova, S. V., Medvedev, S. P., Zakian, S. M., Nushtaeva, A. A., Tupikin, A. E., Kabilov, M. R., Khodyreva, S. N., Luzina, O. A., Salakhutdinov, N. F. & Lavrik, O. I., 7 Mar 2023, In: International Journal of Molecular Sciences. 24, 6, 5148.

    Research output: Contribution to journal › Article › peer-review

  12. Влияние производного усниновой кислоты (ингибитора тирозил-ДНК-фосфодиэстеразы 1) на трансплантированные опухоли in vivo в качестве монотерапии и в сочетании с олапарибом

    Kornienko, T. E., Zakharenko, A. L., Ilina, E. S., Chepanova, A. A., Zakharova, O. D., Dyrkheeva, N. S., Popova, N. A., Nikolin, V. P., Filimonov, A. S., Luzina, O. A., Salakhutdinov, N. F. & Lavrik, O. I., 1 Mar 2023, In: Molekuliarnaia biologiia. 57, 2, p. 220-231 12 p., 8.

    Research output: Contribution to journal › Article › peer-review

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