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Usnic acid derivatives are effective inhibitors of tyrosyl-DNA phosphodiesterase 1. / Zakharenko, A. L.; Luzina, O. A.; Sokolov, D. N. и др.

в: Russian Journal of Bioorganic Chemistry, Том 43, № 1, 01.01.2017, стр. 84-90.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Zakharenko, AL, Luzina, OA, Sokolov, DN, Zakharova, OD, Rakhmanova, ME, Chepanova, AA, Dyrkheeva, NS, Lavrik, OI & Salakhutdinov, NF 2017, 'Usnic acid derivatives are effective inhibitors of tyrosyl-DNA phosphodiesterase 1', Russian Journal of Bioorganic Chemistry, Том. 43, № 1, стр. 84-90. https://doi.org/10.1134/S1068162017010125

APA

Zakharenko, A. L., Luzina, O. A., Sokolov, D. N., Zakharova, O. D., Rakhmanova, M. E., Chepanova, A. A., Dyrkheeva, N. S., Lavrik, O. I., & Salakhutdinov, N. F. (2017). Usnic acid derivatives are effective inhibitors of tyrosyl-DNA phosphodiesterase 1. Russian Journal of Bioorganic Chemistry, 43(1), 84-90. https://doi.org/10.1134/S1068162017010125

Vancouver

Zakharenko AL, Luzina OA, Sokolov DN, Zakharova OD, Rakhmanova ME, Chepanova AA и др. Usnic acid derivatives are effective inhibitors of tyrosyl-DNA phosphodiesterase 1. Russian Journal of Bioorganic Chemistry. 2017 янв. 1;43(1):84-90. doi: 10.1134/S1068162017010125

Author

Zakharenko, A. L. ; Luzina, O. A. ; Sokolov, D. N. и др. / Usnic acid derivatives are effective inhibitors of tyrosyl-DNA phosphodiesterase 1. в: Russian Journal of Bioorganic Chemistry. 2017 ; Том 43, № 1. стр. 84-90.

BibTeX

@article{79f37df88d904f1882927095e8126586,
title = "Usnic acid derivatives are effective inhibitors of tyrosyl-DNA phosphodiesterase 1",
abstract = "The synthesis of (+)-usnic acid derivatives is described. The derivatives contain one or two cyano groups, connected to the acetophenone fragment of dibenzofuran core by linkers of different length and character, or some other modifications. The influence of these compounds on the activity of recombinant human tyrosyl-DNA phosphodiesterase 1 and MCF-7 tumor cells{\textquoteright} viability has been estimated. The data indicate a distinct dependence of functional characteristics of the compounds on their structure.",
keywords = "tyrosyl-DNA phosphodiesterase 1, tyrosyl-DNA phosphodiesterase 1 inhibitors, usnic acid",
author = "Zakharenko, {A. L.} and Luzina, {O. A.} and Sokolov, {D. N.} and Zakharova, {O. D.} and Rakhmanova, {M. E.} and Chepanova, {A. A.} and Dyrkheeva, {N. S.} and Lavrik, {O. I.} and Salakhutdinov, {N. F.}",
year = "2017",
month = jan,
day = "1",
doi = "10.1134/S1068162017010125",
language = "English",
volume = "43",
pages = "84--90",
journal = "Russian Journal of Bioorganic Chemistry",
issn = "1068-1620",
publisher = "MAIK NAUKA/INTERPERIODICA/SPRINGER",
number = "1",

}

RIS

TY - JOUR

T1 - Usnic acid derivatives are effective inhibitors of tyrosyl-DNA phosphodiesterase 1

AU - Zakharenko, A. L.

AU - Luzina, O. A.

AU - Sokolov, D. N.

AU - Zakharova, O. D.

AU - Rakhmanova, M. E.

AU - Chepanova, A. A.

AU - Dyrkheeva, N. S.

AU - Lavrik, O. I.

AU - Salakhutdinov, N. F.

PY - 2017/1/1

Y1 - 2017/1/1

N2 - The synthesis of (+)-usnic acid derivatives is described. The derivatives contain one or two cyano groups, connected to the acetophenone fragment of dibenzofuran core by linkers of different length and character, or some other modifications. The influence of these compounds on the activity of recombinant human tyrosyl-DNA phosphodiesterase 1 and MCF-7 tumor cells’ viability has been estimated. The data indicate a distinct dependence of functional characteristics of the compounds on their structure.

AB - The synthesis of (+)-usnic acid derivatives is described. The derivatives contain one or two cyano groups, connected to the acetophenone fragment of dibenzofuran core by linkers of different length and character, or some other modifications. The influence of these compounds on the activity of recombinant human tyrosyl-DNA phosphodiesterase 1 and MCF-7 tumor cells’ viability has been estimated. The data indicate a distinct dependence of functional characteristics of the compounds on their structure.

KW - tyrosyl-DNA phosphodiesterase 1

KW - tyrosyl-DNA phosphodiesterase 1 inhibitors

KW - usnic acid

UR - http://www.scopus.com/inward/record.url?scp=85012864677&partnerID=8YFLogxK

U2 - 10.1134/S1068162017010125

DO - 10.1134/S1068162017010125

M3 - Article

AN - SCOPUS:85012864677

VL - 43

SP - 84

EP - 90

JO - Russian Journal of Bioorganic Chemistry

JF - Russian Journal of Bioorganic Chemistry

SN - 1068-1620

IS - 1

ER -

ID: 8681160