TY - GEN

T1 - Plant Extracts Provide Antiosteoporotic Effect in Vitro

AU - Slazhneva, Natalya A.

AU - Bahareva, Alina

AU - Bondarenko, Natalya A.

N1 - The study was carried out within the framework of the state assignment of NIIKEL - a branch of the FSBI Federal Research Center Institute of Cytology and Genetics SB RAS on topic No. FWNR-2024-0005.

PY - 2024/11/26

Y1 - 2024/11/26

N2 - Osteoporosis - is a metabolic chronic disease, that affect bone structure, mineralization and density. It creates a high economic and social burden on society, as it leads to frequent fractures and disability of patients. Among the existing methods and drugs for treatment, none of them provides a complete cure for osteoporosis, but only maintains the bone tissue of the body from further destruction. The plant extracts are considered as biological supplements that prevent the development of osteoporosis at early stages, when the use of more serious drugs can only harm the body. The developed plant extracts increase the production of bone collagen and enhance its mineralization with calcium salts, as well as reduce the number of lytic enzymes that contribute to bone destruction. Thus, having a dual effect against osteoporosis, plant extracts may prove to be a promising drug for further in vivo research.

AB - Osteoporosis - is a metabolic chronic disease, that affect bone structure, mineralization and density. It creates a high economic and social burden on society, as it leads to frequent fractures and disability of patients. Among the existing methods and drugs for treatment, none of them provides a complete cure for osteoporosis, but only maintains the bone tissue of the body from further destruction. The plant extracts are considered as biological supplements that prevent the development of osteoporosis at early stages, when the use of more serious drugs can only harm the body. The developed plant extracts increase the production of bone collagen and enhance its mineralization with calcium salts, as well as reduce the number of lytic enzymes that contribute to bone destruction. Thus, having a dual effect against osteoporosis, plant extracts may prove to be a promising drug for further in vivo research.

KW - osteoblasts

KW - osteoclasts

KW - osteoporosis

KW - plant extracts

KW - rice husk

KW - silicon

UR - https://www.scopus.com/record/display.uri?eid=2-s2.0-85212059113&origin=inward&txGid=80a3b19ac6bbc5edabadd14abb82609c

UR - https://www.mendeley.com/catalogue/0ef3913e-5de0-3010-9b54-fbe159850215/

U2 - 10.1109/SIBIRCON63777.2024.10758539

DO - 10.1109/SIBIRCON63777.2024.10758539

M3 - Conference contribution

SN - 9798331532024

T3 - 2024 IEEE International Multi-Conference on Engineering, Computer and Information Sciences, SIBIRCON 2024

SP - 135

EP - 138

BT - 2024 IEEE International Multi-Conference on Engineering, Computer and Information Sciences, SIBIRCON 2024

PB - Institute of Electrical and Electronics Engineers Inc.

T2 - 2024 IEEE International Multi-Conference on Engineering, Computer and Information Sciences

Y2 - 30 September 2024 through 2 November 2024

ER -