Результаты исследований: Публикации в книгах, отчётах, сборниках, трудах конференций › статья в сборнике материалов конференции › научная › Рецензирование
Verification of a Beam of Epithermal Neutrons for Boron-Neutron Capture Therapy. / Verkhovod, G. D.; Kasatov, D. A.; Kolesnikov, Ia A. и др.
27th Russian Particle Accelerator Conference, RuPAC 2021. ред. / Maksim Kuzin; Volker R W Schaa. CERN, 2021. стр. 199-201 MOPSA47 (CERN-Proceedings; Том 2021-September).Результаты исследований: Публикации в книгах, отчётах, сборниках, трудах конференций › статья в сборнике материалов конференции › научная › Рецензирование
}
TY - GEN
T1 - Verification of a Beam of Epithermal Neutrons for Boron-Neutron Capture Therapy
AU - Verkhovod, G. D.
AU - Kasatov, D. A.
AU - Kolesnikov, Ia A.
AU - Koshkarev, A.
AU - Makarov, A. N.
AU - Shchudlo, I. M.
AU - Sycheva, T. V.
AU - Savinov, S. S.
AU - Taskaev, S. Yu
N1 - Funding Information: Work supported by Russian Science Foundation, grant No. 19-72-30005. g.verkhovod@alumni.nsu.ru Publisher Copyright: © 27th Russian Particle Accelerator Conference, RuPAC 2021. All rights reserved.
PY - 2021
Y1 - 2021
N2 - A promising method of treatment of many malignant tumors is the boron neutron capture therapy (BNCT). It provides a selective destruction of tumor cells by prior accumulation of a stable boron-10 isotope inside them and subsequent irradiation with epithermal neutrons. As a result of absorption of a neutron by boron, a nuclear reaction occurs with the release of energy in a cell containing boron. To measure the "boron" dose, a small-size neutron detector based on a boron-enriched cast polystyrene scintillator was proposed and developed at the BINP. The paper presents the results of changing the boron dose and the dose of gamma radiation in a water phantom and the comparison of these results with the calculated ones. The obtained result is important for irradiation of small laboratory animals with grafted tumors, large domestic animals with spontaneous tumors, and the planned clinical trials of the technique.
AB - A promising method of treatment of many malignant tumors is the boron neutron capture therapy (BNCT). It provides a selective destruction of tumor cells by prior accumulation of a stable boron-10 isotope inside them and subsequent irradiation with epithermal neutrons. As a result of absorption of a neutron by boron, a nuclear reaction occurs with the release of energy in a cell containing boron. To measure the "boron" dose, a small-size neutron detector based on a boron-enriched cast polystyrene scintillator was proposed and developed at the BINP. The paper presents the results of changing the boron dose and the dose of gamma radiation in a water phantom and the comparison of these results with the calculated ones. The obtained result is important for irradiation of small laboratory animals with grafted tumors, large domestic animals with spontaneous tumors, and the planned clinical trials of the technique.
UR - http://www.scopus.com/inward/record.url?scp=85130344543&partnerID=8YFLogxK
UR - https://www.mendeley.com/catalogue/53449186-4b53-3fde-b575-adf1378d9693/
U2 - 10.18429/JACoW-RuPAC2021-MOPSA47
DO - 10.18429/JACoW-RuPAC2021-MOPSA47
M3 - Conference contribution
AN - SCOPUS:85130344543
SN - 9783954502400
T3 - CERN-Proceedings
SP - 199
EP - 201
BT - 27th Russian Particle Accelerator Conference, RuPAC 2021
A2 - Kuzin, Maksim
A2 - Schaa, Volker R W
PB - CERN
T2 - 27th Russian Particle Accelerator Conference, RuPAC 2021
Y2 - 27 September 2021 through 1 October 2021
ER -
ID: 36162749