TY - JOUR

T1 - Real time fuctional magnetic resonance imaging biofeedback

T2 - A new generation of neurotherapy

AU - Mel'nikov, M. Ye

AU - Shtark, M. B.

AU - Savelov, A. A.

AU - Bruhl, A.

PY - 2017/1/1

Y1 - 2017/1/1

N2 - The review summarizes the data related to the potential of the real time fMRI biofeedback (the rt-fMRI), a novel technology implementing instructing patients to modify the neural activity in the certain brain regions related to the disordered function. The recent positive results were gained for a treatment of the post-stroke impairments, the Parkinson disease, the pain syndrome, the tinnitus, the alcohol and nicotine abuse, the major depression, and phobias of contamination and spiders. The intervention was found to be less promising for schizophrenia and nearly ineffective for the criminal antisocial personality disorder. The reliability of the results is mostly poor due to subopti- mal study designs, lack of the control groups, and insufficient sample sizes. The article deals with biological basis of the technology, its current applications and perspectives, and also its methodological and methodical problems.

AB - The review summarizes the data related to the potential of the real time fMRI biofeedback (the rt-fMRI), a novel technology implementing instructing patients to modify the neural activity in the certain brain regions related to the disordered function. The recent positive results were gained for a treatment of the post-stroke impairments, the Parkinson disease, the pain syndrome, the tinnitus, the alcohol and nicotine abuse, the major depression, and phobias of contamination and spiders. The intervention was found to be less promising for schizophrenia and nearly ineffective for the criminal antisocial personality disorder. The reliability of the results is mostly poor due to subopti- mal study designs, lack of the control groups, and insufficient sample sizes. The article deals with biological basis of the technology, its current applications and perspectives, and also its methodological and methodical problems.

KW - BOLD response

KW - FMRI

KW - FMRI informed biofeedback

KW - Functional connectivity

KW - Machine learning

KW - Mental disorders

KW - Neu-rotherapy

KW - Neurovascular coupling

KW - Real time FMRI

KW - Region of interest

UR - http://www.scopus.com/inward/record.url?scp=85020658277&partnerID=8YFLogxK

M3 - Review article

AN - SCOPUS:85020658277

VL - 67

SP - 3

EP - 32

JO - Zhurnal Vysshei Nervnoi Deyatelnosti Imeni I.P. Pavlova

JF - Zhurnal Vysshei Nervnoi Deyatelnosti Imeni I.P. Pavlova

SN - 0044-4677

IS - 1

ER -