Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
The story of the lost twins : decoding the genetic identities of the Kumhar and Kurcha populations from the Indian subcontinent. / Das, Ranajit; Ivanisenko, Vladimir A.; Anashkina, Anastasia A. и др.
в: BMC Genetics, Том 21, № Suppl 1, 117, 01.10.2020.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - The story of the lost twins
T2 - decoding the genetic identities of the Kumhar and Kurcha populations from the Indian subcontinent
AU - Das, Ranajit
AU - Ivanisenko, Vladimir A.
AU - Anashkina, Anastasia A.
AU - Upadhyai, Priyanka
N1 - Funding Information: The publication cost was covered by Russian Ministry of Education and Science, Project No. 28.12487.2018/12.1. “Investigation, analysis and complex independent expertise of projects of the National technological initiatives, including the accompanying of projects of «road map» «NeuroNet»”. The funding body had no role in design of the study, analysis, data interpretation and writing the manuscript. Acknowledgements About this supplement Publisher Copyright: © 2020, The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2020/10/1
Y1 - 2020/10/1
N2 - Background: The population structure of the Indian subcontinent is a tapestry of extraordinary diversity characterized by the amalgamation of autochthonous and immigrant ancestries and rigid enforcement of sociocultural stratification. Here we investigated the genetic origin and population history of the Kumhars, a group of people who inhabit large parts of northern India. We compared 27 previously published Kumhar SNP genotype data sampled from Uttar Pradesh in north India to various modern day and ancient populations. Results: Various approaches such as Principal Component Analysis (PCA), Admixture, TreeMix concurred that Kumhars have high ASI ancestry, minimal Steppe component and high genomic proximity to the Kurchas, a small and relatively little-known population found ~ 2500 km away in Kerala, south India. Given the same, biogeographical mapping using Geographic Population Structure (GPS) assigned most Kumhar samples in areas neighboring to those where Kurchas are found in south India. Conclusions: We hypothesize that the significant genomic similarity between two apparently distinct modern-day Indian populations that inhabit well separated geographical areas with no known overlapping history or links, likely alludes to their common origin during or post the decline of the Indus Valley Civilization (estimated by ALDER). Thereafter, while they dispersed towards opposite ends of the Indian subcontinent, their genomic integrity and likeness remained preserved due to endogamous social practices. Our findings illuminate the genomic history of two Indian populations, allowing a glimpse into one or few of numerous of human migrations that likely occurred across the Indian subcontinent and contributed to shape its varied and vibrant evolutionary past.
AB - Background: The population structure of the Indian subcontinent is a tapestry of extraordinary diversity characterized by the amalgamation of autochthonous and immigrant ancestries and rigid enforcement of sociocultural stratification. Here we investigated the genetic origin and population history of the Kumhars, a group of people who inhabit large parts of northern India. We compared 27 previously published Kumhar SNP genotype data sampled from Uttar Pradesh in north India to various modern day and ancient populations. Results: Various approaches such as Principal Component Analysis (PCA), Admixture, TreeMix concurred that Kumhars have high ASI ancestry, minimal Steppe component and high genomic proximity to the Kurchas, a small and relatively little-known population found ~ 2500 km away in Kerala, south India. Given the same, biogeographical mapping using Geographic Population Structure (GPS) assigned most Kumhar samples in areas neighboring to those where Kurchas are found in south India. Conclusions: We hypothesize that the significant genomic similarity between two apparently distinct modern-day Indian populations that inhabit well separated geographical areas with no known overlapping history or links, likely alludes to their common origin during or post the decline of the Indus Valley Civilization (estimated by ALDER). Thereafter, while they dispersed towards opposite ends of the Indian subcontinent, their genomic integrity and likeness remained preserved due to endogamous social practices. Our findings illuminate the genomic history of two Indian populations, allowing a glimpse into one or few of numerous of human migrations that likely occurred across the Indian subcontinent and contributed to shape its varied and vibrant evolutionary past.
KW - Indus Valley civilization
KW - Kumhar
KW - Kurchas
KW - South Asian population history
KW - COMPONENTS
KW - WIDE
KW - HUMAN COLONIZATION
KW - HISTORY
UR - http://www.scopus.com/inward/record.url?scp=85093874880&partnerID=8YFLogxK
U2 - 10.1186/s12863-020-00919-2
DO - 10.1186/s12863-020-00919-2
M3 - Article
C2 - 33092524
AN - SCOPUS:85093874880
VL - 21
JO - BMC Genetics
JF - BMC Genetics
SN - 1471-2156
IS - Suppl 1
M1 - 117
ER -
ID: 26000440