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Polymorphism of serotonin transporter gene in male subjects with antisocial behavior and MMA fighters. / Cherepkova, Elena V.; Maksimov, Vladimir V.; Aftanas, Lyubomir I.

в: Translational Psychiatry, Том 8, № 1, 248, 01.12.2018, стр. 248.

Результаты исследований: Научные публикации в периодических изданияхстатьяРецензирование

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Vancouver

Cherepkova EV, Maksimov VV, Aftanas LI. Polymorphism of serotonin transporter gene in male subjects with antisocial behavior and MMA fighters. Translational Psychiatry. 2018 дек. 1;8(1):248. 248. doi: 10.1038/s41398-018-0298-0

Author

Cherepkova, Elena V. ; Maksimov, Vladimir V. ; Aftanas, Lyubomir I. / Polymorphism of serotonin transporter gene in male subjects with antisocial behavior and MMA fighters. в: Translational Psychiatry. 2018 ; Том 8, № 1. стр. 248.

BibTeX

@article{0d4017a285864eaea6b55c29e467c175,
title = "Polymorphism of serotonin transporter gene in male subjects with antisocial behavior and MMA fighters",
abstract = "In our study, the frequencies of serotonin transporter gene (5-HTT) polymorphisms and their combinations are compared in the healthy male subjects with antisocial behavior, in general, and in those with its particular forms, as well as in the reference group of MMA fighters. Subjects convicted of unlawful actions were classified into those convicted of violent crimes or non-violent ones. The group of subjects convicted of violent crimes was further subdivided into those convicted of murder, or robbery, or of inflicting grave body injuries. The group of MMA fighters was selected from the subjects without a prior history of antisocial behavior or criminal record in the subjects or their relatives. The frequency of D allele in the groups of convicted subjects and MMA fighters was higher, than in the population sample. Furthermore, the frequencies of D/D and 12/12 genotype combinations were shown to be higher in the group of convicted subjects, especially, in habitual criminals and those convicted of grave crimes or murder. The predisposition of MMA fighters to violent behavior and physical aggressive suppression of an opponent is successfully implemented in their professional career; however, this behavioral pattern appears to represent the controlled aggression.",
keywords = "Adolescent, Adult, Aggression/physiology, Athletes, Criminals, Humans, Male, Martial Arts/physiology, Middle Aged, Polymorphism, Genetic, Serotonin Plasma Membrane Transport Proteins/genetics, Violence, Young Adult, PERSONALITY-DISORDER, GENOTYPE, PROMOTER POLYMORPHISM, HUMAN-AGGRESSION, CHILDREN, ASSOCIATION",
author = "Cherepkova, {Elena V.} and Maksimov, {Vladimir V.} and Aftanas, {Lyubomir I.}",
year = "2018",
month = dec,
day = "1",
doi = "10.1038/s41398-018-0298-0",
language = "English",
volume = "8",
pages = "248",
journal = "Translational Psychiatry",
issn = "2158-3188",
publisher = "Nature Publishing Group",
number = "1",

}

RIS

TY - JOUR

T1 - Polymorphism of serotonin transporter gene in male subjects with antisocial behavior and MMA fighters

AU - Cherepkova, Elena V.

AU - Maksimov, Vladimir V.

AU - Aftanas, Lyubomir I.

PY - 2018/12/1

Y1 - 2018/12/1

N2 - In our study, the frequencies of serotonin transporter gene (5-HTT) polymorphisms and their combinations are compared in the healthy male subjects with antisocial behavior, in general, and in those with its particular forms, as well as in the reference group of MMA fighters. Subjects convicted of unlawful actions were classified into those convicted of violent crimes or non-violent ones. The group of subjects convicted of violent crimes was further subdivided into those convicted of murder, or robbery, or of inflicting grave body injuries. The group of MMA fighters was selected from the subjects without a prior history of antisocial behavior or criminal record in the subjects or their relatives. The frequency of D allele in the groups of convicted subjects and MMA fighters was higher, than in the population sample. Furthermore, the frequencies of D/D and 12/12 genotype combinations were shown to be higher in the group of convicted subjects, especially, in habitual criminals and those convicted of grave crimes or murder. The predisposition of MMA fighters to violent behavior and physical aggressive suppression of an opponent is successfully implemented in their professional career; however, this behavioral pattern appears to represent the controlled aggression.

AB - In our study, the frequencies of serotonin transporter gene (5-HTT) polymorphisms and their combinations are compared in the healthy male subjects with antisocial behavior, in general, and in those with its particular forms, as well as in the reference group of MMA fighters. Subjects convicted of unlawful actions were classified into those convicted of violent crimes or non-violent ones. The group of subjects convicted of violent crimes was further subdivided into those convicted of murder, or robbery, or of inflicting grave body injuries. The group of MMA fighters was selected from the subjects without a prior history of antisocial behavior or criminal record in the subjects or their relatives. The frequency of D allele in the groups of convicted subjects and MMA fighters was higher, than in the population sample. Furthermore, the frequencies of D/D and 12/12 genotype combinations were shown to be higher in the group of convicted subjects, especially, in habitual criminals and those convicted of grave crimes or murder. The predisposition of MMA fighters to violent behavior and physical aggressive suppression of an opponent is successfully implemented in their professional career; however, this behavioral pattern appears to represent the controlled aggression.

KW - Adolescent

KW - Adult

KW - Aggression/physiology

KW - Athletes

KW - Criminals

KW - Humans

KW - Male

KW - Martial Arts/physiology

KW - Middle Aged

KW - Polymorphism, Genetic

KW - Serotonin Plasma Membrane Transport Proteins/genetics

KW - Violence

KW - Young Adult

KW - PERSONALITY-DISORDER

KW - GENOTYPE

KW - PROMOTER POLYMORPHISM

KW - HUMAN-AGGRESSION

KW - CHILDREN

KW - ASSOCIATION

UR - http://www.scopus.com/inward/record.url?scp=85056627879&partnerID=8YFLogxK

U2 - 10.1038/s41398-018-0298-0

DO - 10.1038/s41398-018-0298-0

M3 - Article

C2 - 30442883

AN - SCOPUS:85056627879

VL - 8

SP - 248

JO - Translational Psychiatry

JF - Translational Psychiatry

SN - 2158-3188

IS - 1

M1 - 248

ER -

ID: 17471797