TY - JOUR

T1 - Using a Microchannel Reactor to Optimize the Production of 1-Alkyl-3-Methylimidazolium Chlorides

AU - Klimenko, A. S.

AU - Andreev, D. V.

AU - Prikhod’ko, S. A.

AU - Gribovskii, A. G.

AU - Makarshin, L. L.

AU - Adonin, N. Yu

PY - 2020/7/1

Y1 - 2020/7/1

N2 - The possibility of using microchannel flow reactors to obtain the kinetic and technological parameters of the synthesis of 1-butyl-3-methylimidazolium chloride (BMIMCl) ionic liquid is demonstrated for the reaction of 1-methylimidazole (MIm) with 1-chlorobutane with no solvents. BMIMCl is produced with high selectivity and specific output in a microchannel flow reactor at temperatures of 120–180°C a contact time of 2–45 min, and a pressure of 20 bar. A positive result is obtained, due to the laminar profile of the flow and a uniform distribution of the reagents concentration over the microchannel cross section. Studying the kinetics of the process in a microchannel flow reactor reveals a shift of the reaction to the mode of diffusive inhibition at temperatures above 150°C. The kinetic data obtained for BMIMCl synthesis are used to develop ways of producing 1-ethyl-3-methylimidazolium and 1-hexyl-3-methylimidazolium chlorides (EMIMCl and HMIMCl, respectively) under the conditions of a microchannel flow reactor. The approach proposed in this work is of interest in developing flow and periodic facilities for the low-tonnage production of dialkylimidazolium, ammonium, and pyridinium salts via quaternization of the corresponding alkyl chlorides and nitrogen-containing bases.

AB - The possibility of using microchannel flow reactors to obtain the kinetic and technological parameters of the synthesis of 1-butyl-3-methylimidazolium chloride (BMIMCl) ionic liquid is demonstrated for the reaction of 1-methylimidazole (MIm) with 1-chlorobutane with no solvents. BMIMCl is produced with high selectivity and specific output in a microchannel flow reactor at temperatures of 120–180°C a contact time of 2–45 min, and a pressure of 20 bar. A positive result is obtained, due to the laminar profile of the flow and a uniform distribution of the reagents concentration over the microchannel cross section. Studying the kinetics of the process in a microchannel flow reactor reveals a shift of the reaction to the mode of diffusive inhibition at temperatures above 150°C. The kinetic data obtained for BMIMCl synthesis are used to develop ways of producing 1-ethyl-3-methylimidazolium and 1-hexyl-3-methylimidazolium chlorides (EMIMCl and HMIMCl, respectively) under the conditions of a microchannel flow reactor. The approach proposed in this work is of interest in developing flow and periodic facilities for the low-tonnage production of dialkylimidazolium, ammonium, and pyridinium salts via quaternization of the corresponding alkyl chlorides and nitrogen-containing bases.

KW - 1-alkyl-3-methylimidazolium chloride

KW - BMIMCl

KW - ionic liquid

KW - microchannel flow reactor

KW - quaternization reaction

KW - DESIGN

KW - MICROREACTOR

KW - FLOW

KW - SOLVENT

KW - PHASE

KW - TEMPERATURE

KW - KINETICS

KW - CHEMISTRY

KW - IONIC LIQUIDS

UR - http://www.scopus.com/inward/record.url?scp=85091645802&partnerID=8YFLogxK

U2 - 10.1134/S2070050420030071

DO - 10.1134/S2070050420030071

M3 - Article

AN - SCOPUS:85091645802

VL - 12

SP - 207

EP - 215

JO - Catalysis in Industry

JF - Catalysis in Industry

SN - 2070-0504

IS - 3

ER -