Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Personalized Approach to Determination of Histidine-Rich Glycoprotein and E-Cadherin in Supernatants of Immunocompetent Blood Cells and Breast Biopsy Specimens in Breast Malignant and Non-Malignant Disease. / Autenshlyus, A. I.; Bernado, A. V.; Studenikina, A. A. и др.
в: Doklady Biochemistry and Biophysics, Том 490, № 1, 01.01.2020, стр. 1-4.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
}
TY - JOUR
T1 - Personalized Approach to Determination of Histidine-Rich Glycoprotein and E-Cadherin in Supernatants of Immunocompetent Blood Cells and Breast Biopsy Specimens in Breast Malignant and Non-Malignant Disease
AU - Autenshlyus, A. I.
AU - Bernado, A. V.
AU - Studenikina, A. A.
AU - Proskura, A. V.
AU - Davletova, K. I.
AU - Zhurakovskiy, I. P.
AU - Arkhipov, S. A.
AU - Varaksin, N. A.
AU - Sidorov, S. V.
AU - Lyakhovich, V. V.
PY - 2020/1/1
Y1 - 2020/1/1
N2 - The material of patients with invasive carcinoma of no special type (ICNT) and nonmalignant diseases (ND) of the mammary gland was studied. When comparing the concentrations of histidine-rich glycoprotein (HRG) and E-cadherin (CDH1), statistically significant differences between ICNT and ND by HRG in the supernatant of blood cells and its spontaneous production by biopsies and by CDH1 at its induced production, as well as by influence indices of polyclonal activators on the production of CDH1 were found. When comparing the expression of immunohistochemical markers, no statistically significant differences between ICNT and ND were obtained.
AB - The material of patients with invasive carcinoma of no special type (ICNT) and nonmalignant diseases (ND) of the mammary gland was studied. When comparing the concentrations of histidine-rich glycoprotein (HRG) and E-cadherin (CDH1), statistically significant differences between ICNT and ND by HRG in the supernatant of blood cells and its spontaneous production by biopsies and by CDH1 at its induced production, as well as by influence indices of polyclonal activators on the production of CDH1 were found. When comparing the expression of immunohistochemical markers, no statistically significant differences between ICNT and ND were obtained.
KW - breast diseases
KW - cadherin-E
KW - histidine-rich glycoprotein
KW - immunohistochemical markers
KW - proteomics
UR - http://www.scopus.com/inward/record.url?scp=85083954890&partnerID=8YFLogxK
U2 - 10.1134/S1607672920010019
DO - 10.1134/S1607672920010019
M3 - Article
C2 - 32342301
AN - SCOPUS:85083954890
VL - 490
SP - 1
EP - 4
JO - Doklady Biochemistry and Biophysics
JF - Doklady Biochemistry and Biophysics
SN - 1607-6729
IS - 1
ER -
ID: 24230740