Global DNA dynamics of 8-oxoguanine repair by human OGG1 revealed by stopped-flow kinetics and molecular dynamics simulation

RESONANCE ENERGY-TRANSFER, BASE-EXCISION-REPAIR, NUCLEIC-ACIDS, ACTIVE-SITE, BIOCHEMICAL EXPLORATION, SUBSTRATE RECOGNITION, DAMAGE RECOGNITION, LESION RECOGNITION, GENERALIZED BORN, GLYCOSYLASE, DNA Damage/genetics, Humans, Substrate Specificity, DNA Repair/genetics, Molecular Dynamics Simulation, Guanine/analogs & derivatives, DNA/chemistry, Protein Binding, DNA Glycosylases/metabolism, Kinetics

ID: 8672787