Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Varicose vein disease in the context of insulin resistance. / Korolenya, Valeria; Filipenko, Maxim; Smetanina, Mariya.
в: Vessel Plus, Том 8, 36, 2024.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
}
TY - JOUR
T1 - Varicose vein disease in the context of insulin resistance
AU - Korolenya, Valeria
AU - Filipenko, Maxim
AU - Smetanina, Mariya
N1 - This work was supported by the Program of Fundamental Scientific Research of the Russian Federation (PFSR RF) “Fundamental Basics of Health Preservation” (No. 121031300045-2).
PY - 2024
Y1 - 2024
N2 - The prevalence of insulin resistance (IR) is growing every year, which determines the risks of developing type 2 diabetes and cardiovascular diseases. Currently, IR is not recognized as a risk factor for the development of varicose veins (VVs), but the connection between the two is tacitly obvious because obesity and diabetes are risk factors for VVs. In this review, we have attempted to highlight the common nature of these two conditions in the context of mitochondrial dysfunction, inflammation, endothelial dysfunction, and tissue hypertrophy, and spotlight the role of IR in the development of VVs. We conclude that IR can contribute to the appearance of VVs.
AB - The prevalence of insulin resistance (IR) is growing every year, which determines the risks of developing type 2 diabetes and cardiovascular diseases. Currently, IR is not recognized as a risk factor for the development of varicose veins (VVs), but the connection between the two is tacitly obvious because obesity and diabetes are risk factors for VVs. In this review, we have attempted to highlight the common nature of these two conditions in the context of mitochondrial dysfunction, inflammation, endothelial dysfunction, and tissue hypertrophy, and spotlight the role of IR in the development of VVs. We conclude that IR can contribute to the appearance of VVs.
KW - Insulin resistance
KW - endothelial dysfunction
KW - inflammation
KW - mitochondrial dysfunction
KW - tissue hypertrophy
KW - varicose veins
UR - https://www.scopus.com/record/display.uri?eid=2-s2.0-85217230484&origin=inward&txGid=096c191592a7e32d86a886464b5da4b7
UR - https://www.elibrary.ru/item.asp?id=74723279
UR - https://www.mendeley.com/catalogue/a975d8d2-8386-3f7a-95e8-dd6210201068/
U2 - 10.20517/2574-1209.2024.26
DO - 10.20517/2574-1209.2024.26
M3 - Article
VL - 8
JO - Vessel Plus
JF - Vessel Plus
SN - 2574-1209
M1 - 36
ER -
ID: 64716019