Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Synthesis and biological activity of heterocyclic borneol derivatives. / Sokolova, Anastasiya S.; Yarovaya, Оlga I.; Shtro, Anna A. и др.
в: Chemistry of Heterocyclic Compounds, Том 53, № 3, 01.03.2017, стр. 371-377.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Synthesis and biological activity of heterocyclic borneol derivatives
AU - Sokolova, Anastasiya S.
AU - Yarovaya, Оlga I.
AU - Shtro, Anna A.
AU - Borisova, Marina S.
AU - Morozova, Ekaterina A.
AU - Tolstikova, Tatyana G.
AU - Zarubaev, Vladimir V.
AU - Salakhutdinov, Nariman F.
N1 - Publisher Copyright: © 2017 Springer Science+Business Media New York.
PY - 2017/3/1
Y1 - 2017/3/1
N2 - A series of novel heterocyclic derivatives of (-)-borneol has been prepared by the interaction of (1S,2R,4S)-1,7,7-trimethylbicyclo[2.2.1]-heptan-2-yl 2-chloroacetate and (1S,2R,4S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl 3-chloropropanoate with different N- and S-nucleophiles. The obtained products were screened for antiviral, antiulcer, and analgesic activity.
AB - A series of novel heterocyclic derivatives of (-)-borneol has been prepared by the interaction of (1S,2R,4S)-1,7,7-trimethylbicyclo[2.2.1]-heptan-2-yl 2-chloroacetate and (1S,2R,4S)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl 3-chloropropanoate with different N- and S-nucleophiles. The obtained products were screened for antiviral, antiulcer, and analgesic activity.
KW - (–)-borneol
KW - 1H-benzimidazole-2-thiol
KW - Analgesic activity
KW - Antiulcer activity
KW - Antiviral activity
KW - Benzoxazole-2-thiol
KW - Benzthiazole-2-thiol
KW - antiulcer activity
KW - ACID
KW - ASSAY
KW - (-)-borneol
KW - TOXICITY
KW - antiviral activity
KW - DISCOVERY
KW - benzthiazole-2-thiol
KW - analgesic activity
KW - INHIBITORS
KW - benzoxazole-2-thiol
UR - http://www.scopus.com/inward/record.url?scp=85018809423&partnerID=8YFLogxK
U2 - 10.1007/s10593-017-2063-3
DO - 10.1007/s10593-017-2063-3
M3 - Article
AN - SCOPUS:85018809423
VL - 53
SP - 371
EP - 377
JO - Chemistry of Heterocyclic Compounds
JF - Chemistry of Heterocyclic Compounds
SN - 0009-3122
IS - 3
ER -
ID: 9560829