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  1. 2012

  2. НАНОКОМПОЗИТЫ ДИОКСИДА ТИТАНА ДЛЯ ИНАКТИВАЦИИ ВИРУСНОГО ГЕНОМА ВНУТРИ КЛЕТОК, СПОСОБ ИХ ПОЛУЧЕНИЯ

    Исмагилов, З. Р., Шикина, Н. В., Гаврилова, А. А., Пармон, В. Н., Зарытова, В. Ф., Левина, А. С., Репкова, М. Н., Беланов, Е. Ф., Зиновьев, В. В., Малыгин, Э. Г., Загребельный, С. Н., Нетёсов, С. В., Байбородин, С. И. & Евдокимов, А. А., 10 Mar 2012, IPC No. C12N15/11, B82B3/00, A61K48/00, Роспатент - Федеральная служба по интеллектуальной собственности, Patent No. 2444571, Priority date 28 May 2008, Priority No. 2008121609

    Research output: Patent › Patent for invention

  3. 2013

  4. НАНОКОМПОЗИТ С АКТИВНЫМ ЛИГАНДОМ, СПОСОБ ЕГО ПРИГОТОВЛЕНИЯ И СПОСОБ АДРЕСНОЙ ИНАКТИВАЦИИ ВИРУСА ГРИППА ВНУТРИ КЛЕТКИ

    Исмагилов, З. Р., Левина, А. С., Репкова, М. Н., Шикина, Н. В., Зарытова, В. Ф., Загребельный, С. Н. & Мазуркова, Н. А., 27 Oct 2013, IPC No. C12N15/11, B82B3/00, C12N7/04, Роспатент - Федеральная служба по интеллектуальной собственности, Patent No. 2496878, Priority date 4 May 2012, Priority No. 2012118712

    Research output: Patent › Patent for invention

  5. СПОСОБ ПОЛУЧЕНИЯ НАНОРАЗМЕРНОЙ СИСТЕМЫ ДОСТАВКИ ФРАГМЕНТОВ НУКЛЕИНОВЫХ КИСЛОТ И ИХ АНАЛОГОВ В КЛЕТКИ МЛЕКОПИТАЮЩИХ

    Зарытова, В. Ф., Левина, А. С., Репкова, М. Н., Исмагилов, З. Р. & Шикина, Н. В., 20 Nov 2013, IPC No. C12N15/00, B82B3/00, Роспатент - Федеральная служба по интеллектуальной собственности, Patent No. 2499045, Priority date 5 Mar 2012, Priority No. 2012108259

    Research output: Patent › Patent for invention

  6. 2017

  7. Effects of brain reninangiotensin system inhibition in ISIAH rats with inherited stress-induced arterial hypertension

    Klimov, L. O., Ryazanova, M. A., Fedoseeva, L. A. & Markel, A. L., 2017, In: Вавиловский журнал генетики и селекции. 21, 6, p. 735-741 7 p.

    Research output: Contribution to journal › Article › peer-review

  8. Correlated target search by uracil-DNA glycosylase in the presence of bulky adducts and DNA-binding ligands

    Mechetin, G. V., Dyatlova, E. A., Sinyakov, A. N., Ryabinin, V. A., Vorobjev, P. E. & Zharkov, D. O., 1 Jan 2017, In: Russian Journal of Bioorganic Chemistry. 43, 1, p. 23-28 6 p.

    Research output: Contribution to journal › Article › peer-review

  9. Dihydroartemisinin counteracts fibrotic portal hypertension via farnesoid X receptor-dependent inhibition of hepatic stellate cell contraction

    Endutkin, A., Popov, A., Yudkina, A., Makasheva, K., Afonnikov, D., Simmerling, C. & Zharkov, D., 1 Jan 2017, In: FEBS Journal. 284, 1, p. 114-133 20 p.

    Research output: Contribution to journal › Article › peer-review

  10. Solid/gas biocatalysis

    Kulishova, L. M. & Zharkov, D. O., 1 Feb 2017, In: Biochemistry (Moscow). 82, 2, p. 95-105 11 p.

    Research output: Contribution to journal › Review article › peer-review

  11. DNA Deformation-Coupled Recognition of 8-Oxoguanine: Conformational Kinetic Gating in Human DNA Glycosylase

    Li, H., Endutkin, A. V., Bergonzo, C., Fu, L., Grollman, A., Zharkov, D. O. & Simmerling, C., 22 Feb 2017, In: Journal of the American Chemical Society. 139, 7, p. 2682-2692 11 p.

    Research output: Contribution to journal › Article › peer-review

  12. Toward gene therapy of hypertension: Experimental study on hypertensive ISIAH rats

    Repkova, M. N., Levina, A. S., Seryapina, A. A., Shikina, N. V., Bessudnova, E. V., Zarytova, V. F. & Markel, A. L., 1 Apr 2017, In: Biochemistry (Moscow). 82, 4, p. 454-457 4 p.

    Research output: Contribution to journal › Article › peer-review

  13. Recognition but no repair of abasic site in single-stranded DNA by human ribosomal uS3 protein residing within intact 40S subunit

    Grosheva, A. S., Zharkov, D. O., Stahl, J., Gopanenko, A. V., Tupikin, A. E., Kabilov, M. R., Graifer, D. M. & Karpova, G. G., 20 Apr 2017, In: Nucleic Acids Research. 45, 7, p. 3833-3843 11 p.

    Research output: Contribution to journal › Article › peer-review

  14. Molecular dynamics simulation of the opposite-base preference and interactions in the active site of formamidopyrimidine-DNA glycosylase

    Popov, A. V., Endutkin, A. V., Vorobjev, Y. N. & Zharkov, D. O., 8 May 2017, In: BMC Structural Biology. 17, 1, p. 1-19 19 p., 5.

    Research output: Contribution to journal › Article › peer-review

  15. Aberrant base excision repair pathway of oxidatively damaged DNA: Implications for degenerative diseases

    Talhaoui, I., Matkarimov, B. T., Tchenio, T., Zharkov, D. O. & Saparbaev, M. K., 1 Jun 2017, In: Free Radical Biology and Medicine. 107, p. 266-277 12 p.

    Research output: Contribution to journal › Review article › peer-review

  16. Impact of delivery method on antiviral activity of phosphodiester, phosphorothioate, and phosphoryl guanidine oligonucleotides in MDCK cells infected with H5N1 bird flu virus

    Levina, A. S., Repkova, M. N., Chelobanov, B. P., Bessudnova, E. V., Mazurkova, N. A., Stetsenko, D. A. & Zarytova, V. F., 1 Jul 2017, In: Molecular Biology. 51, 4, p. 633-638 6 p.

    Research output: Contribution to journal › Article › peer-review

  17. Impact of Delivery Method on Antiviral Activity of Phosphodiester, Phosphorothioate, and Phosphoryl Guanidine Oligonucleotides in MDCK Cells Infected with H5N1 Bird Flu Virus

    Levina, A. S., Repkova, M. N., Chelobanov, B. P., Bessudnova, E. V., Mazurkova, N. A., Stetsenko, D. A. & Zarytova, V. F., 1 Jul 2017, In: Molekuliarnaia biologiia. 51, 4, p. 717-723 7 p.

    Research output: Contribution to journal › Article › peer-review

  18. Influence of pyridine-like ligands on the structure, photochemical and biological properties of nitro-nitrosyl ruthenium complexes

    Kostin, G. A., Mikhailov, A. A., Kuratieva, N. V., Pischur, D. P., Zharkov, D. O. & Grin, I. R., 7 Aug 2017, In: New Journal of Chemistry. 41, 15, p. 7758-7765 8 p.

    Research output: Contribution to journal › Article › peer-review

  19. Dynamic recognition in protein-DNA complexes

    Simmerling, C., Grollman, A. & Zharkov, D., 20 Aug 2017, In: Abstracts of papers of the american chemical society. 254, 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  20. DNA repair in transcription intermediates by helix-two-turn-helix family DNA glycosylases

    Makasheva, K. & Zharkov, D., Sept 2017, In: FEBS Journal. 284, p. 114-114 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  21. Enzyme processivity as a drug target: The case of poxvirus uracil-DNA glycosylase

    Zharkov, D., Sept 2017, In: FEBS Journal. 284, p. 11-11 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  22. Nuclear delivery of oligonucleotides via nanocomposites based on TiO2 nanoparticles and polylysine

    Chelobanov, B. P., Repkova, M. N., Baiborodin, S. I., Ryabchikova, E. I. & Stetsenko, D. A., 1 Sept 2017, In: Molecular Biology. 51, 5, p. 695-704 10 p.

    Research output: Contribution to journal › Article › peer-review

  23. Global DNA dynamics of 8-oxoguanine repair by human OGG1 revealed by stopped-flow kinetics and molecular dynamics simulation

    Lukina, M. V., Koval, V. V., Lomzov, A. A., Zharkov, D. O. & Fedorova, O. S., 1 Oct 2017, In: Molecular BioSystems. 13, 10, p. 1954-1966 13 p.

    Research output: Contribution to journal › Article › peer-review

  24. Nuclear delivery of oligonucleotides via nanocomposites based on TiO2 nanoparticles and polylysine

    Chelobanov, B. P., Repkova, M. N., Baiborodin, S. I., Ryabchikova, E. I. & Stetsenko, D. A., 9 Nov 2017, In: Molekuliarnaia biologiia. 51, 5, p. 797-808 12 p.

    Research output: Contribution to journal › Article › peer-review

  25. 2018

  26. Альтернативные доноры генетической информации при генной коррекции: олигонуклеотиды и РНК

    Торгашева, Н. А. & Жарков, Д. О., 2018, Редактирование генов и геномов. Новосибирск: ФГУП "Издательство СО РАН", Vol. 1. p. 295-316 22 p.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter › Research › peer-review

  27. Перспективы применения системы CRISPR/Cas9 в терапии

    Грин, И. Р. & Власов, В. В., 2018, Редактирование генов и геномов. Новосибирск: ФГУП "Издательство СО РАН", Vol. 2. p. 275-305 31 p.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter › Research › peer-review

  28. Редактирование эпигенетических меток ДНК

    Петрова, Д. В., Жарков, Д. О. & Грин, И. Р., 2018, Редактирование генов и геномов. Новосибирск: ФГУП "Издательство СО РАН", Vol. 1. p. 317-353 37 p.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter › Research › peer-review

  29. Структурные основы специфичности белка Cas9

    Вохтанцев, И. П., Ким, Д. В. & Жарков, Д. О., 2018, Редактирование генов и геномов. Новосибирск: ФГУП "Издательство СО РАН", Vol. 1. p. 177-198 22 p.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter › Research › peer-review

  30. Узнавание и процессинг двуцепочечных разрывов в клетках бактерий и эукариот

    Мечетин, Г. В. & Жарков, Д. О., 2018, Редактирование генов и геномов. Новосибирск: ФГУП "Издательство СО РАН", Vol. 1. p. 267-293 27 p.

    Research output: Chapter in Book/Report/Conference proceeding › Chapter › Research › peer-review

  31. Antisense oligonucleotides for the arterial hypertension mechanisms study and therapy

    Klimov, L. O., Seryapina, A. A., Zarytova, V. F., Levina, A. S. & Markel, A. L., 1 Jan 2018, In: Вавиловский журнал генетики и селекции. 22, 2, p. 240-247 8 p.

    Research output: Contribution to journal › Review article › peer-review

  32. 2',3'-Dideoxyuridine triphosphate conjugated to SiO2 nanoparticles: Synthesis and evaluation of antiproliferative activity

    Vasilyeva, S. V., Grin, I. R., Chelobanov, B. P. & Stetsenko, D. A., 15 Apr 2018, In: Bioorganic and Medicinal Chemistry Letters. 28, 7, p. 1248-1251 4 p.

    Research output: Contribution to journal › Article › peer-review

  33. Variable termination sites of DNA polymerases encountering a DNA–protein cross-link

    Yudkina, A. V., Dvornikova, A. P. & Zharkov, D. O., 1 Jun 2018, In: PLoS ONE. 13, 6, p. e0198480 17 p., 0198480.

    Research output: Contribution to journal › Article › peer-review

  34. Not only the active site: importance of remote interactions in the recognition of oxidative DNA lesions

    Zharkov, D., Jul 2018, In: FEBS Open Bio. 8, p. 139-140 2 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  35. Characterization of primary normal and malignant breast cancer cell and their response to chemotherapy and immunostimulatory agents

    Nushtaeva, A. A., Stepanov, G. A., Semenov, D. V., Juravlev, E. S., Balahonova, E. A., Gerasimov, A. V., Sidorov, S. V., Savelyev, E. I., Kuligina, E. V., Richter, V. A. & Koval, O. A., 9 Jul 2018, In: BMC Cancer. 18, 1, p. 728 11 p., 728.

    Research output: Contribution to journal › Article › peer-review

  36. Characterization of biochemical properties of an apurinic/apyrimidinic endonuclease from Helicobacter pylori

    Turgimbayeva, A., Abeldenov, S., Zharkov, D. O., Ishchenko, A. A., Ramankulov, Y., Saparbaev, M. & Khassenov, B., 15 Aug 2018, In: PLoS ONE. 13, 8, p. e0202232 26 p., e0202232.

    Research output: Contribution to journal › Article › peer-review

  37. Residue coevolution reveals functionally important intramolecular interactions in formamidopyrimidine-DNA glycosylase

    Endutkin, A. V., Koptelov, S. S., Popov, A. V., Torgasheva, N. A., Lomzov, A. A., Tsygankova, A. R., Skiba, T. V., Afonnikov, D. A. & Zharkov, D. O., 1 Sept 2018, In: DNA Repair. 69, p. 24-33 10 p.

    Research output: Contribution to journal › Article › peer-review

  38. Methods of the synthesis of silicon-containing nanoparticles intended for nucleic acid delivery

    Levina, A. S., Repkova, M. N., Ismagilov, Z. R. & Zarytova, V. F., 7 Sept 2018, In: Eurasian Chemico-Technological Journal. 20, 3, p. 177-194 18 p.

    Research output: Contribution to journal › Article › peer-review

  39. Non-agglomerated silicon-organic nanoparticles and their nanocomplexes with oligonucleotides: Synthesis and properties

    Levina, A. S., Repkova, M. N., Shikina, N. V., Ismagilov, Z. R., Yashnik, S. A., Semenov, D. V., Savinovskaya, Y. I., Mazurkova, N. A., Pyshnaya, I. A. & Zarytova, V. F., 21 Sept 2018, In: Beilstein Journal of Nanotechnology. 9, 1, p. 2516-2525 10 p.

    Research output: Contribution to journal › Article › peer-review

  40. ANTISENSE CONTAINING NANOCOMPOSITES IN HYPERTENSION TREATMENT IN ISIAH RATS

    Klimov, L., Ryazanova, M., Levina, A. & Markel, A., Oct 2018, In: Journal of Hypertension. 36, p. E18-E18 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  41. NANOCOMPOSITE (SI-ODN-II), CONTAINING ANTISENSE OLIGONUCLEOTIDES TARGETED TO MRNA OF THE BETA-1-ADRENORECEPTORS FOR HYPERTENSION THERAPY IN RATS WITH STRESS-SENSITIVE ARTERIAL HYPERTENSION (ISIAH RATS)

    Ryazanova, M., Klimov, L., Seryapina, A., Zarytova, V., Repkova, M., Levina, A. & Markel, A., Oct 2018, In: Journal of Hypertension. 36, p. E81-E82 2 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  42. Nucleotide modifications decrease innate immune response induced by synthetic analogs of snRNAs and snoRNAs

    Stepanov, G., Zhuravlev, E., Shender, V., Nushtaeva, A., Balakhonova, E., Mozhaeva, E., Kasakin, M., Koval, V., Lomzov, A., Pavlyukov, M., Malyants, I., Zhorov, M., Kabilova, T., Chernolovskaya, E., Govorun, V., Kuligina, E., Semenov, D. & Richter, V., 2 Nov 2018, In: Genes. 9, 11, 18 p., 531.

    Research output: Contribution to journal › Article › peer-review

  43. Oxidative damage to epigenetically methylated sites affects DNA stability, dynamics and enzymatic demethylation

    Gruber, D. R., Toner, J. J., Miears, H. L., Shernyukov, A. V., Kiryutin, A. S., Lomzov, A. A., Endutkin, A. V., Grin, I. R., Petrova, D. V., Kupryushkin, M. S., Yurkovskaya, A. V., Johnson, E. C., Okon, M., Bagryanskaya, E. G., Zharkov, D. O. & Smirnov, S. L., 16 Nov 2018, In: Nucleic Acids Research. 46, 20, p. 10827-10839 13 p.

    Research output: Contribution to journal › Article › peer-review

  44. Brain as a potential target for antisense oligonucleotide treatment of hypertensive disease. Experimental study on the hypertensive ISIAH rat strain

    Levina, A. S., Zarytova, V. F., Repkova, M. N., Klimov, O. L., Seryapina, A. A., Shikina, N. V., Shevelev, O. B. & Markel, A. L., Dec 2018, In: Basic and Clinical Pharmacology and Toxicology. 124, p. 6-7 2 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  45. Aberrant repair initiated by the adenine-DNA glycosylase does not play a role in UV-induced mutagenesis in Escherichia coli

    Zutterling, C., Mursalimov, A., Talhaoui, I., Koshenov, Z., Akishev, Z., Bissenbaev, A. K., Mazon, G., Geacintov, N. E., Gasparutto, D., Groisman, R., Zharkov, D. O., Matkarimov, B. T. & Saparbaev, M., 5 Dec 2018, In: PeerJ. 6, 12, 23 p., 6029.

    Research output: Contribution to journal › Article › peer-review

  46. 2019

  47. abstract OR-3: Fleeting ensembles: Transient protein-protein interactions in DNA repair

    Жарков, Д. О., 2019, In: International Journal of Biomedicine. 9, S1, p. 6-7 2 p.

    Research output: Contribution to journal › Conference article › peer-review

  48. Base Excision DNA Repair Deficient Cells: From Disease Models to Genotoxicity Sensors

    Kim, D. V., Makarova, A. V., Miftakhova, R. R. & Zharkov, D. O., 1 Jan 2019, In: Current Pharmaceutical Design. 25, 3, p. 298-312 15 p.

    Research output: Contribution to journal › Review article › peer-review

  49. Observations on Protecting Groups in the Synthesis of Mono- and Triphosphates of Amino Alcohols

    Sherstyuk, Y. V., Chalova, P. V., Silnikov, V. N. & Abramova, T. V., 4 Mar 2019, In: Organic Preparations and Procedures International. 51, 2, p. 182-191 10 p.

    Research output: Contribution to journal › Article › peer-review

  50. Conformational Dynamics of Damage Processing by Human DNA Glycosylase NEIL1

    Kladova, O. A., Grin, I. R., Fedorova, O. S., Kuznetsov, N. A. & Zharkov, D. O., 15 Mar 2019, In: Journal of Molecular Biology. 431, 6, p. 1098-1112 15 p.

    Research output: Contribution to journal › Article › peer-review

  51. Reading and misreading 8-oxoguanine, a paradigmatic ambiguous nucleobase

    Yudkina, A. V., Shilkin, E. S., Endutkin, A. V., Makarova, A. V. & Zharkov, D. O., 1 May 2019, In: Crystals. 9, 5, 31 p., 269.

    Research output: Contribution to journal › Article › peer-review

  52. Antisense Oligonucleotides Immobilized on Silicon-Organic Nanoparticles as a Tool for Prolonged Correction of Hypertensive States

    Levina, A. S., Repkova, M. N., Klimov, L. O., Ryazanova, M. A., Markel, A. L. & Zarytova, V. F., 15 May 2019, In: Bulletin of Experimental Biology and Medicine. 167, 1, p. 116-119 4 p.

    Research output: Contribution to journal › Article › peer-review

  53. Critical Sites of DNA Backbone Integrity for Damaged Base Removal by Formamidopyrimidine-DNA Glycosylase

    Endutkin, A. V. & Zharkov, D. O., 18 Jun 2019, In: Biochemistry. 58, 24, p. 2740-2749 10 p.

    Research output: Contribution to journal › Article › peer-review

  54. Development of constructs based on the CRISPR/Cas9 system for studying the role of non-canonical mismatch repair in editing the epigenome

    Kakhkharova, Z. I., Khantakova, D. V., Petrova, D. V. & Grin, I. R., Jul 2019, In: FEBS Open Bio. 9, p. 399-399 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

  55. DNA lesions against genome editing: how Cas9 cleaves the substrates with damages

    Vokhtantsev, I. P., Endutkin, A. V., Kulishova, L. M. & Zharkov, O., Jul 2019, In: FEBS Open Bio. 9, p. 397-397 1 p.

    Research output: Contribution to journal › Meeting Abstract › peer-review

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