Tissue distribution of OL9-116, a Tdp1 inhibitor based on usnic acid, is significantly altered in Lewis lung carcinoma-bearing mice compared to healthy animals

Original language	English
Article number	117054
Pages (from-to)	117054
Number of pages	8
Journal	Journal of Pharmaceutical and Biomedical Analysis
Volume	265
DOIs	https://doi.org/10.1016/j.jpba.2025.117054
Publication status	Published - 15 Nov 2025

LC[sbnd]MS/MS, QuEChERS methodology, Tdp1 inhibitor, Tissue homogenate, Usnic acid, Lung/metabolism, Chromatography, Liquid/methods, Benzofurans/pharmacokinetics, Tandem Mass Spectrometry/methods, Mice, Inbred C57BL, Male, Tissue Distribution, Animals, Liver/metabolism, Mice, Carcinoma, Lewis Lung/drug therapy

ID: 68546146