TY - JOUR

T1 - The relationship between gastroesophageal pathogenic reflux and metabolic syndrome

AU - Bulgakova, Elizaveta D.

AU - Shrayner, Evgenia V.

AU - Khavkin, Anatoly I.

AU - Lifshits, Galina I.

AU - Nikolaychuk, Kirill M.

AU - Denisov, Mikhail Yu

N1 - Взаимосвязь гастроэзофагеальной рефлюксной болезни и метаболического синдрома / Е. Д. Булгакова, Е. В. Шрайнер, А. И. Хавкин [и др.] // Экспериментальная и клиническая гастроэнтерология. – 2024. – № 2 (222). – С. 131-140.

PY - 2024

Y1 - 2024

N2 - Currently, special attention is drawn to the phenomenon of comorbidity of chronic non-infectious diseases. The emergence of comorbidity is facilitated by the high incidence of coexisting diseases. One such combination is GERD and metabolic syndrome (MS). GERD and MS are multifactorial diseases, the pathogenesis of which is intertwined and mutually aggravates each other. Every year throughout the world and the Russian Federation, there is a clear trend towards an increase in the incidence of pathology of the upper gastrointestinal tract, namely gastroesophageal reflux disease (GERD). The prevalence of obesity in Russia over 40 years of observation has increased 4 times among men and 1.5 times among women. Despite the high incidence, to date there is no diagnosis of “metabolic syndrome” (MS) in ICD-10. MS is coded based on its constituent pathologies (obesity, dyslipidemia, insulin resistance, arterial hypertension). Treatment of this comorbid pathology requires a multidisciplinary approach, thereby placing a high burden on the healthcare system. This article displays the features of the pathogenesis and clinical picture of GERD, as well as the combination of this pathology with the components of MS.

AB - Currently, special attention is drawn to the phenomenon of comorbidity of chronic non-infectious diseases. The emergence of comorbidity is facilitated by the high incidence of coexisting diseases. One such combination is GERD and metabolic syndrome (MS). GERD and MS are multifactorial diseases, the pathogenesis of which is intertwined and mutually aggravates each other. Every year throughout the world and the Russian Federation, there is a clear trend towards an increase in the incidence of pathology of the upper gastrointestinal tract, namely gastroesophageal reflux disease (GERD). The prevalence of obesity in Russia over 40 years of observation has increased 4 times among men and 1.5 times among women. Despite the high incidence, to date there is no diagnosis of “metabolic syndrome” (MS) in ICD-10. MS is coded based on its constituent pathologies (obesity, dyslipidemia, insulin resistance, arterial hypertension). Treatment of this comorbid pathology requires a multidisciplinary approach, thereby placing a high burden on the healthcare system. This article displays the features of the pathogenesis and clinical picture of GERD, as well as the combination of this pathology with the components of MS.

KW - Barrett’s esophagus

KW - arterial hypertension

KW - dyslipidemia

KW - esophageal adenocarcinoma

KW - gastroesophageal reflux disease

KW - insulin resistance

KW - metabolic syndrome

KW - obesity

UR - https://www.scopus.com/record/display.uri?eid=2-s2.0-85189441091&origin=inward&txGid=cc24d5db8b290c772d2a6ea576e6eea3

UR - https://www.mendeley.com/catalogue/85fc539a-8965-3a36-b272-552b54610274/

U2 - 10.31146/1682-8658-ecg-222-2-131-140

DO - 10.31146/1682-8658-ecg-222-2-131-140

M3 - Article

SP - 131

EP - 140

JO - Экспериментальная и клиническая гастроэнтерология

JF - Экспериментальная и клиническая гастроэнтерология

SN - 1682-8658

IS - 2

ER -