Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Raoultella bacteriophage RP180, a new member of the genus Kagunavirus, subfamily Guernseyvirinae. / Fofanov, Mikhail V.; Morozova, Vera V.; Kozlova, Yuliya N. и др.
в: Archives of Virology, Том 164, № 10, 01.10.2019, стр. 2637-2640.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Raoultella bacteriophage RP180, a new member of the genus Kagunavirus, subfamily Guernseyvirinae
AU - Fofanov, Mikhail V.
AU - Morozova, Vera V.
AU - Kozlova, Yuliya N.
AU - Tikunov, Artem Yu
AU - Babkin, Igor V.
AU - Poletaeva, Yuliya E.
AU - Ryabchikova, Elena I.
AU - Tikunova, Nina V.
N1 - Publisher Copyright: © 2019, Springer-Verlag GmbH Austria, part of Springer Nature. Copyright: Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2019/10/1
Y1 - 2019/10/1
N2 - A novel lytic Raoultella phage, RP180, was isolated and characterized. The RP180 genome has 44,851 base pairs and contains 65 putative genes, 35 of them encoding proteins whose functions were predicted based on sequence similarity to known proteins. The RP180 genome possesses a gene synteny typical of members of the subfamily Guernseyvirinae. Phylogenetic analysis of the RP180 genome and similar phage genomes revealed that phage RP180 is the first member of the genus Kagunavirus, subfamily Guernseyvirinae, that is specific for Raoultella sp. The genome of RP180 encodes a putative protein with similarity to CRISPR-like Cas4 nucleases, which belong to the pfam12705/PDDEXK_1 family. Cas4-like proteins of this family have been shown to interfere with the bacterial host type II-C CRISPR-Cas system.
AB - A novel lytic Raoultella phage, RP180, was isolated and characterized. The RP180 genome has 44,851 base pairs and contains 65 putative genes, 35 of them encoding proteins whose functions were predicted based on sequence similarity to known proteins. The RP180 genome possesses a gene synteny typical of members of the subfamily Guernseyvirinae. Phylogenetic analysis of the RP180 genome and similar phage genomes revealed that phage RP180 is the first member of the genus Kagunavirus, subfamily Guernseyvirinae, that is specific for Raoultella sp. The genome of RP180 encodes a putative protein with similarity to CRISPR-like Cas4 nucleases, which belong to the pfam12705/PDDEXK_1 family. Cas4-like proteins of this family have been shown to interfere with the bacterial host type II-C CRISPR-Cas system.
UR - http://www.scopus.com/inward/record.url?scp=85071899729&partnerID=8YFLogxK
U2 - 10.1007/s00705-019-04349-z
DO - 10.1007/s00705-019-04349-z
M3 - Article
C2 - 31372754
AN - SCOPUS:85071899729
VL - 164
SP - 2637
EP - 2640
JO - Archives of Virology
JF - Archives of Virology
SN - 0304-8608
IS - 10
ER -
ID: 21451624