TY - JOUR

T1 - Neuroimaging in Moyamoya angiopathy: Updated review

AU - Filimonova, E.

AU - Ovsiannikov, K.

AU - Rzaev, J.

N1 - Funding Information: We thank Alexey Gogolev (Federal Center of Neurosurgery Novosibirsk) for providing Fig. 1. Publisher Copyright: © 2022 Elsevier B.V.

PY - 2022/11

Y1 - 2022/11

N2 - Moyamoya angiopathy (MMA) is a rare condition characterized by steno-occlusion of terminal portions of the internal carotid arteries and/or their proximal branches with the formation of collateral vessels network (moyamoya vessels). These changes result in chronic ischemia of the brain parenchyma with subsequent serious cerebrovascular accidents. The prognosis of MMA could be dramatically improved if the diagnosis and assessment are prompt and accurate. It is also crucial to define the indications, optimal timing, volume, and tactics of revascularization surgery, as well as longitudinal observation after treatment. It is therefore necessary to use strict criteria for decision making, including radiological criteria. In today's world, neuroimaging is a valuable diagnostic tool that continually evolves and provides us with more and more information about structural and functional changes in different pathological conditions. However, due to MMA's rarity, its neuroimaging can be challenging. The purpose of this review is to summarize a contemporary knowledge regarding neuroimaging in patients with MMA and to discuss the main difficulties associated with visualizing this condition.

AB - Moyamoya angiopathy (MMA) is a rare condition characterized by steno-occlusion of terminal portions of the internal carotid arteries and/or their proximal branches with the formation of collateral vessels network (moyamoya vessels). These changes result in chronic ischemia of the brain parenchyma with subsequent serious cerebrovascular accidents. The prognosis of MMA could be dramatically improved if the diagnosis and assessment are prompt and accurate. It is also crucial to define the indications, optimal timing, volume, and tactics of revascularization surgery, as well as longitudinal observation after treatment. It is therefore necessary to use strict criteria for decision making, including radiological criteria. In today's world, neuroimaging is a valuable diagnostic tool that continually evolves and provides us with more and more information about structural and functional changes in different pathological conditions. However, due to MMA's rarity, its neuroimaging can be challenging. The purpose of this review is to summarize a contemporary knowledge regarding neuroimaging in patients with MMA and to discuss the main difficulties associated with visualizing this condition.

KW - Brain perfusion

KW - Computer tomography angiography (CTA)

KW - Digital subtraction angiography (DSA)

KW - Magnetic resonance angiography (MRA)

KW - Magnetic resonance imaging (MRI)

KW - Moyamoya angiopathy (MMA)

KW - Neuroimaging

KW - Humans

KW - Magnetic Resonance Angiography

KW - Angiography, Digital Subtraction

KW - Cerebral Angiography/methods

KW - Moyamoya Disease/diagnostic imaging

KW - Brain/diagnostic imaging

UR - http://www.scopus.com/inward/record.url?scp=85140079017&partnerID=8YFLogxK

UR - https://www.mendeley.com/catalogue/28d68524-f62c-350e-810b-457bf23a0696/

U2 - 10.1016/j.clineuro.2022.107471

DO - 10.1016/j.clineuro.2022.107471

M3 - Review article

C2 - 36265242

AN - SCOPUS:85140079017

VL - 222

JO - Clinical Neurology and Neurosurgery

JF - Clinical Neurology and Neurosurgery

SN - 0303-8467

M1 - 107471

ER -