Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Transfer of Asymmetry between Proteinogenic Amino Acids under Harsh Conditions. / Tarasevych, Arkadii V.; Vives, Thomas; Snytnikov, Valeriy N. и др.
в: Origins of Life and Evolution of Biospheres, Том 47, № 3, 01.09.2017, стр. 371-379.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Transfer of Asymmetry between Proteinogenic Amino Acids under Harsh Conditions
AU - Tarasevych, Arkadii V.
AU - Vives, Thomas
AU - Snytnikov, Valeriy N.
AU - Guillemin, Jean Claude
PY - 2017/9/1
Y1 - 2017/9/1
N2 - The heating above 400 °C of serine, cysteine, selenocysteine and threonine leads to a complete decomposition of the amino acids and to the formation in low yields of alanine for the three formers and of 2-aminobutyric acid for the latter. At higher temperature, this amino acid is observed only when sublimable α-alkyl-α-amino acids are present, and with an enantiomeric excess dependent on several parameters. Enantiopure or enantioenriched Ser, Cys, Sel or Thr is not able to transmit its enantiomeric excess to the amino acid formed during its decomposition. The presence during the sublimation-decomposition of enantioenriched valine or isoleucine leads to the enantioenrichment of all sublimable amino acids independently of the presence of many decomposition products coming from the unstable derivative. All these studies give information on a potentially prebiotic key-reaction of abiotic transformations between α-amino acids and their evolution to homochirality.
AB - The heating above 400 °C of serine, cysteine, selenocysteine and threonine leads to a complete decomposition of the amino acids and to the formation in low yields of alanine for the three formers and of 2-aminobutyric acid for the latter. At higher temperature, this amino acid is observed only when sublimable α-alkyl-α-amino acids are present, and with an enantiomeric excess dependent on several parameters. Enantiopure or enantioenriched Ser, Cys, Sel or Thr is not able to transmit its enantiomeric excess to the amino acid formed during its decomposition. The presence during the sublimation-decomposition of enantioenriched valine or isoleucine leads to the enantioenrichment of all sublimable amino acids independently of the presence of many decomposition products coming from the unstable derivative. All these studies give information on a potentially prebiotic key-reaction of abiotic transformations between α-amino acids and their evolution to homochirality.
KW - Amino acid
KW - Enantioenrichment
KW - Sublimation
KW - Transfer of asymmetry
KW - PHASE
KW - AMPLIFICATION
KW - PEPTIDES
KW - SERINE
KW - MECHANISM
KW - SUBLIMATION
KW - DECOMPOSITION
UR - http://www.scopus.com/inward/record.url?scp=85016502436&partnerID=8YFLogxK
U2 - 10.1007/s11084-017-9535-4
DO - 10.1007/s11084-017-9535-4
M3 - Article
C2 - 28361302
AN - SCOPUS:85016502436
VL - 47
SP - 371
EP - 379
JO - Origins of Life and Evolution of Biospheres
JF - Origins of Life and Evolution of Biospheres
SN - 0169-6149
IS - 3
ER -
ID: 9981069