Результаты исследований: Научные публикации в периодических изданиях › обзорная статья › Рецензирование
Volatile and Intravenous Anesthetics for Brain Protection in Cardiac Surgery: Does the Choice of Anesthesia Matter? / Lomivorotov, Vladimir V.; Moroz, Gleb; Abubakirov, Marat и др.
в: Journal of Cardiothoracic and Vascular Anesthesia, Том 36, № 2, 02.2022, стр. 567-576.Результаты исследований: Научные публикации в периодических изданиях › обзорная статья › Рецензирование
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TY - JOUR
T1 - Volatile and Intravenous Anesthetics for Brain Protection in Cardiac Surgery: Does the Choice of Anesthesia Matter?
AU - Lomivorotov, Vladimir V.
AU - Moroz, Gleb
AU - Abubakirov, Marat
AU - Osinsky, Roman
AU - Landoni, Giovanni
N1 - Publisher Copyright: © 2021 Elsevier Inc.
PY - 2022/2
Y1 - 2022/2
N2 - Postoperative neurologic complications have a significant effect on morbidity, mortality, and long-term disability in patients undergoing cardiac surgery. The etiology of brain injury in patients undergoing cardiac surgery is multifactorial and remains unclear. There are several perioperative causative factors for neurologic complications, including microembolization, hypoperfusion, and systemic inflammatory response syndrome. Despite technologic advances and the development of new anesthetic drugs, there remains a high rate of postoperative neurologic complications. Moreover, despite the strong evidence that volatile anesthesia exerts cardioprotective effects in patients undergoing cardiac surgery, the neuroprotective effects of volatile agents remain unclear. Several studies have reported an association of using volatile anesthetics with improvement of biochemical markers of brain injury and postoperative neurocognitive function. However, there is a need for additional studies to define the optimal anesthetic drug for protecting the brain in patients undergoing cardiac surgery.
AB - Postoperative neurologic complications have a significant effect on morbidity, mortality, and long-term disability in patients undergoing cardiac surgery. The etiology of brain injury in patients undergoing cardiac surgery is multifactorial and remains unclear. There are several perioperative causative factors for neurologic complications, including microembolization, hypoperfusion, and systemic inflammatory response syndrome. Despite technologic advances and the development of new anesthetic drugs, there remains a high rate of postoperative neurologic complications. Moreover, despite the strong evidence that volatile anesthesia exerts cardioprotective effects in patients undergoing cardiac surgery, the neuroprotective effects of volatile agents remain unclear. Several studies have reported an association of using volatile anesthetics with improvement of biochemical markers of brain injury and postoperative neurocognitive function. However, there is a need for additional studies to define the optimal anesthetic drug for protecting the brain in patients undergoing cardiac surgery.
KW - brain protection
KW - cardiopulmonary bypass
KW - neurologic complications
KW - volatile anesthetics
UR - http://www.scopus.com/inward/record.url?scp=85103079626&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/6846ef28-baf2-3e04-9ac1-c56d6ea2e642/
U2 - 10.1053/j.jvca.2021.02.048
DO - 10.1053/j.jvca.2021.02.048
M3 - Review article
C2 - 33766470
AN - SCOPUS:85103079626
VL - 36
SP - 567
EP - 576
JO - Journal of Cardiothoracic and Vascular Anesthesia
JF - Journal of Cardiothoracic and Vascular Anesthesia
SN - 1053-0770
IS - 2
ER -
ID: 28203480