Standard

Physicochemical Properties and Anti-Opisthorchosis Effect of Mechanochemically Synthesized Solid Compositions of Praziquantel with Glycyrrhizic Acid Disodium Salt. / Meteleva, E. S.; Chistyachenko, Yu S.; Suntsova, L. P. и др.

в: Doklady Biochemistry and Biophysics, Том 481, № 1, 01.07.2018, стр. 228-231.

Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование

Harvard

Meteleva, ES, Chistyachenko, YS, Suntsova, LP, Tsyganov, MA, Vishnivetskaya, GB, Avgustinovich, DF, Khvostov, MV, Polyakov, NE, Tolstikova, TG, Mordvinov, VA, Dushkin, AV & Lyakhov, NZ 2018, 'Physicochemical Properties and Anti-Opisthorchosis Effect of Mechanochemically Synthesized Solid Compositions of Praziquantel with Glycyrrhizic Acid Disodium Salt', Doklady Biochemistry and Biophysics, Том. 481, № 1, стр. 228-231. https://doi.org/10.1134/S1607672918040142

APA

Meteleva, E. S., Chistyachenko, Y. S., Suntsova, L. P., Tsyganov, M. A., Vishnivetskaya, G. B., Avgustinovich, D. F., Khvostov, M. V., Polyakov, N. E., Tolstikova, T. G., Mordvinov, V. A., Dushkin, A. V., & Lyakhov, N. Z. (2018). Physicochemical Properties and Anti-Opisthorchosis Effect of Mechanochemically Synthesized Solid Compositions of Praziquantel with Glycyrrhizic Acid Disodium Salt. Doklady Biochemistry and Biophysics, 481(1), 228-231. https://doi.org/10.1134/S1607672918040142

Vancouver

Meteleva ES, Chistyachenko YS, Suntsova LP, Tsyganov MA, Vishnivetskaya GB, Avgustinovich DF и др. Physicochemical Properties and Anti-Opisthorchosis Effect of Mechanochemically Synthesized Solid Compositions of Praziquantel with Glycyrrhizic Acid Disodium Salt. Doklady Biochemistry and Biophysics. 2018 июль 1;481(1):228-231. doi: 10.1134/S1607672918040142

Author

Meteleva, E. S. ; Chistyachenko, Yu S. ; Suntsova, L. P. и др. / Physicochemical Properties and Anti-Opisthorchosis Effect of Mechanochemically Synthesized Solid Compositions of Praziquantel with Glycyrrhizic Acid Disodium Salt. в: Doklady Biochemistry and Biophysics. 2018 ; Том 481, № 1. стр. 228-231.

BibTeX

@article{1445b829ae9a4e3f8818dd2c7fe034ac,
title = "Physicochemical Properties and Anti-Opisthorchosis Effect of Mechanochemically Synthesized Solid Compositions of Praziquantel with Glycyrrhizic Acid Disodium Salt",
abstract = "The mechanochemical preparation of solid compositions of praziquantel with plant saponin (glycyrrhizic acid disodium salt) is described. The study of a number of physicochemical parameters showed that dissolving solid compositions in water is accompanied by the inclusion of praziquantel molecules into micelles, which are formed in the solution of the glycyrrhizic acid disodium salt. Using the opisthorchiasis model caused by Opisthorchis felineus, we found a 4- to 11-fold increase in the anthelmintic activity of praziquantel in the composition as compared to the official praziquantel. According to the pharmacokinetic data, the use of the composition increased the bioavailability of praziquantel 3 times.",
author = "Meteleva, {E. S.} and Chistyachenko, {Yu S.} and Suntsova, {L. P.} and Tsyganov, {M. A.} and Vishnivetskaya, {G. B.} and Avgustinovich, {D. F.} and Khvostov, {M. V.} and Polyakov, {N. E.} and Tolstikova, {T. G.} and Mordvinov, {V. A.} and Dushkin, {A. V.} and Lyakhov, {N. Z.}",
note = "Publisher Copyright: {\textcopyright} 2018, Pleiades Publishing, Ltd.",
year = "2018",
month = jul,
day = "1",
doi = "10.1134/S1607672918040142",
language = "English",
volume = "481",
pages = "228--231",
journal = "Doklady Biochemistry and Biophysics",
issn = "1607-6729",
publisher = "Maik Nauka-Interperiodica Publishing",
number = "1",

}

RIS

TY - JOUR

T1 - Physicochemical Properties and Anti-Opisthorchosis Effect of Mechanochemically Synthesized Solid Compositions of Praziquantel with Glycyrrhizic Acid Disodium Salt

AU - Meteleva, E. S.

AU - Chistyachenko, Yu S.

AU - Suntsova, L. P.

AU - Tsyganov, M. A.

AU - Vishnivetskaya, G. B.

AU - Avgustinovich, D. F.

AU - Khvostov, M. V.

AU - Polyakov, N. E.

AU - Tolstikova, T. G.

AU - Mordvinov, V. A.

AU - Dushkin, A. V.

AU - Lyakhov, N. Z.

N1 - Publisher Copyright: © 2018, Pleiades Publishing, Ltd.

PY - 2018/7/1

Y1 - 2018/7/1

N2 - The mechanochemical preparation of solid compositions of praziquantel with plant saponin (glycyrrhizic acid disodium salt) is described. The study of a number of physicochemical parameters showed that dissolving solid compositions in water is accompanied by the inclusion of praziquantel molecules into micelles, which are formed in the solution of the glycyrrhizic acid disodium salt. Using the opisthorchiasis model caused by Opisthorchis felineus, we found a 4- to 11-fold increase in the anthelmintic activity of praziquantel in the composition as compared to the official praziquantel. According to the pharmacokinetic data, the use of the composition increased the bioavailability of praziquantel 3 times.

AB - The mechanochemical preparation of solid compositions of praziquantel with plant saponin (glycyrrhizic acid disodium salt) is described. The study of a number of physicochemical parameters showed that dissolving solid compositions in water is accompanied by the inclusion of praziquantel molecules into micelles, which are formed in the solution of the glycyrrhizic acid disodium salt. Using the opisthorchiasis model caused by Opisthorchis felineus, we found a 4- to 11-fold increase in the anthelmintic activity of praziquantel in the composition as compared to the official praziquantel. According to the pharmacokinetic data, the use of the composition increased the bioavailability of praziquantel 3 times.

UR - http://www.scopus.com/inward/record.url?scp=85052732665&partnerID=8YFLogxK

U2 - 10.1134/S1607672918040142

DO - 10.1134/S1607672918040142

M3 - Article

C2 - 30168067

AN - SCOPUS:85052732665

VL - 481

SP - 228

EP - 231

JO - Doklady Biochemistry and Biophysics

JF - Doklady Biochemistry and Biophysics

SN - 1607-6729

IS - 1

ER -

ID: 16330037