TY - JOUR

T1 - Octahedral molybdenum cluster as a photoactive antimicrobial additive to a fluoroplastic

AU - Vorotnikova, Natalia A.

AU - Alekseev, Alexander Y.

AU - Vorotnikov, Yuri A.

AU - Evtushok, Darya V.

AU - Molard, Yann

AU - Amela-Cortes, Maria

AU - Cordier, Stéphane

AU - Smolentsev, Anton I.

AU - Burton, Christian G.

AU - Kozhin, Peter M.

AU - Zhu, Patricia

AU - Topham, Paul D.

AU - Mironov, Yuri V.

AU - Bradley, Mark

AU - Efremova, Olga A.

AU - Shestopalov, Michael A.

N1 - Publisher Copyright: © 2019 Elsevier B.V.

PY - 2019/12/1

Y1 - 2019/12/1

N2 - Finding methods that fight bacterial infection or contamination, while minimising our reliance on antibiotics is one of the most pressing needs of this century. Although the utilisation of UV-C light and strong oxidising agents, such as bleach, are still efficacious methods for eliminating bacterial surface contamination, both methods present severe health and/or environmental hazards. Materials with intrinsic photodynamic activity (i.e. a material's ability upon photoexcitation to convert molecular oxygen into reactive oxygen species such as singlet oxygen), which work with light within the visible photomagnetic spectrum could offer a significantly safer alternative. Here we present a new, bespoke molybdenum cluster (Bu4N)2[{Mo6I8}(CF3(CF2)6COO)6], which is both efficient in the generation of singlet oxygen upon photoirradiation and compatible with the fluoropolymer (F-32L) known for its good oxygen permeability. Thus, (Bu4N)2[{Mo6I8 }(CF3(CF2)6COO)6]/F-32L mixtures have been solution-processed to give homogenous films of smooth and fibrous morphologies and which displayed high photoinduced antibacterial activity against four common pathogens under visible light irradiation. These materials thus have potential in applications ranging from antibacterial coatings to filtration membranes and air conditioners to prevent spread of bacterial infections.

AB - Finding methods that fight bacterial infection or contamination, while minimising our reliance on antibiotics is one of the most pressing needs of this century. Although the utilisation of UV-C light and strong oxidising agents, such as bleach, are still efficacious methods for eliminating bacterial surface contamination, both methods present severe health and/or environmental hazards. Materials with intrinsic photodynamic activity (i.e. a material's ability upon photoexcitation to convert molecular oxygen into reactive oxygen species such as singlet oxygen), which work with light within the visible photomagnetic spectrum could offer a significantly safer alternative. Here we present a new, bespoke molybdenum cluster (Bu4N)2[{Mo6I8}(CF3(CF2)6COO)6], which is both efficient in the generation of singlet oxygen upon photoirradiation and compatible with the fluoropolymer (F-32L) known for its good oxygen permeability. Thus, (Bu4N)2[{Mo6I8 }(CF3(CF2)6COO)6]/F-32L mixtures have been solution-processed to give homogenous films of smooth and fibrous morphologies and which displayed high photoinduced antibacterial activity against four common pathogens under visible light irradiation. These materials thus have potential in applications ranging from antibacterial coatings to filtration membranes and air conditioners to prevent spread of bacterial infections.

KW - Anti-bacterial materials

KW - Octahedral molybdenum cluster

KW - Photo-dynamic inactivation

KW - BR

KW - SERIES

KW - SINGLET OXYGEN LIFETIME

KW - COMPLEXES

KW - RESISTANCE

KW - REDOX

KW - CL

KW - PHOTODYNAMIC INACTIVATION

UR - http://www.scopus.com/inward/record.url?scp=85071680955&partnerID=8YFLogxK

U2 - 10.1016/j.msec.2019.110150

DO - 10.1016/j.msec.2019.110150

M3 - Article

C2 - 31546442

AN - SCOPUS:85071680955

VL - 105

JO - Materials Science and Engineering C

JF - Materials Science and Engineering C

SN - 0928-4931

M1 - 110150

ER -