TY - JOUR

T1 - Reproductive potential of the male (RPM)

T2 - the computer database of phenotypic and molecular genetic data for Russian men with impaired and normal fertility

AU - Bogomolov, Anton

AU - Osadchuk, Alexander

AU - Osadchuk, Ludmila

PY - 2020/12

Y1 - 2020/12

N2 - Currently, a trend of decline in male fertility is observed all over the world. The study of this trend has not only of scientific, but also of socio-economic importance. Many countries conduct studies of male reproductive potential and search environmental and genetic causes of the mentioned phenomenon. Previously published studies have not included data on the Russian male population. This work presents novel database "Reproductive Potential of the Male population of Russia" (RPM), which is almost the only source of such information about Russia. RPM was created using relational database management system MariaDB and is available at www.sysbio.ru/rpm. The database includes reproductive information of 1390 male volunteers from five large cities of Russia: Arkhangelsk, Novosibirsk, Kemerovo, Ulan-Ude and Yakutsk. The important feature of the developed database is the unique data of amultifactorial measurement of male fertility: spermatogenic, hormonal, metabolic and anthropological indices. The scientists can use published information in their studies of male reproductive potential as data of some Russian regions and compare it with data from other countries. Also the published data can be used to identify markers of infertility and subfertility, as well as to study ethnic and regional trends in fertility variability and demographic risks in Russia.

AB - Currently, a trend of decline in male fertility is observed all over the world. The study of this trend has not only of scientific, but also of socio-economic importance. Many countries conduct studies of male reproductive potential and search environmental and genetic causes of the mentioned phenomenon. Previously published studies have not included data on the Russian male population. This work presents novel database "Reproductive Potential of the Male population of Russia" (RPM), which is almost the only source of such information about Russia. RPM was created using relational database management system MariaDB and is available at www.sysbio.ru/rpm. The database includes reproductive information of 1390 male volunteers from five large cities of Russia: Arkhangelsk, Novosibirsk, Kemerovo, Ulan-Ude and Yakutsk. The important feature of the developed database is the unique data of amultifactorial measurement of male fertility: spermatogenic, hormonal, metabolic and anthropological indices. The scientists can use published information in their studies of male reproductive potential as data of some Russian regions and compare it with data from other countries. Also the published data can be used to identify markers of infertility and subfertility, as well as to study ethnic and regional trends in fertility variability and demographic risks in Russia.

KW - database

KW - male fertility

KW - phenotypic and molecular-genetic markers

KW - spermatogenesis

KW - SEMEN QUALITY

KW - GENERAL-POPULATION

KW - PARAMETERS

KW - CAG

U2 - 10.1515/jib-2020-0032

DO - 10.1515/jib-2020-0032

M3 - Article

VL - 17

JO - Journal of integrative bioinformatics

JF - Journal of integrative bioinformatics

SN - 1613-4516

IS - 4

M1 - 20200032

ER -