Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
Neutron source based on vacuum insulated tandem accelerator and lithium target. / Taskaev, Sergey; Berendeev, Evgenii; Bikchurina, Marina и др.
в: Biology, Том 10, № 5, 350, 05.2021.Результаты исследований: Научные публикации в периодических изданиях › статья › Рецензирование
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TY - JOUR
T1 - Neutron source based on vacuum insulated tandem accelerator and lithium target
AU - Taskaev, Sergey
AU - Berendeev, Evgenii
AU - Bikchurina, Marina
AU - Bykov, Timofey
AU - Kasatov, Dmitrii
AU - Kolesnikov, Iaroslav
AU - Koshkarev, Alexey
AU - Makarov, Aleksandr
AU - Ostreinov, Georgii
AU - Porosev, Vyacheslav
AU - Savinov, Sergey
AU - Shchudlo, Ivan
AU - Sokolova, Evgeniia
AU - Sorokin, Igor
AU - Sycheva, Tatiana
AU - Verkhovod, Gleb
N1 - Funding Information: Funding: This research was funded by Russian Science Foundation, grant number 19-72-30005. Publisher Copyright: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. Copyright: Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2021/5
Y1 - 2021/5
N2 - A compact accelerator-based neutron source has been proposed and created at the Budker Institute of Nuclear Physics in Novosibirsk, Russia. An original design tandem accelerator is used to provide a proton beam. The proton beam energy can be varied within a range of 0.6–2.3 MeV, keeping a high-energy stability of 0.1%. The beam current can also be varied in a wide range (from 0.3 mA to 10 mA) with high current stability (0.4%). In the device, neutron flux is generated as a result of the7Li(p,n)7Be threshold reaction. A beam-shaping assembly is applied to convert this flux into a beam of epithermal neutrons with characteristics suitable for BNCT. A lot of scientific research has been carried out at the facility, including the study of blistering and its effect on the neutron yield. The BNCT technique is being tested in in vitro and in vivo studies, and the methods of dosimetry are being developed. It is planned to certify the neutron source next year and conduct clinical trials on it. The neutron source served as a prototype for a facility created for a clinic in Xiamen (China).
AB - A compact accelerator-based neutron source has been proposed and created at the Budker Institute of Nuclear Physics in Novosibirsk, Russia. An original design tandem accelerator is used to provide a proton beam. The proton beam energy can be varied within a range of 0.6–2.3 MeV, keeping a high-energy stability of 0.1%. The beam current can also be varied in a wide range (from 0.3 mA to 10 mA) with high current stability (0.4%). In the device, neutron flux is generated as a result of the7Li(p,n)7Be threshold reaction. A beam-shaping assembly is applied to convert this flux into a beam of epithermal neutrons with characteristics suitable for BNCT. A lot of scientific research has been carried out at the facility, including the study of blistering and its effect on the neutron yield. The BNCT technique is being tested in in vitro and in vivo studies, and the methods of dosimetry are being developed. It is planned to certify the neutron source next year and conduct clinical trials on it. The neutron source served as a prototype for a facility created for a clinic in Xiamen (China).
KW - Boron neutron capture therapy
KW - Charge particle accelerator
KW - Lithium target
KW - Neutron detector
KW - Neutron source
UR - http://www.scopus.com/inward/record.url?scp=85105172446&partnerID=8YFLogxK
U2 - 10.3390/biology10050350
DO - 10.3390/biology10050350
M3 - Article
C2 - 33919153
AN - SCOPUS:85105172446
VL - 10
JO - Biology
JF - Biology
SN - 2079-7737
IS - 5
M1 - 350
ER -
ID: 28511594