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Water-Soluble Polyoxometal Clusters of Molybdenum (V) with Pyrazole and Triazole: Synthesis and Study of Cytotoxicity and Antiviral Activity. / Konkova, Anna V; Savina, Iulia V; Evtushok, Darya V и др.

в: Molecules (Basel, Switzerland), Том 28, № 24, 8079, 12.2023.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Konkova, AV, Savina, IV, Evtushok, DV, Pozmogova, TN, Solomatina, MV, Nokhova, AR, Alekseev, AY, Kuratieva, NV, Eltsov, IV, Yanshole, VV, Shestopalov, AM, Ivanov, AA & Shestopalov, MA 2023, 'Water-Soluble Polyoxometal Clusters of Molybdenum (V) with Pyrazole and Triazole: Synthesis and Study of Cytotoxicity and Antiviral Activity', Molecules (Basel, Switzerland), Том. 28, № 24, 8079. https://doi.org/10.3390/molecules28248079

APA

Konkova, A. V., Savina, I. V., Evtushok, D. V., Pozmogova, T. N., Solomatina, M. V., Nokhova, A. R., Alekseev, A. Y., Kuratieva, N. V., Eltsov, I. V., Yanshole, V. V., Shestopalov, A. M., Ivanov, A. A., & Shestopalov, M. A. (2023). Water-Soluble Polyoxometal Clusters of Molybdenum (V) with Pyrazole and Triazole: Synthesis and Study of Cytotoxicity and Antiviral Activity. Molecules (Basel, Switzerland), 28(24), [8079]. https://doi.org/10.3390/molecules28248079

Vancouver

Konkova AV, Savina IV, Evtushok DV, Pozmogova TN, Solomatina MV, Nokhova AR и др. Water-Soluble Polyoxometal Clusters of Molybdenum (V) with Pyrazole and Triazole: Synthesis and Study of Cytotoxicity and Antiviral Activity. Molecules (Basel, Switzerland). 2023 дек.;28(24):8079. doi: 10.3390/molecules28248079

Author

Konkova, Anna V ; Savina, Iulia V ; Evtushok, Darya V и др. / Water-Soluble Polyoxometal Clusters of Molybdenum (V) with Pyrazole and Triazole: Synthesis and Study of Cytotoxicity and Antiviral Activity. в: Molecules (Basel, Switzerland). 2023 ; Том 28, № 24.

BibTeX

@article{767aef9f8e6c4b38b84cff22be2873b4,
title = "Water-Soluble Polyoxometal Clusters of Molybdenum (V) with Pyrazole and Triazole: Synthesis and Study of Cytotoxicity and Antiviral Activity",
abstract = "Among well-studied and actively developing compounds are polyoxometalates (POMs), which show application in many fields. Extending this class of compounds, we introduce a new subclass of polyoxometal clusters (POMCs) [Mo12O28(μ-L)8]4- (L = pyrazolate (pz) or triazolate (1,2,3-trz or 1,2,4-trz)), structurally similar to POM, but containing binuclear Mo2O4 clusters linked by bridging oxo- and organic ligands. The complexes obtained by ampoule synthesis from the binuclear cluster [Mo2O4(C2O4)2(H2O)2]2- in a melt of an organic ligand are soluble and stable in aqueous solutions. In addition to the detailed characterization in solid state and in aqueous solution, the biological properties of the compounds on normal and cancer cells were investigated, and antiviral activity against influenza A virus (subtype H5N1) was demonstrated.",
keywords = "Water, Models, Molecular, Molybdenum/pharmacology, Influenza A Virus, H5N1 Subtype, Triazoles/pharmacology, Pyrazoles/pharmacology, Antiviral Agents/pharmacology",
author = "Konkova, {Anna V} and Savina, {Iulia V} and Evtushok, {Darya V} and Pozmogova, {Tatiana N} and Solomatina, {Maria V} and Nokhova, {Alina R} and Alekseev, {Alexander Y} and Kuratieva, {Natalia V} and Eltsov, {Ilia V} and Yanshole, {Vadim V} and Shestopalov, {Aleksander M} and Ivanov, {Anton A} and Shestopalov, {Michael A}",
note = "This research was funded by the Russian Science Foundation (No. 22-23-00660).",
year = "2023",
month = dec,
doi = "10.3390/molecules28248079",
language = "English",
volume = "28",
journal = "Molecules",
issn = "1420-3049",
publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",
number = "24",

}

RIS

TY - JOUR

T1 - Water-Soluble Polyoxometal Clusters of Molybdenum (V) with Pyrazole and Triazole: Synthesis and Study of Cytotoxicity and Antiviral Activity

AU - Konkova, Anna V

AU - Savina, Iulia V

AU - Evtushok, Darya V

AU - Pozmogova, Tatiana N

AU - Solomatina, Maria V

AU - Nokhova, Alina R

AU - Alekseev, Alexander Y

AU - Kuratieva, Natalia V

AU - Eltsov, Ilia V

AU - Yanshole, Vadim V

AU - Shestopalov, Aleksander M

AU - Ivanov, Anton A

AU - Shestopalov, Michael A

N1 - This research was funded by the Russian Science Foundation (No. 22-23-00660).

PY - 2023/12

Y1 - 2023/12

N2 - Among well-studied and actively developing compounds are polyoxometalates (POMs), which show application in many fields. Extending this class of compounds, we introduce a new subclass of polyoxometal clusters (POMCs) [Mo12O28(μ-L)8]4- (L = pyrazolate (pz) or triazolate (1,2,3-trz or 1,2,4-trz)), structurally similar to POM, but containing binuclear Mo2O4 clusters linked by bridging oxo- and organic ligands. The complexes obtained by ampoule synthesis from the binuclear cluster [Mo2O4(C2O4)2(H2O)2]2- in a melt of an organic ligand are soluble and stable in aqueous solutions. In addition to the detailed characterization in solid state and in aqueous solution, the biological properties of the compounds on normal and cancer cells were investigated, and antiviral activity against influenza A virus (subtype H5N1) was demonstrated.

AB - Among well-studied and actively developing compounds are polyoxometalates (POMs), which show application in many fields. Extending this class of compounds, we introduce a new subclass of polyoxometal clusters (POMCs) [Mo12O28(μ-L)8]4- (L = pyrazolate (pz) or triazolate (1,2,3-trz or 1,2,4-trz)), structurally similar to POM, but containing binuclear Mo2O4 clusters linked by bridging oxo- and organic ligands. The complexes obtained by ampoule synthesis from the binuclear cluster [Mo2O4(C2O4)2(H2O)2]2- in a melt of an organic ligand are soluble and stable in aqueous solutions. In addition to the detailed characterization in solid state and in aqueous solution, the biological properties of the compounds on normal and cancer cells were investigated, and antiviral activity against influenza A virus (subtype H5N1) was demonstrated.

KW - Water

KW - Models, Molecular

KW - Molybdenum/pharmacology

KW - Influenza A Virus, H5N1 Subtype

KW - Triazoles/pharmacology

KW - Pyrazoles/pharmacology

KW - Antiviral Agents/pharmacology

UR - https://www.scopus.com/record/display.uri?eid=2-s2.0-85180695113&origin=inward&txGid=beeecf3d37eeb4a2076653c73127cdca

U2 - 10.3390/molecules28248079

DO - 10.3390/molecules28248079

M3 - Article

C2 - 38138569

VL - 28

JO - Molecules

JF - Molecules

SN - 1420-3049

IS - 24

M1 - 8079

ER -

ID: 59536789