Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Primary and secondary photochemical transformations of biologically active precursor - Nitro-Nitrosyl ruthenium complex. / Mikhailov, A. A.; Vorobyev, V. A.; Nadolinny, V. A. и др.
в: Journal of Photochemistry and Photobiology A: Chemistry, Том 373, 15.03.2019, стр. 37-44.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Primary and secondary photochemical transformations of biologically active precursor - Nitro-Nitrosyl ruthenium complex
AU - Mikhailov, A. A.
AU - Vorobyev, V. A.
AU - Nadolinny, V. A.
AU - Patrushev, Y. V.
AU - Yudina, Y. S.
AU - Kostin, G. A.
N1 - Funding Information: This work was supported by the Comprehensive Program of Fundamental Research SB RAS . Project No. II.1.16.1. Also we thank Federal Agency for Scientific Organizations for funding. Publisher Copyright: © 2019 Elsevier B.V.
PY - 2019/3/15
Y1 - 2019/3/15
N2 - Photolysis of [Ru(II)NOPy2(NO2)2OH] (A) complex was studied under blue light (445 nm) irradiation. The primary photo-process results in the formation of nitric oxide (NO) and a paramagnetic RuIII compound, the latter was detected by EPR technique. The quantum yield (6–11%) of primary photolytic process was determined from the evolution of UV–vis spectra in different solvents (water, ethanol, dimethyl sulfoxide and acetonitrile). The secondary processes compete with the NO-release and lead to a variety of ruthenium forms including new nitrosyl forms. Namely, processes of hydroxyl protonation, pyridine photocleavage and nitro – nitrito bond isomerization take a place. HPLC combined with IR and 15N – NMR spectroscopies clarified the composition of the new forms and their transformations during the photolysis. Supporting EPR and IR DFT calculations confirmed the structure of photoproducts. The oxidation of NO in the secondary processes significantly influences on the total amount of nitric oxide release and reaction routes.
AB - Photolysis of [Ru(II)NOPy2(NO2)2OH] (A) complex was studied under blue light (445 nm) irradiation. The primary photo-process results in the formation of nitric oxide (NO) and a paramagnetic RuIII compound, the latter was detected by EPR technique. The quantum yield (6–11%) of primary photolytic process was determined from the evolution of UV–vis spectra in different solvents (water, ethanol, dimethyl sulfoxide and acetonitrile). The secondary processes compete with the NO-release and lead to a variety of ruthenium forms including new nitrosyl forms. Namely, processes of hydroxyl protonation, pyridine photocleavage and nitro – nitrito bond isomerization take a place. HPLC combined with IR and 15N – NMR spectroscopies clarified the composition of the new forms and their transformations during the photolysis. Supporting EPR and IR DFT calculations confirmed the structure of photoproducts. The oxidation of NO in the secondary processes significantly influences on the total amount of nitric oxide release and reaction routes.
KW - Nitric oxide release
KW - Nitrosyl ruthenium
KW - Photochemistry
KW - Photocleavage
KW - NO
KW - OXIDE
KW - ACID
KW - APPROXIMATION
KW - CRYSTAL-STRUCTURE
KW - REACTIVITY
KW - IR
KW - LIGHT IRRADIATION
KW - NITROSYLRUTHENIUM
KW - LIGANDS
UR - http://www.scopus.com/inward/record.url?scp=85059485886&partnerID=8YFLogxK
U2 - 10.1016/j.jphotochem.2018.12.037
DO - 10.1016/j.jphotochem.2018.12.037
M3 - Article
AN - SCOPUS:85059485886
VL - 373
SP - 37
EP - 44
JO - Journal of Photochemistry and Photobiology A: Chemistry
JF - Journal of Photochemistry and Photobiology A: Chemistry
SN - 1010-6030
ER -
ID: 18068709