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Representation analysis of miRNA from clarified urine and urine microvesicles in prostate malignancies and non-malignant neoplasms. / Zaporozhchenko, I. A.; Bryzgunova, O. E.; Lekchnov, E. A. и др.

в: Biomeditsinskaya Khimiya, Том 64, № 1, 01.01.2018, стр. 38-45.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Zaporozhchenko, IA, Bryzgunova, OE, Lekchnov, EA, Osipov, ID, Zaripov, MM, Yurchenko, YB, Yarmoschuk, SV, Pashkovskaya, OA, Rykova, EY, Zheravin, AA & Laktionov, PP 2018, 'Representation analysis of miRNA from clarified urine and urine microvesicles in prostate malignancies and non-malignant neoplasms', Biomeditsinskaya Khimiya, Том. 64, № 1, стр. 38-45. https://doi.org/10.18097/PBMC20186401038

APA

Zaporozhchenko, I. A., Bryzgunova, O. E., Lekchnov, E. A., Osipov, I. D., Zaripov, M. M., Yurchenko, Y. B., Yarmoschuk, S. V., Pashkovskaya, O. A., Rykova, E. Y., Zheravin, A. A., & Laktionov, P. P. (2018). Representation analysis of miRNA from clarified urine and urine microvesicles in prostate malignancies and non-malignant neoplasms. Biomeditsinskaya Khimiya, 64(1), 38-45. https://doi.org/10.18097/PBMC20186401038

Vancouver

Zaporozhchenko IA, Bryzgunova OE, Lekchnov EA, Osipov ID, Zaripov MM, Yurchenko YB и др. Representation analysis of miRNA from clarified urine and urine microvesicles in prostate malignancies and non-malignant neoplasms. Biomeditsinskaya Khimiya. 2018 янв. 1;64(1):38-45. doi: 10.18097/PBMC20186401038

Author

Zaporozhchenko, I. A. ; Bryzgunova, O. E. ; Lekchnov, E. A. и др. / Representation analysis of miRNA from clarified urine and urine microvesicles in prostate malignancies and non-malignant neoplasms. в: Biomeditsinskaya Khimiya. 2018 ; Том 64, № 1. стр. 38-45.

BibTeX

@article{ffd5651b4d9b4c3191f7b124e7b71768,
title = "Representation analysis of miRNA from clarified urine and urine microvesicles in prostate malignancies and non-malignant neoplasms",
abstract = "Urine of prostate cancer patients contains tumor-specific biopolymers, including protein- and microvesicles associated miRNAs that can potentially be used as oncomarkers. Previously we have characterized urine extracellular vesicles and demonstrated diagnostic potential of their miRNA cargo. In this study, we have performed a comparative analysis of the expression of 84 miRNA in paired samples of urine microvesicles and clarified urine from healthy men, patients with benign hyperplasia and cancer of the prostate using miRCURY LNA miRNA qPCR Panels. Subsets of miRNAs with differences in expression between the fractions of the urine were found in all three groups. Two groups of miRNA were identified based on the patterns of their differential expression. They regulate several key signaling pathways associated with prostate cancer development.",
keywords = "Exosomes, Microvesicles, MiRNA, Prostate cancer, Urine, Body Fluids, Cell-Derived Microparticles, Extracellular Vesicles, Humans, Male, MicroRNAs, Prostatic Neoplasms",
author = "Zaporozhchenko, {I. A.} and Bryzgunova, {O. E.} and Lekchnov, {E. A.} and Osipov, {I. D.} and Zaripov, {M. M.} and Yurchenko, {Yu B.} and Yarmoschuk, {S. V.} and Pashkovskaya, {O. A.} and Rykova, {E. Yu} and Zheravin, {A. A.} and Laktionov, {P. P.}",
year = "2018",
month = jan,
day = "1",
doi = "10.18097/PBMC20186401038",
language = "English",
volume = "64",
pages = "38--45",
journal = "Biomeditsinskaya Khimiya",
issn = "2310-6905",
publisher = "Rossiiskaya Akademiya Meditsinskikh Nauk",
number = "1",

}

RIS

TY - JOUR

T1 - Representation analysis of miRNA from clarified urine and urine microvesicles in prostate malignancies and non-malignant neoplasms

AU - Zaporozhchenko, I. A.

AU - Bryzgunova, O. E.

AU - Lekchnov, E. A.

AU - Osipov, I. D.

AU - Zaripov, M. M.

AU - Yurchenko, Yu B.

AU - Yarmoschuk, S. V.

AU - Pashkovskaya, O. A.

AU - Rykova, E. Yu

AU - Zheravin, A. A.

AU - Laktionov, P. P.

PY - 2018/1/1

Y1 - 2018/1/1

N2 - Urine of prostate cancer patients contains tumor-specific biopolymers, including protein- and microvesicles associated miRNAs that can potentially be used as oncomarkers. Previously we have characterized urine extracellular vesicles and demonstrated diagnostic potential of their miRNA cargo. In this study, we have performed a comparative analysis of the expression of 84 miRNA in paired samples of urine microvesicles and clarified urine from healthy men, patients with benign hyperplasia and cancer of the prostate using miRCURY LNA miRNA qPCR Panels. Subsets of miRNAs with differences in expression between the fractions of the urine were found in all three groups. Two groups of miRNA were identified based on the patterns of their differential expression. They regulate several key signaling pathways associated with prostate cancer development.

AB - Urine of prostate cancer patients contains tumor-specific biopolymers, including protein- and microvesicles associated miRNAs that can potentially be used as oncomarkers. Previously we have characterized urine extracellular vesicles and demonstrated diagnostic potential of their miRNA cargo. In this study, we have performed a comparative analysis of the expression of 84 miRNA in paired samples of urine microvesicles and clarified urine from healthy men, patients with benign hyperplasia and cancer of the prostate using miRCURY LNA miRNA qPCR Panels. Subsets of miRNAs with differences in expression between the fractions of the urine were found in all three groups. Two groups of miRNA were identified based on the patterns of their differential expression. They regulate several key signaling pathways associated with prostate cancer development.

KW - Exosomes

KW - Microvesicles

KW - MiRNA

KW - Prostate cancer

KW - Urine

KW - Body Fluids

KW - Cell-Derived Microparticles

KW - Extracellular Vesicles

KW - Humans

KW - Male

KW - MicroRNAs

KW - Prostatic Neoplasms

UR - http://www.scopus.com/inward/record.url?scp=85043484547&partnerID=8YFLogxK

U2 - 10.18097/PBMC20186401038

DO - 10.18097/PBMC20186401038

M3 - Article

C2 - 29460833

AN - SCOPUS:85043484547

VL - 64

SP - 38

EP - 45

JO - Biomeditsinskaya Khimiya

JF - Biomeditsinskaya Khimiya

SN - 2310-6905

IS - 1

ER -

ID: 12101261