Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Paramagnetic Re(I) complexes with azolyl-nitroxide ligands. / Chernavin, Platon; Maryunina, Kseniya; Letyagin, Gleb и др.
в: Polyhedron, Том 243, 116524, 01.10.2023.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Paramagnetic Re(I) complexes with azolyl-nitroxide ligands
AU - Chernavin, Platon
AU - Maryunina, Kseniya
AU - Letyagin, Gleb
AU - Romanenko, Galina
AU - Tumanov, Sergey
AU - Veber, Sergey
AU - Fedin, Matvey
AU - Bogomyakov, Artem
AU - Ovcharenko, Victor
N1 - Acknowledgments: The research was carried out within the state assignment of Ministry of Science and Higher Education of the Russian Federation (theme No.121012290037-2), EPR spectroscopy characterization of studied samples was funded by the Russian Science Foundation (grant number 22-13-00376).
PY - 2023/10/1
Y1 - 2023/10/1
N2 - A one-stage synthesis of paramagnetic Re(I) compounds based on the reaction of [Re(CO)5Br] with spin-labeled N-donor heterocycles was developed. Nitronyl nitroxide derivatives of 1H-imidazole (L1), 1H-pyrazole (L2), di(1H-pyrazol-1-yl)methane (L3) and 4-methyl-2-(1H-pyrazol-1-yl)quinoline (L4) can easily substitute two coordinated CO molecules in [Re(CO)5Br], resulting in a series of paramagnetic fac-[Re(CO)3(Li)nBr]·xSolv complexes. Single crystal XRD studies showed that the paramagnetic L1-L4 ligands are coordinated by Re(I) through the imine atoms N of the heterocycles. According to SQUID measurements and EPR spectroscopy data, magnetic behavior of [Re(CO)3(L1)2Br] (1), [Re(CO)3(L2)2Br] (2), and [Re(CO)3(L3)Br] (3) complexes are typical for biradicals, while [Re(CO)3(L4)Br] (4) is typical for monoradical. The combination of Re(I) therapeutic properties and contrasting characteristics of nitroxide radicals in diagnostic magnetic resonance imaging, stability and simplicity of synthesis make [Re(CO)3(Li)nBr] valuable model objects for material design for theranostics purposes.
AB - A one-stage synthesis of paramagnetic Re(I) compounds based on the reaction of [Re(CO)5Br] with spin-labeled N-donor heterocycles was developed. Nitronyl nitroxide derivatives of 1H-imidazole (L1), 1H-pyrazole (L2), di(1H-pyrazol-1-yl)methane (L3) and 4-methyl-2-(1H-pyrazol-1-yl)quinoline (L4) can easily substitute two coordinated CO molecules in [Re(CO)5Br], resulting in a series of paramagnetic fac-[Re(CO)3(Li)nBr]·xSolv complexes. Single crystal XRD studies showed that the paramagnetic L1-L4 ligands are coordinated by Re(I) through the imine atoms N of the heterocycles. According to SQUID measurements and EPR spectroscopy data, magnetic behavior of [Re(CO)3(L1)2Br] (1), [Re(CO)3(L2)2Br] (2), and [Re(CO)3(L3)Br] (3) complexes are typical for biradicals, while [Re(CO)3(L4)Br] (4) is typical for monoradical. The combination of Re(I) therapeutic properties and contrasting characteristics of nitroxide radicals in diagnostic magnetic resonance imaging, stability and simplicity of synthesis make [Re(CO)3(Li)nBr] valuable model objects for material design for theranostics purposes.
UR - https://www.scopus.com/record/display.uri?eid=2-s2.0-85164340054&origin=inward&txGid=b1082f49f8aaffa32e9f6ad7beb9312d
UR - https://www.mendeley.com/catalogue/1ed7ab76-82ba-32eb-b41f-8883d518ec4d/
U2 - 10.1016/j.poly.2023.116524
DO - 10.1016/j.poly.2023.116524
M3 - Article
VL - 243
JO - Polyhedron
JF - Polyhedron
SN - 0277-5387
M1 - 116524
ER -
ID: 53971911