TY - CONF

T1 - Survival of Cancer Cells Under Different Cold Plasma Jet Initiation Methods

AU - Milakhina, Elena

AU - Gugin, Pavel

AU - Shevchenko, Gleb

AU - Zakrevsky, Dmitry

AU - Koval, Olga

AU - Biryukov, Mikhail

AU - Polyakova, Alina

N1 - E. Milakhina et al., "Survival of Cancer Cells Under Different Cold Plasma Jet Initiation Methods," 2025 IEEE XVII International Scientific and Technical Conference on Actual Problems of Electronic Instrument Engineering (APEIE), Novosibirsk, Russian Federation, 2025, pp. 1-4, doi: 10.1109/APEIE66761.2025.11289263. This research was performed financially supported by State Assignment № FWGW-2025-0019.

PY - 2025/11/14

Y1 - 2025/11/14

N2 - In this work the optimal operating modes of the atmospheric pressure cold plasma jet generation source were determined for applications involving biological objects, ensuring maximum suppression of cancer cell viability. A comparative study was conducted on the survival of cancer cells after treatment with a cold plasma helium jet under various voltage supply modes, the frequency of current contact with the surface of a biological object, and the different duration of voltage initiation pulses. The conditions ensuring the maximum reduction in the viability of cancer cells have been determined. In the course of the work, it was established that cold plasma treatment of cancer cells with a plasma jet, initiated by different modes, but providing the same intensity levels of OH radical release in the contact zone, leads to the same levels of decreased viability. The obtained results are important for the development of standardized plasma therapy protocols in oncology and other areas of medicine.

AB - In this work the optimal operating modes of the atmospheric pressure cold plasma jet generation source were determined for applications involving biological objects, ensuring maximum suppression of cancer cell viability. A comparative study was conducted on the survival of cancer cells after treatment with a cold plasma helium jet under various voltage supply modes, the frequency of current contact with the surface of a biological object, and the different duration of voltage initiation pulses. The conditions ensuring the maximum reduction in the viability of cancer cells have been determined. In the course of the work, it was established that cold plasma treatment of cancer cells with a plasma jet, initiated by different modes, but providing the same intensity levels of OH radical release in the contact zone, leads to the same levels of decreased viability. The obtained results are important for the development of standardized plasma therapy protocols in oncology and other areas of medicine.

KW - струя холодной атмосферной плазмы

KW - низкотемпературная плазменная струя

KW - газовый разряд

KW - активные радикалы

KW - биомедицинские приложения

KW - плазменная медицина

KW - онкология

KW - электрофизические параметры

KW - спектральный анализ

KW - cold atmospheric plasma jet

KW - low-temperature plasma jet

KW - gas discharge

KW - active radicals

KW - biomedical applications

KW - plasma medicine

KW - oncology

KW - electrophysical parameters

KW - Spectral analysis

UR - https://www.scopus.com/pages/publications/105031766565

U2 - 10.1109/APEIE66761.2025.11289263

DO - 10.1109/APEIE66761.2025.11289263

M3 - Paper

SP - 1

EP - 4

T2 - 2025 IEEE XVII International Scientific and Technical Conference on Actual Problems of Electronic Instrument Engineering (APEIE)

Y2 - 14 November 2025 through 16 November 2025

ER -