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Photocontrolled release of nitric oxide for precise management of NO concentration in a solution. / Жермоленко, Егор Олегович; Карогодина, Татьяна Юрьевна; Воробьев, Алексей Юрьевич и др.

в: Materials Today Chemistry, Том 29, 101445, 04.2023.

Результаты исследований: Научные публикации в периодических изданияхстатьяРецензирование

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Жермоленко ЕО, Карогодина ТЮ, Воробьев АЮ, Панфилов МА, Москаленский АЕ. Photocontrolled release of nitric oxide for precise management of NO concentration in a solution. Materials Today Chemistry. 2023 апр.;29:101445. doi: 10.1016/j.mtchem.2023.101445

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BibTeX

@article{a948853f09ec4f91aa713f367338380a,
title = "Photocontrolled release of nitric oxide for precise management of NO concentration in a solution",
abstract = "Nitric oxide (NO) is a unique biochemical mediator involved in the regulation of vital processes. Its short half-life and local action impede direct application in medical practice. Light-controllable NO releasers are promising for the development of smart therapies. Here, we present novel aza-BODIPY derivative containing N-nitroso moiety, which shows efficient and reversible release of NO under red light. Using this molecule, we demonstrate a system for precise management of NO concentration in aqueous solution in vitro using the feedback loop with optical control. Our results could serve as the basis for the development of novel therapeutic methods.",
keywords = "nitric oxide, NO donors, aza-BODIPY",
author = "Жермоленко, {Егор Олегович} and Карогодина, {Татьяна Юрьевна} and Воробьев, {Алексей Юрьевич} and Панфилов, {Михаил Андреевич} and Москаленский, {Александр Ефимович}",
note = "The study was supported by the Russian Science Foundation (grant # 18-15-00049).",
year = "2023",
month = apr,
doi = "10.1016/j.mtchem.2023.101445",
language = "English",
volume = "29",
journal = "Materials Today Chemistry",
issn = "2468-5194",
publisher = "Elsevier Ltd",

}

RIS

TY - JOUR

T1 - Photocontrolled release of nitric oxide for precise management of NO concentration in a solution

AU - Жермоленко, Егор Олегович

AU - Карогодина, Татьяна Юрьевна

AU - Воробьев, Алексей Юрьевич

AU - Панфилов, Михаил Андреевич

AU - Москаленский, Александр Ефимович

N1 - The study was supported by the Russian Science Foundation (grant # 18-15-00049).

PY - 2023/4

Y1 - 2023/4

N2 - Nitric oxide (NO) is a unique biochemical mediator involved in the regulation of vital processes. Its short half-life and local action impede direct application in medical practice. Light-controllable NO releasers are promising for the development of smart therapies. Here, we present novel aza-BODIPY derivative containing N-nitroso moiety, which shows efficient and reversible release of NO under red light. Using this molecule, we demonstrate a system for precise management of NO concentration in aqueous solution in vitro using the feedback loop with optical control. Our results could serve as the basis for the development of novel therapeutic methods.

AB - Nitric oxide (NO) is a unique biochemical mediator involved in the regulation of vital processes. Its short half-life and local action impede direct application in medical practice. Light-controllable NO releasers are promising for the development of smart therapies. Here, we present novel aza-BODIPY derivative containing N-nitroso moiety, which shows efficient and reversible release of NO under red light. Using this molecule, we demonstrate a system for precise management of NO concentration in aqueous solution in vitro using the feedback loop with optical control. Our results could serve as the basis for the development of novel therapeutic methods.

KW - nitric oxide, NO donors, aza-BODIPY

UR - https://www.scopus.com/record/display.uri?eid=2-s2.0-85149828946&origin=inward&txGid=aac2186ee6409d8e75f01c9b160a884a

U2 - 10.1016/j.mtchem.2023.101445

DO - 10.1016/j.mtchem.2023.101445

M3 - Article

VL - 29

JO - Materials Today Chemistry

JF - Materials Today Chemistry

SN - 2468-5194

M1 - 101445

ER -

ID: 55420770