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The role of stump pressure and cerebral oximetry in predicting ischaemic brain damage during carotid endarterectomy. / Kuzhuget, Rossi; Starodubtsev, Vladimir; Ignatenko, Pavel и др.

в: Brain Injury, Том 31, № 13-14, 06.12.2017, стр. 1944-1950.

Результаты исследований: Научные публикации в периодических изданияхстатьяРецензирование

Harvard

Kuzhuget, R, Starodubtsev, V, Ignatenko, P, Starodubtseva, A, Voroshilina, O, Ruzankin, P & Karpenko, A 2017, 'The role of stump pressure and cerebral oximetry in predicting ischaemic brain damage during carotid endarterectomy', Brain Injury, Том. 31, № 13-14, стр. 1944-1950. https://doi.org/10.1080/02699052.2017.1347279

APA

Kuzhuget, R., Starodubtsev, V., Ignatenko, P., Starodubtseva, A., Voroshilina, O., Ruzankin, P., & Karpenko, A. (2017). The role of stump pressure and cerebral oximetry in predicting ischaemic brain damage during carotid endarterectomy. Brain Injury, 31(13-14), 1944-1950. https://doi.org/10.1080/02699052.2017.1347279

Vancouver

Kuzhuget R, Starodubtsev V, Ignatenko P, Starodubtseva A, Voroshilina O, Ruzankin P и др. The role of stump pressure and cerebral oximetry in predicting ischaemic brain damage during carotid endarterectomy. Brain Injury. 2017 дек. 6;31(13-14):1944-1950. doi: 10.1080/02699052.2017.1347279

Author

Kuzhuget, Rossi ; Starodubtsev, Vladimir ; Ignatenko, Pavel и др. / The role of stump pressure and cerebral oximetry in predicting ischaemic brain damage during carotid endarterectomy. в: Brain Injury. 2017 ; Том 31, № 13-14. стр. 1944-1950.

BibTeX

@article{eb3974b180bf4d0fb17cff45c56f8fe3,
title = "The role of stump pressure and cerebral oximetry in predicting ischaemic brain damage during carotid endarterectomy",
abstract = "Objective is to compare the predictive value of stump pressure (SP) and cerebral oximetry (rSO2) levels in the evaluation of ischaemic injury of the cerebrum during clamping of the carotid artery (CCA) without temporary shunt (TS). Methods We included 84 patients with an asymptomatic stenosis (>70%) of the internal carotid artery (ICA) who underwent carotid endarterectomy (CEA) under GA. Cerebral ischaemic tolerance (CIT) was determined on the basis of SP, rSO2 and ∆rSO2 (↓rSO2 from baseline) during CCA. The levels of S100 protein (S100) and neuron-specific enolase (NSE) were measured on each stage of the study. MRI was performed for all patients. Results There were no perioperative strokes and myocardial infarctions during the study. Temporary shutdown of blood flow in CAs during CEA is accompanied by a significant elevation of S100, NSE concentration with their subsequent restoration (three days after surgery). ROC analysis showed that none of the methods for CIT assessment (SP, rSO2 and ∆rSO2) was a valuable predictor of cerebral damage during CEA. Conclusion SP with a threshold value of ≤40 mmHg has an average quality of prediction (AUC = 63). ∆rSO2 of ≥20% and a threshold value of rSO2 ≤ 40% have an unsatisfactory quality of prediction (AUC < 60).",
keywords = "Carotid endarterectomy, cerebral circulation, cerebral damage markers, cerebral ischaemia, BIOMARKERS, STROKE, PROTEIN, NEURON-SPECIFIC ENOLASE, TRANSCRANIAL DOPPLER, GENERAL-ANESTHESIA",
author = "Rossi Kuzhuget and Vladimir Starodubtsev and Pavel Ignatenko and Alexandra Starodubtseva and Olga Voroshilina and Pavel Ruzankin and Andrey Karpenko",
year = "2017",
month = dec,
day = "6",
doi = "10.1080/02699052.2017.1347279",
language = "English",
volume = "31",
pages = "1944--1950",
journal = "Brain Injury",
issn = "0269-9052",
publisher = "Informa Healthcare",
number = "13-14",

}

RIS

TY - JOUR

T1 - The role of stump pressure and cerebral oximetry in predicting ischaemic brain damage during carotid endarterectomy

AU - Kuzhuget, Rossi

AU - Starodubtsev, Vladimir

AU - Ignatenko, Pavel

AU - Starodubtseva, Alexandra

AU - Voroshilina, Olga

AU - Ruzankin, Pavel

AU - Karpenko, Andrey

PY - 2017/12/6

Y1 - 2017/12/6

N2 - Objective is to compare the predictive value of stump pressure (SP) and cerebral oximetry (rSO2) levels in the evaluation of ischaemic injury of the cerebrum during clamping of the carotid artery (CCA) without temporary shunt (TS). Methods We included 84 patients with an asymptomatic stenosis (>70%) of the internal carotid artery (ICA) who underwent carotid endarterectomy (CEA) under GA. Cerebral ischaemic tolerance (CIT) was determined on the basis of SP, rSO2 and ∆rSO2 (↓rSO2 from baseline) during CCA. The levels of S100 protein (S100) and neuron-specific enolase (NSE) were measured on each stage of the study. MRI was performed for all patients. Results There were no perioperative strokes and myocardial infarctions during the study. Temporary shutdown of blood flow in CAs during CEA is accompanied by a significant elevation of S100, NSE concentration with their subsequent restoration (three days after surgery). ROC analysis showed that none of the methods for CIT assessment (SP, rSO2 and ∆rSO2) was a valuable predictor of cerebral damage during CEA. Conclusion SP with a threshold value of ≤40 mmHg has an average quality of prediction (AUC = 63). ∆rSO2 of ≥20% and a threshold value of rSO2 ≤ 40% have an unsatisfactory quality of prediction (AUC < 60).

AB - Objective is to compare the predictive value of stump pressure (SP) and cerebral oximetry (rSO2) levels in the evaluation of ischaemic injury of the cerebrum during clamping of the carotid artery (CCA) without temporary shunt (TS). Methods We included 84 patients with an asymptomatic stenosis (>70%) of the internal carotid artery (ICA) who underwent carotid endarterectomy (CEA) under GA. Cerebral ischaemic tolerance (CIT) was determined on the basis of SP, rSO2 and ∆rSO2 (↓rSO2 from baseline) during CCA. The levels of S100 protein (S100) and neuron-specific enolase (NSE) were measured on each stage of the study. MRI was performed for all patients. Results There were no perioperative strokes and myocardial infarctions during the study. Temporary shutdown of blood flow in CAs during CEA is accompanied by a significant elevation of S100, NSE concentration with their subsequent restoration (three days after surgery). ROC analysis showed that none of the methods for CIT assessment (SP, rSO2 and ∆rSO2) was a valuable predictor of cerebral damage during CEA. Conclusion SP with a threshold value of ≤40 mmHg has an average quality of prediction (AUC = 63). ∆rSO2 of ≥20% and a threshold value of rSO2 ≤ 40% have an unsatisfactory quality of prediction (AUC < 60).

KW - Carotid endarterectomy

KW - cerebral circulation

KW - cerebral damage markers

KW - cerebral ischaemia

KW - BIOMARKERS

KW - STROKE

KW - PROTEIN

KW - NEURON-SPECIFIC ENOLASE

KW - TRANSCRANIAL DOPPLER

KW - GENERAL-ANESTHESIA

UR - http://www.scopus.com/inward/record.url?scp=85029447197&partnerID=8YFLogxK

U2 - 10.1080/02699052.2017.1347279

DO - 10.1080/02699052.2017.1347279

M3 - Article

C2 - 28872355

AN - SCOPUS:85029447197

VL - 31

SP - 1944

EP - 1950

JO - Brain Injury

JF - Brain Injury

SN - 0269-9052

IS - 13-14

ER -

ID: 9429177