TY - JOUR

T1 - Recent advances in catalytic asymmetric dihydroxylation of olefins

AU - Ottenbacher, Roman V.

AU - Talsi, Evgenii P.

AU - Bryliakov, Konstantin P.

PY - 2019/6/5

Y1 - 2019/6/5

N2 - Asymmetric dihydroxylation of olefinic groups is an extremely important synthetic transformation which has been widely utilized to obtain optically pure pharmaceuticals and other fine chemical products. In recent years, catalyst systems for the asymmetric C=C dihydroxylations have attracted significant interest, the major research efforts being focused on designing environmentally benign catalyst systems. This mini-review summarizes recent progress in the field, surveying both novel, less toxic modifications of the classical osmium-based catalysts, and the highly efficient and enantioselective non-osmium catalyst systems. The bibliography includes 50 references.

AB - Asymmetric dihydroxylation of olefinic groups is an extremely important synthetic transformation which has been widely utilized to obtain optically pure pharmaceuticals and other fine chemical products. In recent years, catalyst systems for the asymmetric C=C dihydroxylations have attracted significant interest, the major research efforts being focused on designing environmentally benign catalyst systems. This mini-review summarizes recent progress in the field, surveying both novel, less toxic modifications of the classical osmium-based catalysts, and the highly efficient and enantioselective non-osmium catalyst systems. The bibliography includes 50 references.

KW - ENANTIOSELECTIVE CIS-DIHYDROXYLATION

KW - TRANS-DIHYDROXYLATION

KW - HYDROGEN-PEROXIDE

KW - NONHEME IRON

KW - ALKENES

KW - DIBORATION

KW - EPOXIDATION

KW - HYDROLYSIS

KW - OXIDATION

KW - CHEMO

UR - http://www.scopus.com/inward/record.url?scp=85076591702&partnerID=8YFLogxK

U2 - 10.1070/RCR4904

DO - 10.1070/RCR4904

M3 - Article

AN - SCOPUS:85076591702

VL - 88

SP - 1094

EP - 1103

JO - Russian Chemical Reviews

JF - Russian Chemical Reviews

SN - 0036-021X

IS - 11

ER -