TY - JOUR

T1 - Quantitative Metabolomic Dataset of Avian Eye Lenses

AU - Zelentsova, Ekaterina A.

AU - Mariasina, Sofia S.

AU - Yanshole, Vadim V.

AU - Yanshole, Lyudmila V.

AU - Osik, Nataliya A.

AU - Sharshov, Kirill A.

AU - Tsentalovich, Yuri P.

N1 - This research was funded by the Russian Science Foundation, grant number 21-74-00068. Публикация для корректировки.

PY - 2023/8

Y1 - 2023/8

N2 - Metabolomics is a powerful set of methods that uses analytical techniques to identify and quantify metabolites in biological samples, providing a snapshot of the metabolic state of a biological system. In medicine, metabolomics may help to reveal the molecular basis of a disease, make a diagnosis, and monitor treatment responses, while in agriculture, it can improve crop yields and plant breeding. However, animal metabolomics faces several challenges due to the complexity and diversity of animal metabolomes, the lack of standardized protocols, and the difficulty in interpreting metabolomic data. The current dataset includes quantitative metabolomic profiles of eye lenses from 26 bird species (111 specimens) that can aid researchers in developing new experiments, mathematical models, and integrating with other “-omics” data. The dataset includes raw 1H NMR spectra, protocols for sample preparation, and data preprocessing, with the final table containing information on the abundance of 89 reliably identified and quantified metabolites. The dataset is quantitative, making it relevant for supplementing with new specimens or comparison groups, followed by data mining and expected new interpretations. The data were obtained using the bird specimens collected in compliance with ethical standards and revealed potential differences in metabolic pathways due to phylogenetic differences or environmental exposure. Dataset: The dataset, including NMR raw data, metabolite concentrations, and experimental protocols, has been deposited in the MetaboLights repository, study identifier MTBLS7739 (https://www.ebi.ac.uk/metabolights/MTBLS7739 (accessed on 30 June 2023)). DOI: 10.1093/nar/gkz1019, PMID: 31691833. This dataset is now also available through the laboratory’s own database, accessible via the following links: amdb.online/amdb/experiments/145/; amdb.online/amdb/experiments/199/; amdb.online/amdb/experiments/255/; amdb.online/amdb/experiments/248/. Dataset License: CC0.

AB - Metabolomics is a powerful set of methods that uses analytical techniques to identify and quantify metabolites in biological samples, providing a snapshot of the metabolic state of a biological system. In medicine, metabolomics may help to reveal the molecular basis of a disease, make a diagnosis, and monitor treatment responses, while in agriculture, it can improve crop yields and plant breeding. However, animal metabolomics faces several challenges due to the complexity and diversity of animal metabolomes, the lack of standardized protocols, and the difficulty in interpreting metabolomic data. The current dataset includes quantitative metabolomic profiles of eye lenses from 26 bird species (111 specimens) that can aid researchers in developing new experiments, mathematical models, and integrating with other “-omics” data. The dataset includes raw 1H NMR spectra, protocols for sample preparation, and data preprocessing, with the final table containing information on the abundance of 89 reliably identified and quantified metabolites. The dataset is quantitative, making it relevant for supplementing with new specimens or comparison groups, followed by data mining and expected new interpretations. The data were obtained using the bird specimens collected in compliance with ethical standards and revealed potential differences in metabolic pathways due to phylogenetic differences or environmental exposure. Dataset: The dataset, including NMR raw data, metabolite concentrations, and experimental protocols, has been deposited in the MetaboLights repository, study identifier MTBLS7739 (https://www.ebi.ac.uk/metabolights/MTBLS7739 (accessed on 30 June 2023)). DOI: 10.1093/nar/gkz1019, PMID: 31691833. This dataset is now also available through the laboratory’s own database, accessible via the following links: amdb.online/amdb/experiments/145/; amdb.online/amdb/experiments/199/; amdb.online/amdb/experiments/255/; amdb.online/amdb/experiments/248/. Dataset License: CC0.

KW - NMR spectroscopy

KW - birds

KW - eye lens

KW - quantitative metabolomics

UR - https://www.scopus.com/record/display.uri?eid=2-s2.0-85168881437&origin=inward&txGid=7b8842fb3a5ee5015ec061ab18d933d1

UR - https://www.mendeley.com/catalogue/55badf19-91c9-391b-8baa-5dd38f920b33/

U2 - 10.3390/data8080125

DO - 10.3390/data8080125

M3 - Article

VL - 8

JO - Data

JF - Data

SN - 2306-5729

IS - 8

M1 - 125

ER -